Browsing by Author "Araya Maturana, Ramiro"
Now showing items 1-20 of 41
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(Universidad de Chile, 2015)El mitocondrión es un organelo que juega un papel crucial en el metabolismo y la regulación de la muerte celular. Por otra parte, se ha descrito que las células tumorales presentan alteraciones en la bioenergética mitocondrial ...
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(MDPI AG, 2019)© 2019 by the authors.Intramolecular hydrogen bond (IMHB) interactions have attracted considerable attention due to their central role in molecular structure, chemical reactivity, and interactions of biologically active ...
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(Universidad de Chile, 2014)Una serie de alteraciones promueven la transformación de una célula normal a una neoplásica. Entre estas destacan: la resistencia a la muerte celular, una sostenida señalización proliferativa, una evasión al sistema inmune, ...
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(Taylor and Francis Ltd., 2018)Searching for a lubricant to be used in articular bone joints, a new nematic liquid crystal (NLC) was characterised. It is formed by dissolving tetradecyltrimethyl ammonium bromide (TTAB), decanol (DeOH), sodium bromide ...
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(2000)The 1H and 13C NMR spectra of a set of structurally related tricyclic quinones consisting of 4,4-dimethylanthracene-1,9,10(4H)-trione (1), 4,4,6,7-tetramethylanthracene-1,9,10(4H)-trione (2) and the regioisomers 4,4,5-(3), ...
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(1999)The regiosomeric quinones 5-acetyloxymethyl-4,4,8-trimethyl-(5) and 8-acetyloxymethyl-4,4,5-trimethylanthracene-1,9,10(4H)-trione (6) were synthesized and their regiochemistry was assigned on the basis of the unambiguous ...
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(2001)Activation parameters for the rotation around the methylene-nitrogen single bond found in a series of four 2,2'-disubstituted N-acetyl-N-phenylbenzylamines, dissolved in DMSO-d6, were measured employing the temperature ...
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(Bentham Science Publishers B.V., 2016)© 2016 Bentham Science Publishers. Recent evidence highlights that energy requirements of cancer cells vary greatly from normal cells and they exhibit different metabolic phenotypes with variable participation of both ...
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(CSIRO Publishing, 2008)Parathion, an organophosphorous pesticide, presents serious hazards to the environment and health. It inhibits acetylcholinesterase, an enzyme incorporated in the cell membrane. A study on the behaviour of parathion in a ...
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(The Royal Society of Chemistry, 2016)Synovial liquid is a natural lubricant of articular joints, such as shoulders, knees and hips. Thus, the development of biocompatible lubricants that can be employed in medical prosthesis for artificial implants, and ...
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(2006)Three 2′-hydroxy chalcone derivatives were electrochemically reduced to the radical anion by a reversible one-electron transfer followed by a chemical dimerization reaction. Under suitable conditions of the medium, the ...
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(Universidad de Chile, 2015)Estudios previos han demostrado que derivados del ácido gálico unidos a trifenilfosfonio mediante una cadena alifática de diez carbonos son efectivos agentes citotóxicos, desacoplando la cadena transportadora de electrones ...
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(Universidad de ChilePrograma Cybertesis, 2006)Se sintetizó una serie de 3-formilcromonas tricíclicas angulares, por medio de una estrategia sintética de tres etapas consecutivas: ● Reacción Diels-Alder ● Reordenamiento Sigmatrópico [1,5] ● Reacción de Vilsmeier-Haack Se ...
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(MDPI, 2021)Since breast cancer (BC) cells are dependent on mitochondrial bioenergetics for promoting proliferation, survival, and metastasis, mitochondria highlight as an important target for anticancer drug discovery. FRI-1, methyl ...
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(Bentham Science Publishers B.V., 2015)© 2015, Bentham Science Publishers. Curcumin, a natural yellow polyphenol, is isolated from the herb Curcuma longa L. (turmeric), a member of the ginger family. It has been extensively studied due to their multiple ...
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(1996)Aldol reactions lithium alkyl acetates (LiCRR″CO2R′) with (RS)-2-(p-tolylsulfinyl)cyclohexanone (1) (as an epimeric mixture at C-2) take place with very efficient control of the configuration at the tertiary hydroxylic ...
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(Sociedad Chilena de Quimica, 2012)4,4-Dimethyl-5,8-dihydroanthracene-1,9,10(4H)-trione (Q1) and 9,10-Dihydroxy-4,4-dimethyl-5,8-dihydro-1 (4H)-anthracenone (Q2), two molecules that inhibit cancer cell respiration, were selectively deuterated and dissolved ...
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(Sociedade Brasileira de Quimica, 2005)A systematic study about the long-range correlations observed in the HMBC spectra of a series of cis and trans 3-(4-oxo-4H-chromen-3-yl)-acrylic acid ethyl esters, and 5-hydroxy derivatives, was carried out. The results ...
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(2011)A set of regioisomeric pairs of tricyclic hydroquinones, analogues of antitumor 9,10-dihydroxy-4,4-dimethyl-5,8-dihydroanthracen-1(4H)-one (1) and other derivatives, were synthesized and their regiochemistry and NMR spectra ...
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(2014)A study about the oxidative coupling of some representative carbo-and heterocyclic non-symmetrical quinones with aryl-and alkylamines, was carried out comparing dichloromethane and water as reaction mediums. We found that ...
