Browsing by Author "Quest, Andrew F. G."
Now showing items 1-20 of 73
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(Landes Bioscience, 2014)© Jorge Díaz, Pablo endoza, Patricio Silva, Andrew FG Quest, and Vicente A Torres. The small GTPase Rab5 has been frequently studied in the context of intracellular trafficking, but evidence obtained more recently has ...
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(2011)Unlike apoptosis, mechanisms leading to necrosis are less well understood. Moreover, changes in necrosis as a function of age have not been studied in human lymphocytes. H 2O 2-induced death of peripheral lymphocytes (56 ...
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(Universidad de Chile, 2017)Los exosomas son vesículas extracelulares de tamaño nanométrico involucradas en la comunicación celular. El desarrollo de “nanovehículos”, como los exosomas, es una innovadora estrategia para optimizar la entrega de fármacos ...
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(Universidad de Chile, 2018)La periodontitis es una enfermedad inflamatoria crónica de las estructuras que soportan las piezas dentales, la cual está asociada a un proceso infeccioso causado por un cambio en la ecología local de la biopelícula ...
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(Academic Press Inc., 2018)© 2018 Elsevier Inc.Here, we determined the 5-hydroxymethylcytosine (5hmC), 5-methylcytosine (5mC), Ten Eleven Translocation (TETs), and DNA methyltransferases (DNMTs) levels in epithelial and inflammatory cells of labial ...
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(Elsevier B.V., 2017)© 2016 Elsevier B.V. Two key proteins for cellular communication between astrocytes and neurons are αvβ3 integrin and the receptor Thy-1. Binding of these molecules in the same (cis) or on adjacent (trans) cellular membranes ...
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(2012)Thy-1 is a membrane glycoprotein suggested to stabilize or inhibit growth of neuronal processes. However, its precise function has remained obscure, because its endogenous ligand is unknown. We previously showed that Thy-1 ...
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(2011)Thy-1, an abundant mammalian glycoprotein, interacts with avβ3 integrin and syndecan-4 in astrocytes and thus triggers signaling events that involve RhoA and its effector p160ROCK, thereby increasing astrocyte adhesion to ...
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(Elsevier Inc., 2018)© 2018 Elsevier Inc. Non-communicable diseases (NCDs), also known as chronic diseases, are long-lasting conditions that affect millions of people around the world. Different factors contribute to their genesis and progression; ...
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(2006)Increased expression of casein kinase 2 (CK2) is associated with hyperproliferation and suppression of apoptosis in cancer. Mutations in the tumor suppressor APC (adenomatous polyposis coli) are frequent in colon cancer ...
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(Society of Biology of Chile, 2002)Caveolae are small, flask-shaped invaginations of the plasma membrane present on a large number of mammalian cells. Recent results obtained with knock-out mice for the gene caveolin-1 demonstrate that expression of caveolin-1 ...
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(Future Medicine Ltd., 2018)© 2018 2018 Future Medicine Ltd. Breast cancer is one of the most frequently diagnosed cancers and the leading cause of cancer-related deaths in women worldwide, whereby mortality is largely attributable to the development ...
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(2002)Reactive oxygen species are now widely recognized as important players contributing both to cell homeostasis and the development of disease. In this respect nitric oxide (NO) is no exception. The discussion here will center ...
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(2008)Caveolae are small plasma membrane invaginations that have been implicated in a variety of functions including transcytosis, potocytosis and cholesterol transport and signal transduction. The major protein component of ...
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(Universidad de Chile, 2015)El cáncer constituye una de las principales causas de muerte en Chile y el mundo. Particularmente, la agresividad de esta enfermedad subyace en la diseminación de las células tumorales hacia otros tejidos, fenómeno ...
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(Universidad de Chile, 2009)
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(Universidad de Chile, 2013)El cáncer es la 2° causa de muerte en Chile. El desarrollo del cáncer se ha propuesto que es consecuencia de la pérdida de función de los genes supresores de tumores beneficiando la acción de los oncogenes (genes que ...
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(Society of Biology of Chile, 2002)Cellular signaling is an area of intense research that transcends all fields of experimental biology. As such, progress in this domain will continue to have an ever-increasing impact on society in general and health-related ...
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(2011)Objective Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
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(Universidad de Chile, 2003)La proteínaquinasa CK1 es una enzima altamente ubícua y conservada en todos los eucariontes estudiados y, particularmente, dentro de los vertebrados. En estos organismos, la enzima existe como una familia de siete miembros ...
