Browsing by Author "Martínez, Jorge"
Now showing items 1-20 of 24
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(WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-02-15)In this study, we demonstrated that tyrosine phosphorylation of EGFR and the autocrine expression of uPA and HB-EGF depend on the activity of c-jun amino-terminal kinase (JNK) in human prostatic DU-145 cells. These cells ...
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(1998)We investigated the effects of the drug 14-keto-stypodiol diacetate (SDA) extracted from the seaweed product Stypopodium flabelliforme, in inhibiting the cell growth and tumor invasive behavior of DU-145 human prostate ...
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(Wiley-Liss, Inc., 2003-07-04)Mouse-transformed keratinocytes cultured in the presence of transforming growth factor 1 (TGF- 1) acquire an array of morphologic and functional properties that give rise to a migratory phenotype that expresses mesenchymal ...
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(IOP Publishing Ltd, 2018)We report the discovery of distant RR Lyrae stars, including the most distant known in the Milky Way, using data taken in the g-band with the Dark Energy Camera as part of the High cadence Transient Survey (HiTS; 2014 ...
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(Universidad de Chile, 2008)
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(AMER ACAD PERIODONTOLOGY, 2008-04)Background: Platelet-rich plasma is a blood-derived fraction that contains a high concentration of platelets and growth factors. It was proposed that the use of this platelet concentrate stimulates tissue repair. However, ...
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(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004-01-01)Urokinase-type plasminogen activator receptor (uPAR) and epidermal growth factor receptor (EGFR) are ubiquitous receptors involved in the control of a variety of cellular processes frequently found altered in cancer cells. ...
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(Blackwell Munksgaard Ltd, 2004-04-08)Regulation of the extracellular matrix turnover is a crucial process in wound healing and the progress of periodontal disease. It has been proposed that urokinase-type plasminogen activator (uPA), under the control of ...
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(Wiley-Liss, 2001)Bone metastases from prostate origin generate an osteoblastic reaction that is expressed in vitro by increased osteoblast proliferation. The urokinase-like plasminogen activator (u-PA) present in the media conditioned ...
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(MDPI, 2021)Breast tumors belong to the type of desmoplastic lesion in which a stiffer tissue structure is a determinant of breast cancer progression and constitutes a risk factor for breast cancer development. It has been proposed ...
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(Wiley-Liss, 2000)Mesenchymal stem cells (MSCs), precursor cells resident in the bone marrow, have the capacity to differentiate into bone, cartilage, fat, and connective tissue. We have recently reported that MSCs from "healthy" donors ...
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(Universidad de Chile, 2004)
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(Universidad de Chile, 2007)
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(NATURE PUBLISHING GROUP, 2010-09-28)BACKGROUND: The influence of the stromal microenvironment on the progression of epithelial cancers has been demonstrated. Unravelling the mechanisms by which stromal cells affect epithelial behaviour will contribute in ...
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(2010)Obesity-associated health complications are thought to be in part due to the low-grade proinflammatory state that characterizes this disease. The calcium sensing receptor (CaSR), which is expressed in human adipose cells, ...
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(ELSEVIER INC, 2005-09-10)Rho GTPases are overexpressed in human tumors and are involved in a variety of cellular processes such as organization of the actin cytoskeleton, cell-cell contact and malignant transformation. EGFR activation plays a key ...
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(Elsevier Inc., 2008-08-18)modulate the migratory properties in MCF-7 and T47D human mammary cell lines. We also described that the NFjB pathway exerts a downstream control on the expression of the ROS-dependent cellular migratory potential. These ...
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(Universidad de Chile, 2010)El presente estudio, aborda el proceso político vivido en Chile durante el período 1960- 1973, desde del discurso académico-musical de la izquierda. Partiendo de la base de una correlación entre el desarrollo de las ...
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(Springer, 2010)In carcinomas such as those of breast, pancreas, stomach, and colon, cancer cells support the expansion of molecular and cellular stroma in a phenomenon termed desmoplasia, which is characterized by a strong fibrotic response. ...
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(Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies., 2002-04-18)We have examined the effect of transforming growth factor L1 (TGF-L1) and overexpression of the Smad4 gene on the phenotype of Car C, a ras mutated highly malignant spindle carcinoma cell line. TGF-L1-treated Car C cells ...
