Browsing by Author "Núñez González, Marco"
Now showing items 1-20 of 39
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(Soc Neuroscience, 2016)Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca2+, a broad intracellular second messenger, promotes both Rac1 ...
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(AMER SOC NUTRITION, 2012-03)Ferritin iron from food is readily bioavailable to humans and has the potential for treating iron deficiency. Whether ferritin iron absorption is mechanistically different from iron absorption from small iron complexes/salts ...
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(Springer-Verlag, 1989)A59Fe assay was designed to detect an Fe(III) binding capacity in NP-40 solubilized proteins from rabbit reticulocyte endocytic vesicles. The iron binding capacity had an apparent molecular weight as determined by gel ...
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(Wiley-VCH Verlag, 2018)© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Lipid droplets (LDs) have been recognized as highly dynamic cellular organelles involved in important biological functions for the survival of organisms such as supplying ...
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(Journal of Nutrition, 2008-05)Iron deficiency, a condition currently affecting ;3 billion people, persists in the 21st century despite half a millennium of medical treatment. Soybean ferritin (SBFn), a large, stable protein nanocage around a mineral ...
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(Company of Biologists Ltd., 2015)Reactive oxygen species (ROS) produced by the NADPH oxidase (NOX) complex play important physiological and pathological roles in neurotransmission and neurodegeneration, respectively. However, the contribution of ROS to ...
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(MDPI, 2014)Two new coumarin-based “turn-off” fluorescent probes, (E)-3-((3,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS1) and (E)-3-((2,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS2), were synthesized ...
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(Elsevier, 2014)In this Letter we present a new probe, (E)-7-(diethylamino)-2-oxo-2H-chromene-3-carbaldehyde oxime (JB), which can detect Cu2+ ions in HEPES buffer under physiological conditions. Benesi–Hildebrand and Job plots demonstrate ...
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(Elsevier Masson SAS, 2013)A new coumarin-based 'turn-off' fluorescent probe, 7-(diethylamino)-N-(1,3- dihydroxy-2-(hydroxymethyl) propan-2-yl)-2-oxo-2H-chromene-3-carboxamide (AGD) was synthesized. This compound is highly selective for ferrous ions ...
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(2013)A new coumarin-based ‘turn-off’ fluorescent probe, 7-(diethylamino)-N-(1,3-dihydroxy-2-(hydroxymethyl) propan-2-yl)-2-oxo-2H-chromene-3-carboxamide (AGD) was synthesized. This compound is highly selective for ferrous ...
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(NATL ACAD SCIENCES, 2008-11-25)Dopaminergic cell death in the substantia nigra (SN) is central to Parkinson’s disease (PD), but the neurodegenerative mechanisms have not been completely elucidated. Iron accumulation in dopaminergic and glial cells ...
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(2008)Dopaminergic cell death in the substantia nigra (SN) is central to Parkinson's disease (PD), but the neurodegenerative mechanisms have not been completely elucidated. Iron accumulation in dopaminergic and glial cells in ...
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(Universidad de Chile, 2023)El hierro y el calcio son micronutrientes esenciales para el crecimiento y normal desarrollo de los seres humanos. El hierro es un componente esencial para el desarrollo de los procesos celulares, debido a su capacidad de ...
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(American Physiological Society, 2013)Ferritin, a food constituent of animal and vegetal origin, is a source of dietary iron. Its hollow central cavity has the capacity to store up to 4,500 atoms of iron, so its potential as an iron donor is advantageous to ...
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(Universidad de Chile, 2010)Debido a su capacidad de formar complejos de coordinación con ligandos orgánicos, el hierro participa ei1 procesos celulares básicos como fosforilación oxidativa, transporte y almacenamiento de oxígeno, metabolismo de ...
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(2013)Inflammation and iron accumulation are present in a variety of neurodegenerative diseases that include Alzheimer’s disease and Parkinson’s disease. The study of the putative association between inflammation and iron ...
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(2006)Interactions of micronutrients can affect absorption and bioavailability of other nutrients by a number of mechanisms. In aqueous solutions, and at higher uptake levels, competition between elements with similar chemical ...
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(SOCIEDAD BIOLGIA CHILE, 2005-05-05)Interactions of micronutrients can affect absorption and bioavailability of other nutrients by a number of mechanisms. In aqueous solutions, and at higher uptake levels, competition between elements with similar chemical ...
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(Frontiers Research Foundation, 2014)A growing set of observations points to mitochondrial dysfunction, iron accumulation, oxidative damage and chronic inflammation as common pathognomonic signs of a number of neurodegenerative diseases that includes Alzheimer's ...
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(2006)Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In particular, there is increasing evidence that iron progressively accumulates in the brain with age and that ...
