Browsing by Author "Maass Oñate, Juan"
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Yang, Lu; O’Neill, Paul; Martin, Kareen; Maass Oñate, Juan; Vassilev, Vassil; Ladher, Raj; Groves, Andrew K. (Public Library Science, 2013-01-23)The inner ear develops from a patch of thickened cranial ectoderm adjacent to the hindbrain called the otic placode. Studies in a number of vertebrate species suggest that the initial steps in induction of the otic placode ...
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Maass Oñate, Juan; Gu, Rende; Basch, Martin L.; Waldhaus, Joerg; Martín López, Eduardo; Xia, Anping; Oghalai, John S.; Heller, Stefan; Groves, Andrew K. (NCBI, 2015)Sensorineural hearing loss is most commonly caused by the death of hair cells in the organ of Corti, and once lost, mammalian hair cells do not regenerate. In contrast, other vertebrates such as birds can regenerate hair ...
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Gómez, Andrea V.; Galleguillos, Danny; Maass Oñate, Juan; Battaglioli, Elena; Kukuljan Padilla, Manuel; Andrés, María Estela (CELL PRESS, 2008-07-25)The stress response in cells involves a rapid and transient transcriptional activation of stress genes. It has been shown that Hsp70 limits its own transcriptional activation functioning as a corepressor of heat shock ...
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Zúñiga Pino, Jorge; Maass Oñate, Juan; Arriagada Abarzúa, Christian (2007)Introducción: La angiogénesis es el desarrollo de nuevos vasos sanguíneos desde una red vascular existente, contempla una secuencia de eventos complejos y es fundamental en el proceso reparativo. Existen múltiples factores ...
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Maass Oñate, Juan; Berndt, F. Andrés; Cánovas, José; Kukuljan Padilla, Manuel (Association for Research in Otolaryngology, 2013)The cells in the organ of Corti do not exhibit spontaneous cell regeneration; hair cells that die after damage are not replaced. Supporting cells can be induced to transdifferentiate into hair cells, but that would ...
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Saud, K.; Cánovas, J.; López, C. I.; Berndt, F. A.; López, E.; Maass Oñate, Juan; Barriga, A.; Kukuljan Padilla, Manuel (Elsevier, 2017)The development of the cerebral cortex requires the coordination of multiple processes ranging from the proliferation of progenitors to the migration and establishment of connectivity of the newborn neurons. Epigenetic ...
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Cánovas, José; Berndt, F. Andrés; Sepúlveda, Hugo; Aguilar, Rodrigo; Veloso, Felipe A.; Montecino, Martín; Oliva, Carlos; Maass Oñate, Juan; Sierralta Jara, Jimena; Kukuljan Padilla, Manuel (Soc. Neuroscience, 2015)The acquisition of distinct neuronal fates is fundamental for the function of the cerebral cortex. We find that the development of subcerebral projections from layer 5 neurons in the mouse neocortex depends on the high ...