Browsing by Author "Melo, Francisco"
Now showing items 1-8 of 8
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Caballero, Leonardo; Mena, Juan; Morales Alvarez, Aurora; Kogan Bocian, Marcelo; Melo, Francisco (Amer Chemical Soc, 2015)We present a method based on atomic force microscopy (AFM) to assess the work of adhesion between the interfaces of gold AFM tips functionalized with three peptides derived from beta-sheet breaker LPFFD [CLPFFD-NH2 (i(0)) ...
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Cornejo, Alberto; Caballero, Julio; Simirgiotis, Mario; Torres, Vanessa; Sánchez, Luisa; Díaz, Nicolás; Guimaraes, Marcela; Hernández, Marcos; Areche Medina, Carlos Alberto; Alfaro, Sergio; Caballero, Leonardo; Melo, Francisco (Taylor & Francis Ltd., 2021)Parkinson’s disease (PD) is a neurodegenerative disorder that affects adult people whose treatment is palliative. Thus, we decided to test three dammarane triterpenes 1, 1a, 1b, and we determined that 1 and 1a inhibit ...
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Espinoza Vergara, Javier; Molina, Paulo; Walter, Mariana; Gulppi, Miguel; Vejar, Nelson; Melo, Francisco; Urzúa Acevedo, Marcela del Pilar; Muñoz, Hugo; Zagal, José H.; Zhou, Xiaorong; Azocar, Manuel I.; Páez, Maritza A. (Frontiers Media, 2021)The influence of pH on the electrochemical behavior of hydrogen peroxide in the presence of Pseudomonas aeruginosa was investigated using electrochemical techniques. Cyclic and square wave voltammetry were used to monitor ...
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Ponce Calderón, Iván Emilio; Garrido, Nelson; Tobar Bachler, Nicolás Andrés; Melo, Francisco; Smith, Patricio; Martínez, Jorge (MDPI, 2021)Breast tumors belong to the type of desmoplastic lesion in which a stiffer tissue structure is a determinant of breast cancer progression and constitutes a risk factor for breast cancer development. It has been proposed ...
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Gordillo Zavaleta, Leonardo José (Universidad de Chile, 2012)Los solitones hidrodinámicos no propagativos son estructuras no lineales localizadas que aparecen en la superficie libre de un líquido cuasi-unidimensional que está sujeto a cierto tipo de inyección de energía, en particular, ...
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Muñoz, Romina; Aguilar Sandoval, Felipe; Wilson Moya, Christian; Melo, Francisco (IOP Publishing, 2015)This paper demonstrates that it is possible to trap and release a super paramagnetic micro bead by fixing three super paramagnetic micro beads in a triangular array at the sensitive end of a micro cantilever, and by simply ...
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Cornejo, Alberto; Aguilar Sandoval, Felipe; Caballero, Leonardo; Machuca, Luis; Muñoz, Patricio; Caballero, Julio; Perry, George; Ardiles, Alejandro; Areche Medina, Carlos; Melo, Francisco (Taylor & Francis, 2017)Alzheimer’s disease is a common tauopathy where fibril formation and aggregates are the hallmark of the disease. Efforts targeting amyloid-b plaques have succeeded to remove plaques but failed in clinical trials to improve ...
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González, Camila; Cartagena, Constanza; Caballero, Leonardo; Melo, Francisco; Areche Medina, Carlos Alberto; Cornejo, Alberto (MDPI, 2021)Neurodegenerative disorders, including Tauopathies that involve tau protein, base their pathological mechanism on forming proteinaceous aggregates, which has a deleterious effect on cells triggering an inflammatory ...