Browsing by Author "Michea Acevedo, Luis"
Now showing items 1-20 of 26
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(Universidad de Chile, 2013)Niveles elevados de aldosterona causan hipertensión arterial y un estado inflamatorio moderado en tejido renal y cardiovascular. La evidencia clínica y experimental ha demostrado que el bloqueo del receptor de aldoste ...
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(American Association of Immunologists, 2010)Excessive production of aldosterone leads to the development of hypertension and cardiovascular disease by generating an inflammatory state that can be promoted by T cell immunity. Because nature and intensity of T cell ...
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(2012)Background: Hemodialysis patients (HD) display high rates of cardiac disease and mortality. The cardiovascular morbidity and mortality of HD patients is attributable in a signifi cant proportion to endothelial dysfunction, ...
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(Universidad de Chile, 2018)La anemia en la enfermedad renal crónica (ERC) es frecuente y se asocia a mayor morbimortalidad y mala calidad de vida. En la etiopatogenia de la anemia de la ERC destaca la resistencia a la acción de la hormona eritropoyetina ...
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(1995)In this study, we tested the adhesion-promoting role of major intrinsic protein from both normal human (cadaver) and senile cataractous lenses. Junctional membrane solubilized proteins and pure major intrinsic protein ...
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(Universidad de Chile, 2019-07)Aumentos de Angiotensina II (AngII) plasmática causan Hipertensión Arterial (HTA), inflamación y daño de tejidos blanco. Estudios recientes indican que el sistema inmune participa en la generación del aumento de presión ...
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(Elsevier Inc., 2009)E Prostanoid (EP) receptors play an important role in urinary Na+ excretion. In the kidney, the epithelial sodium channel (ENaC) is the rate-limiting-step for Na+ reabsorption. We hypothesized that activation of EP1/EP3 ...
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(American Heart Association, 2009)Recent studies have shown that the epithelial sodium channel (ENaC) is expressed in vascular tissue. However, the role that ENaC may play in the responses to vasoconstrictors and NO production has yet to be addressed. In ...
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(WILEY-BLACKWELL, 2011-09)Nitric oxide (NO) has been proposed to down-regulate NMDA receptors (NMDA-Rs) in a homeostatic manner. However, NMDA-R-dependent NO synthesis also can cause excitotoxic cell death. Using bicuculline-stimulated hippocampal ...
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(Society of Biology of Chile, 2012)Th17 cells, a recently described subtype of CD4+ effector lymphocytes, have been linked to cell-mediated autoimmune and inflammatory diseases as well as to cardiovascular diseases. However, the participation of IL-17A in ...
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(Hospital Clínico Universidad de Chile, 2010)Klotho, a recently described gene, is mainly expressed in the kidney, and encodes a proteinnecessary for the activity of fibroblast growth factor receptors (FGFR), especially FGFR1. TheKlotho protein has two variants, a ...
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(2012)Objective To determine whether maternal plasma levels of 2-methoxyestradiol (2-ME) are decreased early in pregnancies that subsequently develop pre-eclampsia (PE) and whether this difference could be attributed to ...
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(Universidad de Chile, 2015)La Injuria Renal Aguda (AKI) es una patología de alta morbimortalidad, con prevalencia mayor al 40% en pacientes críticos, especialmente en aquellos con sepsis. El diagnóstico tardío es uno de los factores que determinan ...
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(LIPPINCOTT WILLIAMS & WILKINS, 2008-08)Chronic renal failure causes left ventricular hypertrophy, but the molecular mechanisms involved remain unknown. We, therefore, investigated whether the mineralocorticoid receptor is implicated in the cardiac hypertrophy ...
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(Taylor & Francis, 2017)Renal sodium reabsorption depends on the activity of the Na+,K+-ATPase / heterodimer. Four ((1-4)) and 3 ((1-3)) subunit isoforms have been described. It is accepted that renal tubule cells express (1)/(1) dimers. Aldosterone ...
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(Lippincott Williams & Wilkins, 2018)Increasing evidence shows that antigen-presenting cells (APCs) are involved in the development of inflammation associated to hypertension. However, the potential role of APCs in the modulation of renal sodium transport has ...
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(Niels Olsen Saraiva Caˆmara, Universidade de Sao Paulo, Brazil, 2012)The current hypothesis postulates that NFAT5 activation in the kidney’s inner medulla is due to hypertonicity, resulting in cell protection. Additionally, the renal medulla is hypoxic (10–18 mmHg); however there is no ...
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(Universidad de Chile, 2019)La enfermedad renal crónica (ERC) es la pérdida progresiva de la función renal durante un periodo que va desde meses a años. En estados avanzados, la ERC se presenta con complicaciones como enfermedades cardiovasculares, ...
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(Universidad de Chile, 2007)La calcificación arterial es un importante factor de riesgo asociado a morbilidad y mortalidad cardiovascular. La arterioesclerosis o esclerosis de Mönckeberg es un tipo de calcificación que involucra específicamente a ...
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(Portland Press Ltd, 2014)Chronic RAS (renin-angiotensin system) activation by both AngII (angiotensin II) and aldosterone leads to hypertension and perpetuates a cascade of pro-hypertrophic, pro-inflammatory, pro-thrombotic and atherogenic effects ...
