Now showing items 41-60 of 71

    • Veloso Matta, Pablo; Fernández, Alejandra; Terraza, Claudia; Álvarez Rivas, Carla; Vernal Astudillo, Rolando; Escobar Álvarez, Alejandro; Hernández Ríos, Emma (Springer, 2020)
      Objectives To explore the macrophage profiles in symptomatic and asymptomatic forms of AP through phenotypic and functional analyses. Material and methods Cross-sectional study. Apical tissue/lesion samples were collected ...
    • Hernández Ríos, Emma; Valenzuela, María Antonieta; López Otin, Carlos; Alvarez, Jesús; López, José Manuel; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2006-11)
      Background: Matrix metalloproteinases (MMPs) participate in extracellular matrix degradation in physiological and pathological conditions. The available evidence suggests that MMP-13 plays a significant role in both the ...
    • Ortiz, María Carolina; Lefimil Puente, Claudia; Rodas, Paula I.; Vernal Astudillo, Rolando; López, Mercedes; Acuña Castillo, Claudio; Imarai, Mónica; Escobar, Alejandro (Public Library Science, 2015)
      Current data suggest that Neisseria gonorrhoeae is able to suppress the protective immune response at different levels, such as B and T lymphocytes and antigen-presenting cells. The present report is focused on gonococcus ...
    • Dutzan Muñoz, Nicolás (Universidad de Chile, 2003)
      La periodontitis es una enfermedad infecciosa de naturaleza inflamatoria, que involucra una respuesta inmune del hospedero y que se caracteriza por la destrucción de los tejidos de inserción del diente. Numerosos estudios ...
    • Monasterio, Gustavo; Ormeño Castillo, Francisca; Astorga, Jéssica; Hoare Teuche, Anilei; Terraza, Claudia; Cafferata, Emilio A.; Villablanca, Eduardo J.; Vernal Astudillo, Rolando Marcelo (Frontiers Media, 2020)
      Aggregatibacter actinomycetemcomitans is a Gram-negative oral bacterium with high immunostimulatory and pathogenic potential involved in the onset and progression of periodontitis, a chronic disease characterized by aberrant ...
    • Dutzan Muñoz, Nicolás; Gamonal Aravena, Jorge Antonio; Silva, Augusto; Sanz, Mariano; Vernal Astudillo, Rolando (John Wiley, 2009)
      Aim: T regulatory (Treg) cells have been detected in periodontitis lesions, and forkhead box P3 (Foxp3) expression has been negatively correlated to receptor activator of nuclear factor-k B ligand (RANKL). The aim of ...
    • Dutzan Muñoz, Nicolás; Gamonal Aravena, Jorge Antonio; Silva, Augusto; Sanz, Mariano; Vernal Astudillo, Rolando (John Wiley & Sons, 2009-05)
      Aim: T regulatory (Treg) cells have been detected in periodontitis lesions, and forkhead box P3 (Foxp3) expression has been negatively correlated to receptor activator of nuclear factor-κ B ligand (RANKL). The aim of this ...
    • Dutzan Muñoz, Nicolás; Gamonal Aravena, Jorge Antonio; Silva, Augusto; Sanz, Mariano; Vernal Astudillo, Rolando (2009)
      Aim: T regulatory (Treg) cells have been detected in periodontitis lesions, and forkhead box P3 (Foxp3) expression has been negatively correlated to receptor activator of nuclear factor-κ B ligand (RANKL). The aim of this ...
    • Cafferata Chea, Emilio; Monasterio Ocares, Gustavo; Castillo Franzoy, Francisca; Carvajal Pavez, Paola; Flores Sepúlveda, Guillermo; Díaz Guzmán, Walter; Fuentes del Campo, Aler; Vernal Astudillo, Rolando (Wiley, 2020)
      Objective This study aimed to determine the expression of distinct matrix metalloproteinases, cytokines, and bone resorptive factors in temporomandibular joint osteoarthritis (TMJ-OA) patients and their association with ...
    • Hernández Ríos, Patricia; Pussinen, Pirkko J.; Vernal Astudillo, Rolando; Hernández, Marcela (Frontiers Media SA, 2017)
      Oxidative stress is involved in the pathogenesis of a variety of inflammatory disorders. Apical periodontitis (AP) usually results in the formation of an osteolytic apical lesion (AL) caused by the immune response to ...
    • Carvajal, Paola; Vernal Astudillo, Rolando; Reinero, Daniela; Malheiros, Zilson; Stewart, Bernal; Pannuti, Claudio Mendes; Romito, Giuseppe Alexandre (Sociedade Brasileira de Pesquisa Odontologica, 2020)
      The epidemiological data on gingivitis and periodontitis in Latin America are scarce, as the majority of the Latin American studies have analyzed probing depth instead of clinical attachment loss. Reported data have shown ...
    • Monasterio Ocares, María Carolina; Castillo, F.; García, K.; Álvarez, C.; Rojas, L.; Núñez, C.; Flores, G.; Díaz Guzmán, Walter; Vernal Astudillo, Rolando (2016)
    • Bersezio Miranda, Cristian; Martín, Javier; Mayer, Carla; Rivera, Oriana; Estay, Juan; Vernal Astudillo, Rolando; Haidar, Ziyad S.; Angel, Pablo; Oliveira, Osmir Batista; Fernández Godoy, Eduardo (Springer International Publishing, 2018)
      © 2018, Springer Nature Switzerland AG. Purpose: Intracoronary bleaching is a minimally invasive, alternative treatment that addresses aesthetic concerns related to non-vital teeth discoloration. However, to the best of ...
    • Vernal Astudillo, Rolando; Dezerega Piwonka, Andrea; Dutzan Muñoz, Nicolás; Chaparro, Alejandra; León Berríos, Rubén; Chandía Espinosa, Sabrita; Silva, A.; Gamonal Aravena, Jorge Antonio (BLACKWELL, 2006-05)
      OBJECTIVES: The cytokine receptor activator of nuclear factor kappa B-ligand (RANKL) has been involved in both the physiological and pathological regulation of osteoclast life span and bone metabolism. Periapical granuloma ...
    • Álvarez, Carla; Suliman, Salwa; Almarhoumi, Rawan; Vega, María Elena; Rojas, Carolina; Monasterio, Gustavo; Galindo, Mario; Vernal Astudillo, Rolando; Kantarci, Alpdogan (Nature, 2020)
      The alveolar bone resorption is a distinctive feature of periodontitis progression and determinant for tooth loss. Regulatory T lymphocytes (Tregs) display immuno-suppressive mechanisms and tissue repairing functions, which ...
    • Alvarez, Carla; Rojas Rojas, Carolina Andrea; Rojas, Leticia; Cafferata, Emilio A.; Monasterio, Gustavo; Vernal Astudillo, Rolando (Hindawi Ltd, 2018)
      Periodontitis is a chronic immuno-inflammatory disease in which the disruption of the balance between host and microbiota interactions is key to the onset and progression of the disease. The immune homeostasis associated ...
    • Vernal Astudillo, Rolando; Velásquez, E.; Gamonal Aravena, Jorge Antonio (2007)
      Propósito. La osteoartritis temporomandibular es una enfermedad articular degenerativa, caracterizada por la destrucción del cartílago y hueso articular consecutiva a la respuesta inflamatoria e inmune desarrollada. En ...
    • Rojas, Leticia; Melgar Rodríguez, Samanta; Díaz Zúñiga, Jaime; Alvarez, Carla; Monasterio, Gustavo; Rojas, Carolina; Carvajal, Paola; Vernal Astudillo, Rolando (Elsevier Ltd, 2018)
      Objective: In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on LPS antigenicity. Mixed infection with the different A. actinomycetemcomitans serotypes is frequent in periodontitis ...
    • Díaz Zúñiga, Jaime; Yáñez Figueroa, Juan Pablo; Álvarez, Carla; Melgar Rodríguez, Samanta; Hernández Ríos, Emma; Sanz, Mariano; Vernal Astudillo, Rolando (2014)
      Aim: Different serotypes of Aggregatibacter actinomycetemcomitans have been described based on the lipopolysaccharide (LPS)-O-polysaccharide antigenicity. In turn, a distinct effect of A. actinomycetemcomitans serotypes ...
    • Restaino Bianchi, Carmen Gloria; Chaparro, Alejandra; Valenzuela, María Antonieta; Kettlun, Ana María; Vernal Astudillo, Rolando; Silva, A.; Puente Piccardo, Javier; Jaque, M. P.; León Berríos, Rubén; Gamonal Aravena, Jorge Antonio (2007)
      OBJECTIVE: Neutrophils play a crucial role in the defense of invading bacteria by releasing biologically active molecules. The response of peripheral blood neutrophils was studied in periodontitis-affected patients and in ...