Browsing by Author "Herrera-Marschitz Muller, Mario"
Now showing items 1-16 of 16
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(MDPI, 2022)An animal model of voluntary oral morphine consumption would allow for a pre-clinical evaluation of new treatments aimed at reducing opioid intake in humans. However, the main limitation of oral morphine consumption in ...
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(Frontiers Media S.A., 2017)© 2017 Israel, Karahanian, Ezquer, Morales, Ezquer, Rivera-Meza, Herrera-Marschitz and Quintanilla. This review article addresses the biological factors that influence: (i) the acquisition of alcohol intake; (ii) the ...
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(Frontiers Media, 2021)Background Nicotine is the major addictive component of cigarette smoke and the prime culprit of the failure to quit smoking. Common elements perpetuating the use of addictive drugs are (i) cues associated with the ...
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(Universidad de Chile, 2018)El efecto reforzante del etanol contribuye a la generación de dependencia. Para que el etanol sea reforzante se requiere que este se metabolice a acetaldehído en el cerebro, el cual activa neuronas dopaminérgicas en el ...
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(Blackwell Publishing Ltd, 2018)© 2018 by the Research Society on Alcoholism Background: Life expectancy is greatly reduced in individuals presenting alcohol use disorders and chronic smoking. Literature studies suggest that common mechanisms may apply ...
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(Universidad de Chile, 2012)El presente estudio analiza los cambios en niveles de dopamina (DA) y sus metabolitos medidos de manera cuantitativa con cromatografía líquida de alta performance, in vivo, en neostriado lateral izquierdo y derecho del ...
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(Universidad de Chile, 2007)La dopamina (DA) es el principal neurotransmisor catecolaminérgico del Sistema Nervioso Central (SNC). Esta monoamina es sintetizada, concentrada y liberada mayoritariamente en los ganglios basales. Los ganglios basales ...
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(Universidad de Chile, 2008)Entacapone, inhibidor de la catecol-O-metil-transferasa (COMT), representa una nueva generación de fármacos antiparkinson de los cuales hay escasa información de sus efectos en un modelo clásico para el estudio de ...
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(Universidad de Chile, 2020)The effect of global perinatal asphyxia (PA) on myelination, oligodendrocytes (OLs), neuroinflammation and cell viability was evaluated in telencephalon and hippocampus of rats at postnatal day (P)1, 7 and 14, covering a ...
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(2017)© The Author 2016. Medical Council on Alcohol and Oxford University Press. All rights reserved. Study describes the blockade of relapse-like alcohol drinking by mesenchymal stem cells (MSCs). High alcohol-intake bred rats ...
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(Nature, 2018)Chronic alcohol intake leads to neuroinflammation and astrocyte dysfunction, proposed to perpetuate alcohol consumption and to promote conditioned relapse-like binge drinking. In the present study, human mesenchymal stem ...
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(Universidad de Chile, 2013)Postnatal neurogenesis has been observed in brain regions, such as dentate gyrus of the hippocampus and subventricular zone of telencephalon. Postnatal neurogenesis is an active phenomenon modulated by several factors ...
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(Frontiers Media S.A., 2017)© 2017 Berríos-Cárcamo, Quintanilla, Herrera-Marschitz, Vasiliou, Zapata-Torres and Rivera-Meza. Background: Several studies have shown that the ethanol-derived metabolite salsolinol (SAL) can activate the mesolimbic system, ...
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(Springer New York LLC, 2018)© 2018, Springer Science+Business Media, LLC, part of Springer Nature. The present report evaluates the effect of global perinatal asphyxia on several parameters of oxidative stress and cell viability in rat brain tissue ...
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(Universidad de Chile, 2019)Perinatal asphyxia (PA) is a clinical condition characterized by oxygen deprivation, following PA brain damage progresses, leading to behavioural cognitive disabilities affecting surviving neonates. There is still lack of ...
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(Universidad de Chile, 2021)Perinatal Asphyxia (PA) implies the interruption of oxygen supply, causing energy failure, leading to cell dysfunction and ultimately cell death, affecting in particular neurocircuitries of basal ganglia. The long-term ...
