Browsing by Author "Cuchacovich Turteltaub, Miguel"
Now showing items 1-20 of 27
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(1994)This work describes a new method to detect antimitochondrial antibodies using indirect immunofluorescence on mouse sperm as substrate. As controls conventional substrates and mitochondrial protein immunoblots were used. ...
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(2005)Objective. To assess the enzymatic activity and biochemical status of dipeptidyl peptidase IV (DPP IV), an enzyme that participates in the degradation of proinflammatory molecules, in sera from a group of patients with ...
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(2008)Purpose: To evaluate the role of azathioprine as an immunosuppressive for steroid-resistant autoimmune uveitis (AIU). Methods: Patients using oral prednisolone for active AIU without clinical response were recruited. A ...
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(2010)Introduction: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory ...
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(Elsevier, 2015)Autoantibodies from autistic spectrum disorder (ASD) patients react with multiple proteins expressed in the brain. One such autoantibody targets myelin basic protein (MBP). ASD patients have autoantibodies to MBP of both ...
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Clinical parameters and biomarkers for anti-TNF treatment prognosis in rheumatoid arthritis patients (International League of Associations for Rheumatology (ILAR), 2014)Tumor necrosis factor (TNF) plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA). This finding has led to the development of TNF blockers for RA treatment. However, response to these therapies is ...
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(ELSEVIER, 2006)Tumour necrosis factor (TNF), a cytokine mainly produced by macrophages, is associated with a broad spectrum of biological effects, mainly associated with the host defense against microbes. The TNF gene Is located on ...
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(Sociedad Médica de Santiago, 2007)Background: Topical and systemic steroids are the first line of treatment of non infectious inflammatory ocular disease. Immunosuppresants are reserved as a second line treatment. Aim: To evaluate the role of Azathioprine ...
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(SOC MEDICA SANTIAGO, 2006-07)The efficacy and safety of repeated administration of infliximab was evaluated in five patients (two men, three women) with Behcet syndrome accompanied by severe uveoretinitis. Ocular and extra ocular inflammation was ...
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(Sociedad Médica de Santiago, 2009)Background: Behçet’s disease (BD) is a rare multisystemic inflammatory disease that is potentially disabling and may cause death. Aim: To describe the characteristics of BD patients from two Chilean centers. Patients and ...
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(Future Medicine Ltd., 2015)
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(SPRINGER, 2008-04)SAPHO syndrome is a rare entity that compromises the skeletal system (arthritis-osteitis) and is associated with various dermatological conditions such as palmoplantaris pustulosis (PPP) and acne. We present the case of a ...
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(1991)We analyzed the results of bronchoalveolar lavage (BAL) in 14 patients with Rheumatoid Arthritis. Ten patients had total cell counts above 10 x 10(6)/100 ml and or more than 10% lymphocytes in differential counts. 40% of ...
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(1988)The antiinflammatory effect of a single intraarticular injection of progesterone was investigated in 12 patients with rheumatoid arthritis. A local, but no systemic decline of inflammation was observed in 10 of them for ...
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(Sociedad de Biología de Chile, 2005)Longitudinal studies aimed at evaluating patients clinical response to specific therapeutic treatments are frequently summarized in incomplete datasets due to missing data. Multivariate statistical procedures use only ...
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(Mary Ann Liebert, 2016)Purpose: To study the efficacy and incidence of treatment-related side effects of mycophenolate mofetil (MMF) therapy in patients with noninfectious inflammatory eye diseases. Methods: Retrospective cohort study of 27 ...
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(1991)Neurologic involvements is a rare complication of Reiter syndrome. It may precede other manifestations and constitutes a cause of death. We report 2 cases. The first, an 18 year-old male developed arthritis, fever, balanitis ...
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(Sociedad Médica de Santiago, 2003)The fusion of a murine B cell and a myeloma cell generates a hybridoma that produces monoclonal antibody (mAb). These murine mAb induce the HAMA (human anti-mouse antibodies) response. Murine mAb have been modified by ...
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(Sociedad Médica de Santiago, 2005)Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects 0.8% of the world population, it affects the synovial membrane of joints and the clinical presentation encompasses a wide spectrum, ranging from a ...
