Browsing by Author "Echeverría, César"

Now showing items 1-5 of 5

    • Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor ... 
      Echeverría, César; Montorfano, Ignacio; Hermosilla, Tamara; Armisen Yáñez, Ricardo; Velásquez, Luis A.; Caballero Verrugio, Claudio; Varela Lekanda, Diego; Simón, Felipe (PLOS One, 2014)
      The pathogenesis of systemic inflammatory diseases, including endotoxemia-derived sepsis syndrome, is characterized by endothelial dysfunction. It has been demonstrated that the endotoxin lipopolysaccharide (LPS) induces ...
    • Human peritoneal mesothelial cell death induced by high-glucose hypertonic solutioninvolves Ca2+ and Na+ ... 
      Simon, Felipe; Tapia, Pablo; Armisen Yáñez, Ricardo; Echeverría, César; Gatica, Sebastián; Vallejos, Alejandro; Pacheco Durán, Alejandro; Sanhueza Villanueva, María Eugenia; Alvo Abodovsky, Miriam; Segovia, Erico; Torres, Rubén (Frontiers Media, 2017)
      Chronic peritoneal dialysis (PD) therapy is equally efficient as hemodialysis while providing greater patient comfort and mobility. Therefore, PD is the treatment of choice for several types of renal patients. During PD, ...
    • Structural antitumoral activity relationships of synthetic chalcones 
      Echeverría, César; Santibáñez, Juan Francisco; Donoso Tauda, Óscar; Escobar, Carlos A.; Ramírez Tagle, Rodrigo (2009)
      Relationships between the structural characteristic of synthetic chalcones and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with synthetic 2'-hydroxychalcones resulted in apoptosis induction ...
    • TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of ... 
      Sagredo, Alfredo I.; Sagredo, Eduardo A.; Pola, Victor; Echeverría, César; Andaur, Rodrigo; Michea Acevedo, Luis; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisén, Ricardo (Wiley, 2019)
      Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐ dependent monovalent cation channel, which depolarizes the plasma cell membrane, thereby modulating Ca2+ influx across Ca2+‐permeable ...
    • TRPM4 regulates Akt/GSK3-b activity and enhances b-catenin signaling and cell proliferation in prostate ... 
      Sagredo, A.; Sagredo, Eduardo A.; Cappelli, Claudio; Baez, Pablo; Andaur, Rodrigo E.; Blanco, Constanza; Tapia, Julio C.; Echeverría, César; Cerda, Oscar; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo (John Wiley, 2018)
      Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing ...