Browsing by Author "Castro, Pablo"

Now showing items 1-20 of 28

    • Admission hyperglycemia and mortality of st segment elevation myocardial infarction Implicancias de la ... 
      Greig, Douglas; Corbalán, Ramón; Castro, Pablo; Campos, Pabla; Lamich, Rubén; Yovaniniz, Patricio; Nazzal, Carolina (2010)
      Background: Hyperglycemia at admission has been associated to an adverse prognosis in patients with ST-segment elevation acute myocardial infarction (STEMI). However, its impact over the results of reperfusion therapies ...
    • Carvedilol corrects interventricular and interventricular dyssynchrony in chronic heart failure. 
      Castro, Pablo; Mc-Nab, Pablo; Bittner, Alex; Greig, Douglas; Quintana, Juan Carlos; Chiong Lay, Mario; Díaz Araya, Guillermo; Valenzuela, Rodrigo; Vergara, I.; Corbalán, Ramón; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2005-02-01)
      Meeting Abstract
    • Efectos del carvedilol en la capacidad funcional, función ventricular izquierda, catecolaminas y estrés ... 
      Castro, Pablo; Pérez, Osvaldo; Greig, Douglas; Díaz Araya, Guillermo; Moraga, Francisco; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Padilla, Ivonne; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Lavandero González, Sergio (Sociedad Española de Cardiología, 2004)
      El carvedilol es un antagonista adrenérgico con acción antioxidante y un demostrado beneficio sobre la mortalidad en insuficiencia cardíaca (IC). El objetivo de este estudio es evaluar, en pacientes con insuficiencia ...
    • Effects of atorvastatin therapy in heart failure: Oxidative stress, inflammation, endothelial dysfunction ... 
      Miranda, Rodrigo; Castro, Pablo; Verdejo, Hugo; Greig, Douglas; Alcaíno Olivares, Hernán Alejandro; Bustos Contreras, Carlos Andrés; Vukasovic Ramírez, José Luis; Godoy, Iván; Díaz Araya, Guillermo; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2007-03-06)
      Meeting Abstract
    • Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress ... 
      Castro, Pablo; Pérez, Osvaldo; Greig, Douglas; Díaz Araya, Guillermo; Moraga, Francisco; Chiong Lay, Mario; Troncoso, Rodrigo; Padilla, Ivonne; Vukasovic, Jose L.; Corbalán, Ramón; Lavandero González, Sergio (Ediciones Doyma, S.L., 2004)
      Introduction and objective. Carvedilol is an antioxidant and adrenergic antagonist with demonstrated benefits in terms of mortality from heart failure (HF). The aim of the present study was to evaluate clinical parameters, ...
    • Effects of carvedilol on oxidative stress and chronotropic response to exercise in patients with chronic ... 
      Castro, Pablo; Mc-Nab, Pablo; Quintana, Juan Carlos; Bittner, Alex; Greig, Douglas; Vergara, Ismael; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Copaja, Miguel; Díaz Araya, Guillermo; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Alcaíno Gálvez, Hernán Alejandro; Lavandero González, Sergio (ELSEVIER SCIENCE BV, 2005-10)
      Background: Our previous studies suggest that the increase in heart rate from rest to peak exercise is reduced in patients with chronic heart failure (CHF) and this is associated with increased oxidative stress, as determined ...
    • Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure 
      Castro, Pablo; Mac Nab, Paul; Quintana, Juan Pablo; Bittner, Alex; Greig, Douglas; Vergara, I.; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Copaja, Miguel; Díaz Araya, Guillermo; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Alcaíno Olivares, Hernán Alejandro; Lavandero González, Sergio (EXCERPTA MEDICA INC, 2005-07-15)
      Radionuclide isotopic ventriculography with phase analysis was performed in 30 patients with stable heart failure (HF), determining left ventricular (LV) and interventricular contraction synchrony at baseline and after 6 ...
    • Effects of early decrease in oxidative stress after medical therapy in patients with class IV congestive ... 
      Castro, Pablo; Díaz Araya, Guillermo; Nettle Danniels, Maurice; Corbalán, Ramón; Pérez, Osvaldo; Nazzal Nazal, Carolina; Larrain, Germán; Lavandero González, Sergio (EXCERPTA MEDICA INC, 2002-01-15)
      It has been reported that patients with congestive heart failure (CHF) have increased breath pentane content, conjugated diene levels, and plasma malondialdehyde (MDA) levels, an indirect marker of lipid peroxidation.(1-3) ...
    • Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular ... 
      Ocaranza, María Paz; Godoy, Iván; Jalil Milad, Jorge; Varas, Manuel; Collantes, Patricia; Pinto, Melissa; Román, Maritza; Ramírez, Cristián; Copaja, Miguel; Díaz Araya, Guillermo; Castro, Pablo; Lavandero González, Sergio (LIPPINCOTT WILLIAMS & WILKINS, 2006-10)
      The early and long-term effects of coronary artery ligation on the plasma and left ventricular angiotensin-converting enzyme (ACE and ACE2) activities, ACE and ACE2 mRNA levels, circulating angiotensin (Ang) levels [Ang ...
    • Frailty in patients admitted to hospital with acute decompensated heart failure Factores asociados a ... 
      Díaz-Toro, Felipe; Nazzal Nazal, Carolina; Verdejo, Hugo; Rossel, Víctor; Castro, Pablo; Larrea, Ricardo; Concepción, Roberto; Sepúlveda, Luis; Sepúlveda, Luis (Sociedad Medica de Santiago, 2017)
      © 2017 Rev Med Chile. All right reserved. Background: Frailty is a geriatric syndrome characterized by a progressive impairment in the subjects’ ability to respond to environmental stress. Frailty is more commonly found ...
    • Galectina-3: experiencia en pacientes chilenos con diagnóstico de insuficiencia cardíaca descompensada 
      Rossel Mariángel, Víctor; Díaz Toro, Felipe; Verdejo, Hugo; Concepción, Roberto; Sepúlveda, Luis; Castro, Pablo; Vukasovic, José Luis; Bernales, Angie; Bernales, Angie (Sociedad Medica de Santiago, 2017)
      Background: Galectin-3 (Gal-3) is a mediator of myocardial fibrosis involved in cardiac remodeling and a potential new prognosis marker in heart failure (HF). Aim: To measure Gal-3 at the moment of discharge in patients ...
    • Gln(27)-> Glu beta(2)-Adrenergic Receptor Polymorphism in Heart Failure Patients: Differential Clinical and ... 
      Troncoso Cotal, Rodrigo; Moraga, Francisco; Chiong Lay, Mario; Roldán S., Juan; Bravo Méndez, Roberto; Valenzuela, Rodrigo; Díaz Araya, Guillermo; Campo Sfeir, Andrea Estefanía del; Sanhueza Muñoz, Carlos Joaquín; Rodríguez Villarroel, Andrea Elizabeth; Vukasovic Ramírez, José Luis; Mellado, Rose Marie; Greig, Douglas; Castro, Pablo; Lavandero González, Sergio (WILEY-BLACKWELL PUBLISHING, 2009-05)
      We investigated the clinical response of chronic heart failure patients with beta(2)- adrenergic receptor Gln(27)-> Glu polymorphism treated for 6 months with carvedilol, a alpha/beta-antagonist with antioxidant properties. ...
    • Heart energy metabolism and its role in the treatment of heart failure Metabolismo energético del corazón ... 
      Castro, Pablo; Gabrielli, Luigi; Verdejo, Hugo; Greig, Douglas; Mellado, Rosemarie; Concepción, Roberto; Sepulveda, Luis; Vukasovic, José Luis; García Nannig, Lorena; Pizarro, Marcela; Pivet, Deisy; Carrillo, Constanza; Tapia, Fabiola; Navarro, Mario; Troncoso, Rodrigo; Baraon (2010)
      It is unknown why heart failure progresses even when patients are treated with the best therapy available. Evidences suggest that heart failure progression is due to loss of neurohumoral blockade in advanced stages of the ...
    • Incidencia e importancia pronóstica del deterioro de la función renal en pacientes hospitalizados con ... 
      Castro, Pablo; Verdejo, Hugo; Altamirano, Rodrigo; Downey, Patricio; Vukasovic, José Luis; Sepúlveda Jaqui, Luis; Lanas, Fernando; Bilbao, Paola; Pacheco, Ricardo; Rossel Mariángel, Víctor (Sociedad Médica de Santiago, 2013)
      Background: Acute deterioration of kidney function among patients admitted to the hospital for cardiac failure is associated with an increased mortality. Aim: To investigate the association between deterioration of kidney ...
    • Inflamación y disfunción endotelial en pacientes con insuficiencia cardiaca crónica 
      Greig, Douglas; Castro, Pablo; Gabrielli, Luigi A.; Miranda, Rodrigo; Verdejo, Hugo; Alcaíno Gálvez, Hernán Alejandro; Bustos, Carlos; Chiong Lay, Mario; Godoy, Iván; Mellado, Rose Marie; García Nannig, Lorena; Salas, Daniela; Vivar Sánchez, Raúl; Vukasovic Ramírez, José Luis; Concepción, Roberto; Díaz Araya, Guillermo (SOC MEDICA SANTIAGO, 2008-06)
      Background: In chronic heart failure (CHF), endothelial dysfunction (ED) is a consequence of an imbalance of vascular tone regulating substances. The relationship between ED and inflammation has not been fully investigated. ...
    • Inflammation and endothelial dysfunction in patients with chronic heart failure Inflamación y disfunción ... 
      Greig, Douglas; Castro, Pablo; Gabrielli, Luigi; Miranda, Rodrigo; Verdejo, Hugo; Alcaíno Gálvez, Hernán Alejandro; Bustos, Carlos; Chiong Lay, Mario; Godoy, Iván; Mellado, Rosemarie; García Nannig, Lorena; Salas, Daniela; Vivar, Raúl; Vukasovic, José Luis; Concepción, Roberto; Díaz Araya, Guillermo (2008)
      Background: In chronic heart failure (CHF), endothelial dysfunction (ED) is a consequence of an imbalance of vascular tone regulating substances. The relationship between ED and inflammation has not been fully investigated. ...
    • Interacción entre los polimorfismos del receptor ß1 y ß2 adrenérgico como predictor de riesgo de insuficiencia ... 
      Moraga, Francisco; Troncoso, Rodrigo; Mellado, Rose Marie; Díaz Araya, Guillermo; Vukasovic Ramírez, José Luis; Greig, Douglas; Pérez, Osvaldo; García Nannig, Lorena; Roldán, Juan; Ocaranza, María Paz; Jalil Milad, Jorge; Chiong Lay, Mario; Castro, Pablo (SOC MEDICA SANTIAGO, 2008-11)
      Background: beta adrenergic receptors (AR) are highly polymorphic and important regulators of cardiovascular homeostatis. Among these, beta(1) and beta(2) AR regulate cardiac contractility and frequency and are important ...
    • Interactions between ß 1 and ß 2 adrenergic receptor polymorphisms as risk factors for chronic heart failure ... 
      Moraga, Francisco; Troncoso, Rodrigo; Mellado, Rosemarie; Díaz Araya, Guillermo; Vukasovic, José Luis; Greig, Douglas; Pérez, Osvaldo; García Nannig, Lorena; Roldán, Juan; Ocaranza, María Paz; Jalil Milad, Jorge; Chiong Lay, Mario; Castro, Pablo (2008)
      Background: ß adrenergic receptors (AR) are highly polymorphic and important regulators of cardiovascular homeostasis. Among these, ß1 and ß2 AR regulate cardiac contractility and frequency and are important pharmacological ...
    • Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure 
      Ocaranza, María Paz; Gabrielli, Luigi; Mora, Italo; García Nannig, Lorena; McNab, Paul; Godoy, Iván; Braun, Sandra; Córdova, Samuel; Castro, Pablo; Novoa, Ulises; Chiong Lay, Mario; Lavandero González, Sergio; Jalil, E. (MOSBY-ELSEVIER, 2011-05)
      Background The small guanosine triphosphatase Rho and its target Rho-kinase have significant roles in experimental remodeling and ventricular dysfunction, but no data are available on Rho-kinase activation in patients with ...
    • Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca 
      Castro, Pablo; Gabrielli, Luigi A.; Verdejo, Hugo; Greig, Douglas; Mellado, Rose Marie; Concepción, Roberto; Sepúlveda Morales, Luis; Vukasovic Ramírez, José Luis; García Nannig, Lorena; Pizarro, Marcela; Pivet, Deisy; Carrillo, Constanza; Tapia, Fabiola; Navarro, Mario; Troncoso, Rodrigo; Baraona, Fernando; Llevaneras, Silvana; Hernández, Claudia; Godoy, Iván; Jalil Milad, Jorge; Quintana, Juan Carlos; Orellana, Pilar; Chiong Lay, Mario; Lavandero González, Sergio (SOC MEDICA SANTIAGO, 2010-08)
      It is unknown why heart failure progresses even when patients are treated with the best therapy available. Evidences suggest that heart failure progression is due to loss of neurohumoral blockade in advanced stages of the ...