Browsing by Author "Escobar, Alejandro"

Now showing items 1-13 of 13

    • A synthetic peptide homologous to functional domain of human IL-10 down-regulates expression of MHC class ... 
      Kurte, Mónica; López, Mercedes; Aguirre, Adam; Escobar, Alejandro; Aguillón Gutiérrez, Juan Carlos; Charo, Jehad; Larsen, Christian G.; Kiessling, Rolf; Salazar Onfray, Flavio (American Association of Immunologists, 2004)
      Tumor cells treated with IL-10 were shown to have decreased, but peptide-inducible expression of MHC class I, decreased sensitivity to MHC class I-restricted CTL, and increased NK sensitivity. These findings could be ...
    • An anti-human recombinant tumor necrosis factor alpha (TNFα) monoclonal antibody recognizes an epitope in ... 
      Aguirre, Adam; Escobar, Alejandro; Ferreira, Viviana; Molina, María C.; Ferreira, Arturo; Aguillón Gutiérrez, Juan Carlos (EDP Sciences, 2003)
      It is likely that the murine response to human recombinant TNFα (hrTNFα) may generate antibodies (Ab) to epitopes present in TNFα from other species. Here, we demonstrate that F5 anti-hrTNFα monoclonal antibody (mAb) ...
    • ATP Induces IL-1 β Secretion in Neisseria gonorrhoeae-Infected Human Macrophages by a Mechanism Not Related ... 
      Garciá, Killen; Escobar, Gisselle; Mendoza, Pablo; Beltran, Caroll; Pérez, Claudio; Arancibia, Sergio; Vernal Astudillo, Rolando; Rodas, Paula; Acunã-Castillo, Claudio; Escobar, Alejandro (Hindawi Limited, 2016)
      Neisseria gonorrhoeae (Ngo) has developed multiple immune evasion mechanisms involving the innate and adaptive immune responses. Recent findings have reported that Ngo reduces the IL-1𝛽 secretion of infected human ...
    • Bovine fetal mesenchymal stem cells exert antiproliferative effect against mastitis causing pathogen ... 
      Cahuascanco, Berly; Bahamonde, Javiera; Huaman, Olger; Jervis, Miguel; Cortez, Jahaira; Palomino, Jaime; Escobar, Alejandro; Retamal Merino, Patricio; Torres, Cristian G.; Peralta, Óscar Alejandro (BioMed Central, 2019)
      Staphylococcus aureus is the most commonly isolated pathogen from clinical bovine mastitis samples and a difficult pathogen to combat. Mesenchymal stem cells (MSC) are multipotent progenitor cells equipped with a variety ...
    • Caracterización funcional de la proteína factor acelerador del decaimiento de tripomastigotes de trypanosoma ... 
      Elgueta Reyes, Bastián Nicolás (Universidad de Chile, 2021)
      RESUMEN Trypanosoma cruzi es un parásito protozoario y es el agente causal de la enfermedad de Chagas. Su ciclo de vida, transcurre entre un vector invertebrado y un hospedero vertebrado. Dentro de este último, T. cruzi ...
    • Gastrointestinal Bleeding of the Jejunojejunostomy in Laparoscopic Roux En Y Gastric Bypass, Is It Preventable? 
      Saba, Jorge; Bravo, Magdalena; Escobar, Alejandro; Muñoz, Juan; Zajjur, Jorge (Springer, 2015)
    • In vivo antitumor effect against murine cells of CT26 colon cancer and EL4 lymphoma by autologous whole ... 
      Barrera Ávalos, Carlos Esteban; Díaz, Ximena; Madrid, Sebastián; Michelson, Sofía A.; Robles Planells, Claudia Julieta; Sánchez Guerrero, Giselle; Ahumada, Viviana; Mella Torres, Andrea Jesús; Rojo, Leonel E.; Imarai Bahamonde, Mónica; Milla, Luis A.; Leiva Salcedo, Elías; Murgas, Paola; Fernández, Ricardo; Escobar, Alejandro; Acuña Castillo, Claudio (Hindawi, 2021)
      Active immunotherapy against cancer is based on immune system stimulation, triggering efficient and long-lasting antigen-specific immune responses. Immunization strategies using whole dead cells from tumor tissue, containing ...
    • Lipopolysaccharide inhibits the channel activity of the P2X7 receptor 
      Leiva Salcedo, Elías; Coddou, Claudio; Rodríguez, Felipe; Penna, Antonello; López, Ximena; Neira, Tanya; Fernández, Ricardo; Imarai, Mónica; Rios, Miguel; Escobar, Jorge; Montoya, Margarita; Huidobro Toro, Juan; Escobar, Alejandro; Acuña Castillo, Claudio (2011)
      The purinergic P2X7 receptor (P2X7R) plays an important role during the immune response, participating in several events such as cytokine release, apoptosis, and necrosis. The bacterial endotoxin lipopolysaccharide (LPS) ...
    • Long-Term Results of Laparoscopic Roux En Y Gastric Bypass as a Primary Procedure 
      Saba, Jorge; Bravo, Magdalena; Escobar, Alejandro; Torres, Macarena; Zajjur, Jorge; Muñoz, Juan (Springer, 2015)
    • Neisseria gonorrhoeae Modulates Immunity by Polarizing Human Macrophages to a M2 Profile 
      Ortiz, María Carolina; Lefimil Puente, Claudia; Rodas, Paula I.; Vernal Astudillo, Rolando; López, Mercedes; Acuña Castillo, Claudio; Imarai, Mónica; Escobar, Alejandro (Public Library Science, 2015)
      Current data suggest that Neisseria gonorrhoeae is able to suppress the protective immune response at different levels, such as B and T lymphocytes and antigen-presenting cells. The present report is focused on gonococcus ...
    • Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-specific delayed ... 
      López, Mercedes N.; Pereda, Cristian; Segal, Gabriela; Muñoz, Leonel; Aguilera, Raquel; González, Fermín E.; Escobar, Alejandro; Ginesta, Alexandra; Reyes, Diego; González, Rodrigo; Mendoza Naranjo, Ariadna; Larrondo, Milton; Compán, Alvaro; Ferrada, Carlos; Salazar Onfray, Flavio (2009)
      Purpose The aim of this work was to assess immunologic response, disease progression, and posttreatment survival of melanoma patients vaccinated with autologous dendritic cells (DCs) pulsed with a novel allogeneic cell ...
    • Serum from aged F344 rats conditions the activation of young macrophages 
      Gómez, Christian; Acuña Castillo, Claudio; Nishimura, Sumiyo; Pérez, Viviana; Escobar, Alejandro; Salazar Onfray, Flavio; Sabaj Diez, Valeria; Torres, Claudio; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2006-03)
      There is considerable controversy about the molecular mechanisms responsible for the variations in innate immunity associated with age. While in vivo, aged animals and humans react to an inflammatory signal with ail excessive ...
    • α-2-macroglobulin in saliva is associated with glycemic control in patients with type 2 diabetes mellitus 
      Aitken, Juan; Ortiz, Carolina; Morales Bozo, Irene; Rojas Alcayaga, Gonzalo; Baeza, Mauricio; Beltran, Caroll; Escobar, Alejandro (Hindawi Limited, 2015)
      © 2015 Juan Pablo Aitken et al.Background. Subjects with type 2 diabetes mellitus (DM2) require an adequate glycemic control to avoid diabetic complications. Currently, saliva biomarkers are used as a diagnostic tool and ...