Browsing by Author "Aguillón Gutiérrez, Juan Carlos"
Now showing items 1-20 of 25
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(Universidad de Chile, 2007)La artritis reumatoide es una enfermedad autoinmune sistémica crónica que se caracteriza por presentar hipertrofia de la membrana sinovial, formando un tejido de granulación llamado pannus, el que invade y destruye hueso ...
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(EDP Sciences, 2003)It is likely that the murine response to human recombinant TNFα (hrTNFα) may generate antibodies (Ab) to epitopes present in TNFα from other species. Here, we demonstrate that F5 anti-hrTNFα monoclonal antibody (mAb) ...
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(1991)Two strains of mice, A. SW (H-2(s)) and A.CA (H-2(f)), were immunized with live trypomastigotes or epimastigotes of the Tulahuen strain of Trypanosoma cruzi or with their sonicates. By immunowestern blotting, sera from ...
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Anticuerpos policlonales antiinmunoglobulinas de salmón; herramientas potenciales para diagnóstico (1997)Immunoglobulins (Igs) from sera of Atlantic salmon (Salmo salar) were purified with 50% saturated ammonium sulphate followed by molecular sieving chromatography using Sephacryl S-300. The fraction of purified Igs was used ...
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(2010)Introduction: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory ...
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(Universidad de ChilePrograma Cybertesis, 2006)Las células dendríticas (DC) son células presentadoras de antígeno (APC) profesionales que juegan un papel principal en la iniciación de la respuesta inmune primaria y secundaria. Se encuentran en distintos estados ...
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(Spandidos Publ. Ltd., 2016)Gastric cancer (GC) is the third most common cause of cancer death worldwide. Natural killer cells play an important role in the immune defense against transformed cells. They express the activating receptor NKG2D, whose ...
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(Universidad de Chile, 2022)La Artritis Reumatoide (AR) es una enfermedad sistémica autoinmune crónica en cuya inmunopatogenia los monocitos cumplen un rol fundamental en el desarrollo y perpetuación de la enfermedad, siendo un potencial blanco de ...
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(Universidad de Chile, 2016)La Esclerosis Sistemica (ES) es una enfermedad autoinmune caracterizada por una fibrosis extensiva en la piel y en órganos internos. Actualmente la fisiopatología de esta enfermedad permanece desconocida, sin embargo ...
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(Universidad de Chile, 2023)La artritis reumatoide (AR) es una enfermedad autoinmune que se genera por la presentación de autoantígenos por parte de las células dendríticas (DCs) a linfocitos T (LT) CD4+, las cuales mediante una cascada de reacciones ...
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(Future Medicine Ltd., 2015)
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(1995)The bovine model is extremely interesting to study several basic aspects of mucosal local immunity. Many reports have shown that, in young calves, the infectivity of enterotoxigenic Escherichia coli may be inhibited by ...
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(Frontiers Media, 2021)Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing immune responses and reestablishing immune ...
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(Public Library Science, 2018)Chinese hamster ovary (CHO) cells are the most frequently used host for commercial production of therapeutic proteins. However, their low protein productivity in culture is the main hurdle to overcome. Mild hypothermia has ...
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(2008)Background: The use of regulatory or immature dendritic cells (DCs) as tools for modulating experimental rheumatoid arthritis is very recent. Tumour necrosis factor (TNF)-stimulated DCs have been shown to restore tolerance ...
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(1991)Immunoaffinity chromatography involves binding of an antigen or antibody to a solid matrix, usually agarose, frequently using the cyanogen bromide method. These methods are laborious, rather expensive, and their use has ...
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(American Society of Tropical Medicine and Hygiene, 1995)In spite of being separated by more than 20 million years of evolution, the murine and human immune systems share extensive similarities. Thus, experimental results obtained with the murine model may have predictive value ...
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(Future Medicine, 2015)Aim: To date, there is no human dendritic cell (DC) based therapy to prevent allograft rejection in transplanted patients. Here, we evaluate a potential protocol using a murine in vivo transplant model. Materials & ...
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(Elsevier GmbH, 2015)© 2014 Elsevier GmbH.Retinoic acid (RA), a vitamin A metabolite, has been attributed to relevant functions in adaptive immunity. On T cells, the disruption on RA signaling alters both CD4+ and CD8+ T cells effector function. ...
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(Universidad de Chile, 2013)La artritis reumatoide (AR) es la enfermedad articular inflamatoria más común que afecta al 1% de la población mundial, de causas multifactoriales, poligénica y autoinmune. Se caracteriza por inflamación articular crónica ...
