Browsing by Author "Hernández, Alejandro"
Now showing items 1-16 of 16
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Agmatine induces antihyperalgesic effects in diabetic rats and a superadditive interaction with ... Courteix, Christine; Privat, Anne Marie; Pelissier Serrano, Teresa; Hernández, Alejandro; Eschalier, Alain; Fialip, Joseph (AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 2007-09)Agmatine, an endogenous cationic amine resulting from the decarboxylation of L-arginine, produces antihyperalgesic and antiallodynic effects in animal models of chronic neuropathic and inflammatory pain. We examined the ...
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Laurido, Claudio; Hernández, Alejandro; Pelissier Serrano, Teresa; Constandil, Luis (The Scientific World Journal, 2012)N-methyl-D-aspartic acid receptor (NMDAr) activation requires the presence ofD-serine, synthesized from L-serine by a pyridoxal 5 -phosphate-dependent serine racemase (SR). D-serine levels can be lowered by inhibiting the ...
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Sáez Briones, Patricio; Soto Moyano, Rubén; Burgos, Héctor; Castillo, Amparo; Valladares Boasi, Luis; Morgan Sabat, Carlos; Pérez, Hernán; Barra, Rafael; Constandil, Luis; Laurido, Claudio; Hernández, Alejandro (Elsevier, 2015)Moderate reduction in dietary protein composition of pregnant rats from 25% to 8% casein, calorically compensated by carbohydrates, has been described as a ‘‘hidden malnutrition’’ because it does not alter body and brain ...
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Pelissier Serrano, Teresa; Laurido, Claudio; Hernández, Alejandro; Constandil, Luis; Eschalier, Alain (ELSEVIER, 2006-09-28)Studies on the effect of dopaminergic agonists in behavioral measures of nociception have gathered numerous but rather conflicting data. We studied the effects of the D-1/D-2 receptor agonist apomorphine, as well as the ...
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Wattiez, Anne Sophie; Pichon, Xavier; Dupuis, Amandine; Hernández, Alejandro; Privat, Anne Marie; Aissouni, Youssef; Chalus, Maryse; Pelissier Serrano, Teresa; Eschalier, Alain; Marin, Philippe; Courteix, Christine (Plos One, 2013)Despite common pathophysiological mechanisms, inflammatory and neuropathic pain do not respond equally to the analgesic effect of antidepressants, except for selective serotonin reuptake inhibitors (SSRIs), which show a ...
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Hernández, Alejandro; Soto Moyano, Rubén (1986)Bioelectrical responses evoked in the ventrolateral funiculus (VLF) of the spinal cord by electrical stimulation of the contralateral hind limb were studied following topical application of 1% morphine solution to the ...
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Soto Moyano, Rubén; Fernández, Victor; Sanhueza, Miguel; Belmar, Jorge; Kusch, Claudia; Pérez, Hernán; Ruiz, Samuel; Hernández, Alejandro (1999)There is evidence that severe malnutrition started during gestation and continued through lactation affects adversely the morphologic development of the neocortex leading to increased neuronal cell packing density and ...
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González, Héctor; Adaro, Luis; Hernández, Alejandro; Fernández, Víctor (Universidad de la Frontera, 2014)This investigation was undertaken in order to quantify the effects of early polysensorial enrichment on the development of cortical pyramids, located in the parietal cortex of rats simultaneously submitted to protein-energy ...
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Cayupe, Bernardita; Morgan, Carlos; Puentes, Gustavo; Valladares Boasi, Luis Emilio; Burgos, Héctor; Castillo, Amparo; Hernández, Alejandro; Constandil, Luis; Ríos, Miguel; Sáez Briones, Patricio; Barra, Rafael (MDPI, 2021)Prenatally malnourished rats develop hypertension in adulthood, in part through increased alpha(1)-adrenoceptor-mediated outflow from the paraventricular nucleus (PVN) to the sympathetic system. We studied whether both ...
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Pérez,; Ruiz, Daniela; Hernández, Alejandro; Soto Moyano, Rubén (1984)Cortical reactivity of the parietal association area was studied in undernourished rats after short and long rehabilitation periods. Undernutrition was induced during lactation by increasing litter size from 8 to 18 pups ...
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Soto Moyano, Rubén; Burgos, Héctor; Flores, Francisco; Valladares Boasi, Luis; Sierralta, Walter; Fernández Hidalgo, Víctor; Pérez, Hernán; Hernández, Paula; Hernández, Alejandro (PERGAMON-ELSEVIER SCIENCE LTD, 2006-10)Melatonin has been shown to inhibit long-term potentiation (LTP) in hippocampal slices of rats. Since LTP may be one of the main mechanisms by which memory traces are encoded and stored in the central nervous system, it ...
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Sierralta, Walter; Hernández, Alejandro; Valladares Boasi, Luis; Pérez, Hernán; Mondaca, Mauricio; Soto Moyano, Rubén (PERGAMON-ELSEVIER SCIENCE LTD, 2006-05-15)Mild reduction in the protein content in the diet of pregnant rats from 25 to 8% casein, calorically compensated by carbohydrates, does not alter body and brain weights of rat pups at birth, but results in significant ...
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Buttigieg, Angie; Flores, Osvaldo; Hernández, Alejandro; Sáez Briones, Patricio; Burgos, Héctor; Morgan Sabat, Carlos (Elsevier, 2014)Obesity is a worldwide epidemic that is increasing at an alarming rate. One of its causes is the increased availability and consumption of diets rich in fat. In the present study, we investigated the effects of ...
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Hernández, Alejandro; Pérez, Hernán; Ruiz, S.; Soto Moyano, Rubén (Elsevier, 1983)The influence of both reserpine-induced depletion of catecolamines and chlorpromazine-induced blockade of dopamine receptors on integrative properties of rats prefrontal pyramidal cells was studied by evocating threshold ...
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Soto Moyano, Rubén; Galvez,; Vallejos, Carla; Hernández, Alejandro (1988)Topical application of 0.01 or 0.1% morphine solution to the somatosensory SI area of the rat cerebral cortex significantly decreased the pain intensity rating in the formalin test without producing motor side efects or ...
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Rodríguez De Gracia, Cristina M.; Hernández, Alejandro (2020)El siguiente documento presentará la valoración de Empresa Panameña de Alimentos – EPA-, una empresa dedicada a la producción y comercialización de galletas, caramelos, snacks, cafés, tés, pastas, aceites y margarinas ...