Browsing by Author "Orio, Patricio"

Now showing items 1-4 of 4

    • Acute activation of Maxi-K channels (hSlo) by estradiol binding to the beta subunit 
      Valverde, Miguel A.; Rojas, Patricio; Amigo, Julio; Cosmelli, Diego; Orio, Patricio; Bahamonde Miranda, María Inés; Mann, Giovanni E.; Vergara Montecinos, Cecilia; Latorre, Ramón (AMER ASSOC ADVANCEMENT SCIENCE, 1999-09-17)
      Maxi-K channels consist of a pore-forming alpha subunit and a regulatory beta subunit, which confers the channel with a higher Ca2+ sensitivity. Estradiol bound to the beta subunit and activated the Maxi-K channel (hSlo) ...
    • Apical sorting of a voltage- and Ca2+-activated K+ channel alpha-subunit in Madin-Darby canine kidney cells ... 
      Bravo Zehnder, Marcela; Orio, Patricio; Norambuena, Andrés; Wallner, Martín; Meera, Pratap; Toro, Ligia; Latorre, Ramón; González, Alfonso (NATL ACAD SCIENCES, 2000-11-21)
      The voltage- and Ca2+-acttiated K+ (K-V,K-Ca) channel is expressed in a variety of polarized epithelial cells seemingly displaying a tissue-dependent apical-to-basolateral regionalization, as revealed by electrophysiology. ...
    • Differential effects of beta 1 and beta 2 subunits on BK channel activity 
      Orio, Patricio; Latorre, Ramón (ROCKEFELLER UNIV PRESS, 2005-04)
      High conductance, calcium- and voltage-activated potassium (BK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory (beta) ...
    • Structural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated ... 
      Orio, Patricio; Torres, Yolima; Rojas, Patricio; Carvacho, Ingrid; García, María L.; Toro, Ligia; Valverde, Miguel A.; Latorre, Ramón (ROCKEFELLER UNIV PRESS, 2006-02)
      High conductance, calcium- and voltage-activated potassium (BK, MaxiK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory ...