Browsing by Author "Palma Alvarado, Verónica"
Now showing items 1-14 of 14
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(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2006-07)The combination of accessible embryology and forward genetic techniques has made zebrafish a powerful model system for the study of vertebrate development. One limitation of genetic analysis is that the study of gene ...
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(Universidad de Chile, 2017)En el cáncer, la compleja relación espacio-temporal entre las células tumorales y su microambiente es determinante en el crecimiento, invasión y capacidad de metástasis de los tumores. Es por eso que el estudio de esta ...
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(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2007-12-11)The Hedgehog (Hh) signaling pathway plays critical instructional roles during embryonic development. Misregulation of Hh/Gli signaling is a major causative factor in human congenital disorders and in a variety of cancers. ...
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(Universidad de Chile, 2023)El glioblastoma es el tumor cerebral más agresivo, invasivo e indiferenciado entre los gliomas, designado grado IV por la OMS. Hasta la fecha, no se han desarrollado terapias efectivas para su erradicación, por lo que el ...
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(Universidad de Chile, 2017)Anualmente se producen cerca de 9 millones de fracturas por fragilidad ósea en el mundo. El hueso es el segundo tejido con mayor demanda de trasplantes en el sistema de salud, en donde se emplean injertos autógenos y ...
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(WILEY-BLACKWELL, 2016)Birds have a distally reduced, splinter-like fibula that is shorter than the tibia. In embryonic development, both skeletal elements start out with similar lengths. We examined molecular markers of cartilage differentiation ...
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Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression (UICC, 2014)The canonical Sonic Hedgehog (Shh)/Gli pathway plays multiples roles during central nervous system (CNS) development. To elucidate the molecular repertoire of Shh mediators, we have recently described novel transcriptional ...
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(Universidad de Chile, 2011)El mitógeno Sonic hedgehog (Shh) participa en el desarrollo del Sistema nervioso Central (SNC), jugando un rol clave en ia proliferación de progenitores neurales, entre otros. C-myc es un potente proto-oncogen y regulador ...
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(Universidad de Chile, 2010)
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(Frontiers Research Foundation, 2015)The subventricular zone (SVZ) is one of the main niches of neural stem cells in the adult mammalian brain. Stem and precursor cells in this region are the source for neurogenesis and oligodendrogesis, mainly in the olfactory ...
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(PLoS ONE, 2013)The Sonic Hedgehog (Shh) pathway is responsible for critical patterning events early in development and for regulating the delicate balance between proliferation and differentiation in the developing and adult vertebrate ...
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(SOC BIOLGIA CHILE, 2011)Proliferation and cell fate determination in the developing embryo are extrinsically regulated by multiple interactions among diverse secreted factors, such as Sonic Hedgehog (SHh), which act in a concentration-dependent ...
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(SAGE PUBLICATIONS INC, 2011-04)Regulation of cell renewal in the periodontium is a critical cell function that has not been clarified. Sonic hedgehog (Shh) is a secreted signaling molecule that plays a key role during development and adult tissue ...
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(BIOMED CENTRAL LTD, 2012-01-03)Background: The increasing number of developmental events and molecular mechanisms associated with the Hedgehog (Hh) pathway from Drosophila to vertebrates, suggest that gene regulation is crucial for diverse cellular ...
