Browsing by Author "Estrada Hormazábal, Manuel"
Now showing items 1-9 of 9
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(MDPI, 2021)Low-grade chronic inflammation plays a pivotal role in the pathogenesis of insulin resistance (IR), and skeletal muscle has a central role in this condition. NLRP3 inflammasome activation pathways promote low-grade chronic ...
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(Universidad de Chile, 2000)
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(SOC ENDOCRINOLOGY, 2005-02)Ca2+ oscillations are one of the most important signals within the cell. The mechanism for generation of Ca2+ oscillations is still not yet fully elucidated. We studied the role of capacitative Ca2+ entry (CCE) on intracellular ...
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(Lippincott Williams & Wilkins, 2008)Altered regulation of signaling pathways can lead to pathologies including cardiac hypertrophy and heart failure. We report that neonatal and adult cardiomyocytes express chromogranin B (CGB), a Ca2+ binding protein that ...
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(Universidad de Chile, 2011)La testosterona es la principal hormona sexual masculina, responsable de múltiples efectos en el organismo. Dentro de estos, se ha descrito que es capaz de producir hipertrofia cardiaca tanto in vitro como in vivo. Una ...
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(American Heart Association, 2013)Rationale: The ability of a cell to independently regulate nuclear and cytosolic Ca2+ signaling is currently attributed to the differential distribution of inositol 1,4,5-trisphosphate receptor channel isoforms in the ...
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(Universidad de Chile, 2011)El uso de elevadas dosis de testosterona produce hipertrofia cardiaca, sin embargo los mecanismos celulares no son completamente entendidos. La proteína quinasa GSK3-β (glycogen synthase kinase 3-β) es una quinasa que ...
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(Universidad de Chile, 2011)La testosterona, a través de aumentos del Ca2+ intracelular mediado por el receptor para inositol 1,4,5 trifosfato (IP3R), produce hipertrofia del cardiomiocito. La hipertrofia conlleva un cambio metabólico que se asocia ...
