Browsing by Author "Chaparro, Alejandra"

Now showing items 1-10 of 10

    • Active MMP-8 quantitative test as an adjunctive tool for early diagnosis of periodontitis 
      Hernández Ríos, Marcela; Baeza Paredes, Mauricio Enrique; Raisanen, Ismo; Contreras Balbontín, Johanna; Tervahartiala, Taina; Chaparro, Alejandra; Sorsa, Timo; Hernández Ríos, Patricia (MDPI, 2021)
      Periodontitis is a host-mediated bacterial disease that affects the tooth attachment apparatus. Metalloproteinase-8 (MMP-8), a validated biomarker, could aid in clinical diagnosis. This study aimed to evaluate the diagnostic ...
    • CpG single-site methylation regulates tlr2 expression in proinflammatory PBMCs from apical periodontitis ... 
      Bordagaray San Martín, María José; Fernández, Alejandra; Astorga, Jessica; Garrido Flores, Carlos Mauricio; Hernández Ríos, Patricia; Chaparro, Alejandra; Lira, María Jesús; Gebicke Haerter, Peter; Hernández Ríos, Emma (Frontiers Media, 2022)
      IntroductionApical periodontitis (AP) is a common oral disease caused by the inflammatory destruction of the periapical tissues due to the infection of the root canal system of the tooth. It also contributes to systemic ...
    • Detection of Porphyromonas gingivalis in the amniotic fluid in pregnant women with a diagnosis of threatened ... 
      León Berríos, Rubén; Silva Steffens, Nora; Ovalle Salas, Víctor; Chaparro, Alejandra; Ahumada, Alexis; Gajardo, Marta; Martínez, María José; Gamonal Aravena, Jorge Antonio (2007)
      Background: Epidemiologic and randomized controlled studies have shown that periodontal diseases may be associated with preterm labor and delivery of infants with low birth weights. The purpose of the present study was to ...
    • Diagnóstico de preeclampsia basado en biomarcadores angiogenicos placentarios presentes en el fluido gingival ... 
      Albers Busquets, Daniela (Universidad de Chile, 2017)
      La preeclampsia (PE) es una enfermedad de causa desconocida, multifactorial y multiorgánica del embarazo. Los exosomas, considerados biomarcadores, pueden ser aislados del fluido gingival crevicular (FGC), y son capaces ...
    • Exploring the expression of pro-inflammatory and hypoxia-related microRNA-20a, MicroRNA-30e, and microRNA-93 ... 
      Chaparro, Alejandra; Lozano, Mauricio; Gaedechens, Dominique; López, Carolina; Albers, Daniela; Hernández Ríos, Emma Marcela; Pascual, Andrés; Nart, José; Irarrazabal, Carlos E. (MDPI, 2022)
      Hypoxia associated with inflammation are common hallmarks observed in several diseases, and it plays a major role in the expression of non-coding RNAs, including microRNAs (miRNAs). In addition, the miRNA target genes for ...
    • Gingival crevicular placental alkaline phosphatase is an early pregnancy biomarker for pre-eclampsia 
      Chaparro, Alejandra; Monckeberg, Maximiliano; Realini, Ornella; Hernández Ríos, Emma Marcela; Param Agurto, Maria Fernanda; Albers Busquets, Daniela; Ramírez, Valeria; Kusanovic Pivcevic, Juan Pedro; Romero, Roberto; Rice, Gregory; Illanes, Sebastián E. (MDPI, 2021)
      Early and innovative diagnostic strategies are required to predict the risk of developing pre-eclampsia (PE). The purpose of this study was to evaluate the performance of gingival crevicular fluid (GCF) placental alkaline ...
    • Levels of interleukin-17 in gingival crevicular fluid and in supernatants of cellular cultures of gingival ... 
      Vernal Astudillo, Rolando; Dutzan Muñoz, Nicolás; Chaparro, Alejandra; Puente Piccardo, Javier; Valenzuela, María Antonieta; Gamonal Aravena, Jorge Antonio (BLACKWELL MUNKSGAARD, 2005-04)
      Background and Aims: Interleukin-17 (IL-17) is a T-cell-derived cytokine that may play an important role in the initiation or maintenance of the pro-inflammatory response and has recently been found to stimulate osteoclastic ...
    • Periodontitis and gestational diabetes mellitus: a potential inflammatory vicious cycle 
      Bendek, María José; Canedo Marroquín, Gisela; Realini, Ornella; Retamal, Ignacio N.; Hernández Ríos, Emma; Hoare Teuche, Anilei Paz; Busso, Dolores; Monteiro, Lara J.; Illanes, Sebastián E.; Chaparro, Alejandra (MDPI, 2021)
      Periodontitis is a chronic inflammatory immune disease associated with a dysbiotic state, influenced by keystone bacterial species responsible for disrupting the periodontal tissue homeostasis. Furthermore, the severity ...
    • Relación entre enfermedad periodontal, infección bacteriana ascendente y patología placentaria con parto prematuro 
      Ovalle, Alfredo; Gamonal Aravena, Jorge Antonio; Martínez, M. Angélica; Silva Steffens, Nora; Kakarieka, Elena; Fuentes García, Frans; Chaparro, Alejandra; Gajardo, Marta; León Berríos, Rubén; Ahumada, Alexis; Cisternas, Carlos (Sociedad Médica de Santiago, 2009-04)
      Background: There is an association between periodontal diseases and preterm delivery. Aim: To assess the relationship between periodontal diseases, ascending bacterial infection and placental pathology with preterm delivery. ...
    • Stimulatory response of neutrophils from periodontitis patients with periodontal pathogens 
      Restaino Bianchi, Carmen Gloria; Chaparro, Alejandra; Valenzuela, María Antonieta; Kettlun, Ana María; Vernal Astudillo, Rolando; Silva, A.; Puente Piccardo, Javier; Jaque, M. P.; León Berríos, Rubén; Gamonal Aravena, Jorge Antonio (2007)
      OBJECTIVE: Neutrophils play a crucial role in the defense of invading bacteria by releasing biologically active molecules. The response of peripheral blood neutrophils was studied in periodontitis-affected patients and in ...