Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure
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2005-07-15Metadatos
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Castro, Pablo
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Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure
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Radionuclide isotopic ventriculography with phase analysis was performed in 30 patients with stable heart failure (HF), determining left ventricular (LV) and interventricular contraction synchrony at baseline and after 6 months of treatment with maximal tolerated doses of carvedilol. Patients with HF had significant ventricular dyssynchrony compared with a normal population. The 50th percentile of patients with the greatest dyssynchrony at baseline showed significant improvement in ventricular synchrony after receiving carvedilol, and this was correlated positively with a reduction in end-diastolic LV volumes.
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AMERICAN JOURNAL OF CARDIOLOGY 96(2): 267-269
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