Browsing by Author "Díaz Espinoza, Rodrigo"

Now showing items 1-4 of 4

    • Catalytic amyloids as novel synthetic hydrolases 
      Durán Meza, Eva Lisa; Díaz Espinoza, Rodrigo (MDPI, 2021)
      Amyloids are supramolecular assemblies composed of polypeptides stabilized by an intermolecular beta-sheet core. These misfolded conformations have been traditionally associated with pathological conditions such as Alzheimer's ...
    • Development of a novel catalytic amyloid displaying a metal-dependent ATPase-like activity 
      Monasterio Opazo, Octavio; Nova Martínez, Esteban; Díaz Espinoza, Rodrigo (Elsevier B.V., 2017)
      Amyloids are protein aggregates of highly regular structure that are involved in diverse pathologies such as Alzheimer's and Parkinson's disease. Recent evidence has shown that under certain conditions, small peptides can ...
    • Domain folding and flexibility of Escherichia coli FtsZ determined by tryptophan site-directed mutagenesis 
      Díaz Espinoza, Rodrigo; Garcés, Andrea P.; Arbildua, José J.; Montecinos, Felipe; Brunet, Juan E.; Lagos Mónaco, Rosalba; Monasterio Opazo, Octavio (COLD SPRING HARBOR LAB PRESS, 2007-08)
      FtsZ has two domains, the amino GTPase domain with a Rossmann fold, and the carboxyl domain that resembles the chorismate mutase fold. Bioinformatics analyses suggest that the interdomain interaction is stronger than the ...
    • Molecular Cross Talk between Misfolded Proteins in Animal Models of Alzheimer’s and Prion Diseases 
      Morales, Rodrigo; Estrada, Lisbell D.; Díaz Espinoza, Rodrigo; Morales Scheihing, Diego; Jara, María C.; Castilla, Joaquín; Soto, Claudio (2010-03-31)
      The central event in protein misfolding disorders (PMDs) is the accumulation of a misfolded form of a naturally expressed protein. Despite the diversity of clinical symptoms associated with different PMDs, many similarities ...