Browsing by Author "Ramírez Sagredo, Andrea Soledad"

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    • Policistina-1 regula mitofagia en cardiomiocitos en un mecanismo dependiente de FoxO1 
      Ramírez Sagredo, Andrea Soledad (Universidad de Chile, 2021)
      Antecedentes: La enfermedad renal poliquística autosomal dominante (ADPKD) es una patología derivada de la mutación del gen pdk1 de la policistina-1 (PC1). Los pacientes con ADPKD presentan alteraciones metabólicas a ...
    • Polycystin-1 regulates cardiomyocyte mitophagy 
      Ramírez Sagredo, Andrea Soledad; Quiroga, Clara; Garrido Moreno, Valeria Soraya; López Crisosto, Camila; Leiva Navarrete, Sebastián Rolando; Norambuena Soto, Ignacio Estebán; Ortiz Quintero, Jose Jafet; Díaz Vesga, Magda C.; Pérez, William; Hendrickson, Troy; Parra Ortiz, Valentina Maria; Pedrozo Cibils, Zully Rocio Evangelina; Altamirano, Francisco; Chiong Lay, Mario Martin; Lavandero Gonzalez, Sergio Alejandro (Wiley, 2021)
      Polycystin-1 (PC1) is a transmembrane protein found in different cell types, including cardiomyocytes. Alterations in PC1 expression have been linked to mitochondrial damage in renal tubule cells and in patients with ...