Browsing by Author "Cerda Arancibia, Oscar Alejandro"

Now showing items 1-8 of 8

    • “Analysis of the regulation of the expression of Kv1.2 potassium channel” 
      Venegas Zúñiga, Nataly Belén (Universidad de Chile, 2022)
      Neuron excitability is one of the most relevant functions in the nervous system and is controlled by voltage-gated ion channels. Voltage-gated potassium channels 1 (Kv1) are critical to maintaining membrane potential ...
    • Identificación y caracterización del proteoma involucrado en la regulación de la entrada de calcio operada ... 
      Santos Alfaro, Rodrigo Alejandro (Universidad de Chile, 2023)
      La entrada de Ca2+ operada por reservorios internos (SOCE) es el mecanismo principal para regular las señales de Ca2+ en células no excitables. Las proteínas STIM1, ORAI1 y SARAF participan en SOCE, que median este mecanismo ...
    • Participación del canal iónico TRPC6 en la regulación de la actividad del factor transcripcional YAP mediante ... 
      Lavanderos Andrade, Boris Joan (Universidad de Chile, 2022)
      La contractilidad celular es un mecanismo implicado en diversos procesos celu- lares como la cicatrización de heridas y la contracción arterial, entre otros. La actividad de los canales iónicos se ha asociado con la ...
    • PPI-MASS: an interactive web server to identify protein-protein interactions from mass spectrometry-based ... 
      González Avendaño, Mariela; Zúñiga Almonacid, Simón Felipe; Silva, Ian; Lavanderos, Boris; Robinson, Felipe; Rosales Rojas, Roberto; Durán Verdugo, Fabio; González, Wendy; Cáceres Lluch, Mónica; Cerda Arancibia, Oscar Alejandro; Vergara Jaque, Ariela (Frontiers Media, 2021)
      Mass spectrometry-based proteomics methods are widely used to identify and quantify protein complexes involved in diverse biological processes. Specifically, tandem mass spectrometry methods represent an accurate and ...
    • The cytoplasmic region of SARAF reduces triple-negative breast cancer metastasis through the regulation of ... 
      Saldías Maulén, María Paz; Cruz Núñez, Pablo; Silva Del Canto, Ian; Orellana Serradell, Octavio Andrés; Lavanderos Andrade, Boris Joan; Maureira Fuentes, Diego Javier; Pinto Sierralta, Raquel Cristina; Cerda Arancibia, Oscar Alejandro (MDPI, 2023)
      Triple-negative breast cancer has a poor prognosis and is non-responsive to first-line therapies; hence, new therapeutic strategies are needed. Enhanced store-operated Ca2+ entry (SOCE) has been widely described as a ...
    • TRP channels interactome as a novel therapeutic target in breast cancer 
      Saldías Maulén, María Paz; Maureira Fuentes, Diego Javier; Orellana Serradell, Octavio Andrés; Silva del Canto, Ian; Lavanderos Andrade, Boris Joan; Cruz, Pablo; Torres Paredes, Camila Esperanza; Cáceres Lluch, Mónica; Cerda Arancibia, Oscar Alejandro (MDPI, 2021)
      Breast cancer is one of the most frequent cancer types worldwide and the first cause of cancer-related deaths in women. Although significant therapeutic advances have been achieved with drugs such as tamoxifen and trastuzumab, ...
    • TRPM4 Expression during postnatal developmental of mouse CA1 pyramidal neurons 
      Riquelme, Denise; Cerda Arancibia, Oscar Alejandro; Leiva Salcedo, Elías (Frontiers Media, 2021)
      TRPM4 is a non-selective cation channel activated by intracellular calcium and permeable to monovalent cations. This channel participates in the control of neuronal firing, neuronal plasticity, and neuronal death. TRPM4 ...
    • VAPA es una proteína que interactúa y regula la actividad del canal TRPC6 
      Torres Yévenez, Camila Andrea (Universidad de Chile, 2022)
      El cáncer de mama es uno de los tipos de cáncer diagnosticados con mayor frecuencia a nivel mundial y la primera causa de muerte asociada a cáncer entre las mujeres. Diversos estudios han demostrado que la progresión del ...