Browsing by Author "Arredondo Olguín, Miguel"
Now showing items 1-20 of 23
-
Arredondo Olguín, Miguel; Weisstaub Nuta, Sergio; Medina, Marcos; Suazo Romo, Miriam; Guzmán, Miguel; Araya, Magdalena (Elsevier, 2014)It is not clear how frequent is copper deficiency in humans. Current copper markers are not sensitive enough to detect early copper deficiency and new markers are needed. CCS is a candidate to become a copper ...
-
Andrews, Mónica; Soto, Néstor; Arredondo Olguín, Miguel (Elsevier, 2015)Objective: The aim of this study was to determine the association between iron parameters and inflammation in obese individuals with and without type 2 diabetes mellitus (T2DM). Methods: We studied 132 obese individuals ...
-
Flores del Castillo, Sebastián Esteban (Universidad de Chile, 2007)Puede considerarse que el hierro en el organismo se encuentra en dos compartimentos, uno funcional formado por proteínas, entre las que se incluyen la hemoglobina, mioglobina, transferrina y enzimas que requieren hierro ...
-
Mendiburo Seguel, Maria Jose (Universidad de Chile, 2006)
-
Araya, Magdalena; Gutiérrez, Ricardo; Arredondo Olguín, Miguel (Springer, 2014)The chaperone to Zn–Cu superoxide dismutase (CCS) has been postulated as a candidate copper indicator, changing in a consistent manner in induced and recovered copper deficiency, in experimental cell and animal models. ...
-
Hormazábal Muñoz, Daniela Isabel (Universidad de Chile, 2014)Para determinar si la condición de diabetes y/u obesidad está definida por la variación en la expresión de genes relacionados al metabolismo de Fe e inflamación se estudió la abundancia relativa de RNAm de Hepcidina, IL-6, ...
-
Andrews, Mónica; Briones, L.; Jaramillo, A.; Pizarro Aguirre, Fernando; Arredondo Olguín, Miguel (Springer, 2014)Calcium, phytic acid, polyphenols and fiber are major inhibitors of iron absorption and they could be found in excess in some diets, thereby altering or modifying the iron nutrition status. The purpose of this study is ...
-
Jaramillo, Ángela; Briones, Lautaro; Andrews, Mónica; Arredondo Olguín, Miguel; Olivares Grohnert, Manuel; Brito, Alex; Pizarro Aguirre, Fernando (Elsevier, 2015)Objective: To determine the effect of phytic acid, tannic acid and pectin on fasting non-heme iron bioavailability in both the presence and absence of calcium. Research methods: Twenty-eight apparently healthy adult ...
-
Weinborn, Valerie; Pizarro Aguirre, Fernando; Olivares Grohnert, Manuel; Brito, Alex; Arredondo Olguín, Miguel; Flores, Sebastián; Valenzuela Venegas, Carolina (MDPI AG, 2015)The aim of this study is to determine the effect of proteins from cereals and legumes on heme iron (Fe) absorption. The absorption of heme Fe without its native globin was measured. Thirty adult females participated in two ...
-
Pizarro Aguirre, Fernando; Olivares Grohnert, Manuel; Valenzuela Venegas, Carolina; Brito, Alex; Weinborn, Valerie; Flores, Sebastián; Arredondo Olguín, Miguel (Elsevier, 2016)Forty-five women (35-45 year) were randomly assigned to three iron (Fe) absorption sub-studies, which measured the effects of dietary animal proteins on the absorption of heme Fe. Study 1 was focused on heme, red blood ...
-
Espinoza, A.; Morales, S.; Arredondo Olguín, Miguel (Springer, 2014)Epidemiological studies have reported an association between high iron (Fe) levels and elevated risk of developing type 2 diabetes mellitus (T2D). It is believed that the formation of Fe-catalyzed hydroxyl radicals may ...
-
Araya, Magdalena; Kelleher, Shannon; Arredondo Olguín, Miguel; Sierralta, Walter; Vial, María Teresa; Uauy Dagach-Imbarack, Ricardo; Lonnerdal, Bo (AMER SOC CLINICAL NUTRITION, 2005-05)Background: Whether infants regulate copper absorption and the potential effects of excess copper in early life remain poorly defined. Objective: The objective of the study was to assess copper retention, liver copper ...
-
Canales Pangui, Felipe Esteban (Universidad de Chile, 2013)El hierro se encuentra en la dieta en dos formas principalmente, como hierro hemínico (Fe-Hem) y como hierro no hemínico (Fe-no Hem), de los cuales el Fe-hem se acumula en mayor cantidad y por un tiempo prolongado en el ...
-
Betta Morales, Katerina Angélica (Universidad de Chile, 2014)En los Errores Innatos del Metabolismo (EIM), los cultivos de fibroblastos (FB) a partir de biopsia de piel, han sido desarrollados con el objetivo de obtener material para la determinación enzimas deficientes en este ...
-
Briones, L.; Andrews, M.; Pizarro Aguirre, Fernando; Arredondo Olguín, Miguel (Springer Netherlands, 2018)© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Obesity is characterized by a chronic inflammatory process, with an increased volume of total adipose tissue, especially visceral, which secretes ...
-
Andrews Guzmán, Mónica; Arredondo Olguín, Miguel; Olivares Gronhert, Manuel (Grupo Aula Médica, 2015)Objective: To investigate the relationship between oxidative stress and biochemical parameters and the expression of TXNIP, IL-6, IL-1β and TNF-α in peripheral mononuclear cells (PMCs) from type-2 diabetic patients. Methods: ...
-
Arredondo Olguín, Miguel; Martínez, Ronny; Núñez González, Marco; Ruz, Manuel; Olivares, Manuel (SOCIEDAD BIOLGIA CHILE, 2005-05-05)Interactions of micronutrients can affect absorption and bioavailability of other nutrients by a number of mechanisms. In aqueous solutions, and at higher uptake levels, competition between elements with similar chemical ...
-
Arredondo Olguín, Miguel; Mendiburo Seguel, María José; Flores, Sebastián; Singleton, Steven T.; Garrick, Michael D. (Springer Science+Business Media, 2014)Divalent Metal Transporter 1 (DMT1) is an apical Fe transporter in the duodenum and is involved in endosomal Fe export. Four protein isoforms have been described for DMT1, two from mRNA with an iron responsive element ...
-
Jorquera Carvacho, Denisse (Universidad de Chile, 2007)La Hem Oxigenasa 1 (HO-1) es una enzima de expresión inducible que degrada el grupo hem liberando hierro libre (Fe), biliverdina y monóxido de carbono (CO). El Fe es potencialmente tóxico, pues cataliza la formación de ...
-
Le Blanc Soto, Solange Marie Isabelle (Universidad de Chile, 2008)El hierro (Fe) es un elemento vital para la gran mayoría de los organismos debido a que participa en múltiples procesos metabólicos esenciales. Sin embargo, puede llegar a ser tóxico si se encuentra en exceso. En la ...