Browsing by Author "Llanos Vidal, Paola"
Now showing items 1-16 of 16
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(MDPI, 2021)Low-grade chronic inflammation plays a pivotal role in the pathogenesis of insulin resistance (IR), and skeletal muscle has a central role in this condition. NLRP3 inflammasome activation pathways promote low-grade chronic ...
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(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2004-11-26)The syncytiotrophoblast separates the maternal and fetal blood and constitutes the primary barrier for maternal-fetal transport. The Maxi-chloride channel from the apical membrane of the syncytiotrophoblast plays a role ...
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(Universidad de Chile, 2020)El aumento global en la prevalencia de obesidad, insulino-resistencia (IR) y diabetes mellitus tipo 2 (DM2) se ha relacionado con cambios en patrones de estilo de vida y alimentación. Los mecanismos que median estas ...
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(Hindawi, 2021)In men, 70% of circulating testosterone binds with high affinity to plasma sex hormone binding globulin (SHBG), which determines its bioavailability in their target cells. In recent years, a growing body of evidence has ...
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(Universidad de Chile, 2017)INTRODUCCIÓN. La regulación homeostática de los niveles de glucosa en plasma depende de la interacción de distintos órganos de nuestro cuerpo, entre los cuales destaca el músculo esquelético. La captación de glucosa ...
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(Hindawi Publishing Corporation, 2017)© 2017 Maria L. Mizgier et al. Fasting to postprandial transition requires a tight adjustment of insulin secretion to its demand, so tissue (e.g., skeletal muscle) glucose supply is assured while hypo-/hyperglycemia are ...
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(Universidad de Chile, 2017)La comunicación entre los tejidos del sistema musculoesquelético históricamente se ha considerado en base a estímulos mecánicos. Sin embargo, hace una década ha surgido la idea de una comunicación bioquímica entre estos ...
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(Public Library of Science, 2015)© 2015, Public Library of Science. All rights reserved. This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for ...
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(2013)Insulin resistance is defined as a reduced ability of insulin to stimulate glucose utilization. C57BL/6 mice fed with a high-fat diet (HFD) are a model of insulin resistance. In skeletal muscle, hydrogen peroxide (H2O2) ...
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NOX2-Dependent ROS Production is Essential for the Response to Endurance Exercise in Skeletal Muscle (Federation of American Societies for Experimental Biology, 2015)
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(Universidad de Chile, 2017)El transportador ATP Binding Cassette A1 (ABCA1) facilita el flujo de salida de colesterol hacia las apolipoproteinas A-1 (apoA-1) libre de lípidos, siendo una proteína de membrana esencial en las etapas iniciales de la ...
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(Elsevier, 2015)A considerable body of evidence exists implicating high levels of free saturated fatty acids in beta pancreatic cell death, although the molecular mechanisms and the signaling pathways involved have not been clearly ...
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(Public Library of Science, 2017)© 2017 Cataldo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
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(2006)Puroindoline-a (PIN-a) and α1-purothionin (α1-PTH), isolated from wheat endosperm of Triticum aestivum sp., have been suggested to play a role in plant defence mechanisms against phytopathogenic organisms. We investigated ...
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(Universidad de Chile, 2018)La resistencia a la insulina es un estado fisiopatológico altamente prevalente que antecede la aparición de diabetes tipo II. La obesidad como factor predisponente a estas patologías, se asocia a un estado de lipotoxicidad ...
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(American Physiological Society, 2015)Insulin stimulates glucose uptake in adult skeletal muscle by promoting the translocation of GLUT4 glucose transporters to the transverse tubule (T-tubule) membranes, which have particularly high cholesterol levels. We ...
