Browsing by Author "Sáez Briones, Patricio"

Now showing items 1-9 of 9

    • Aromatic Bromination Abolishes the Psychomotor Features and Pro-social Responses of MDMA (“Ecstasy”) in ... 
      Sáez Briones, Patricio; Castro Castillo, Vicente; Díaz Véliz, Gabriela; Valladares Boasi, Luis; Barra, Rafael; Hernández, Alejandro; Cassels Niven, Bruce (Frontiers Media S.A., 2019)
      The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin. ...
    • Behavioral Profiles in Rats Distinguish Among "Ecstasy," Methamphetamine and 2,5-Dimethoxy-4-Iodoamphetamine: ... 
      Quinteros Muñoz, David; Sáez Briones, Patricio; Díaz Véliz, Emma; Mora Gutiérrez, Sergio; Rebolledo Fuentes, Marco; Cassels Niven, Bruce (AMER PSYCHOLOGICAL ASSOC, 2010-06-30)
      3,4-methylenedioxymethamphetamine (MDMA; “ecstasy”) is a psychoactive drug structurally related to other phenylisopropylamines acting as stimulants or hallucinogens in humans. Although MDMA has a pharmacological identity ...
    • beta(2)-Adrenoceptor stimulation restores frontal cortex plasticity and improves visuospatial performance ... 
      Sáez Briones, Patricio; Soto Moyano, Rubén; Burgos, Héctor; Castillo, Amparo; Valladares Boasi, Luis; Morgan Sabat, Carlos; Pérez, Hernán; Barra, Rafael; Constandil, Luis; Laurido, Claudio; Hernández, Alejandro (Elsevier, 2015)
      Moderate reduction in dietary protein composition of pregnant rats from 25% to 8% casein, calorically compensated by carbohydrates, has been described as a ‘‘hidden malnutrition’’ because it does not alter body and brain ...
    • Dark Classics in Chemical Neuroscience: Mescaline 
      Cassels Niven, Bruce; Sáez Briones, Patricio (American Chemical Society, 2018)
      Archeological studies in the United States, Mexico, and Peru suggest that mescaline, as a cactus constituent, has been used for more than 6000 years. Although it is a widespread cactus alkaloid, it is present in high ...
    • Facts and hypotheses about the programming of neuroplastic deficits by prenatal malnutrition 
      Barra, Rafael; Morgan, Carlos; Sáez Briones, Patricio; Reyes Parada, Miguel; Burgos, Héctor; Morales, Bernardo; Hernández, Alejandro (Oxford University Press, 2019)
      © The Author(s) 2018.Studies in rats have shown that a decrease in either protein content or total dietary calories results in molecular, structural, and functional changes in the cerebral cortex and hippocampus, among ...
    • Hypertension in prenatally undernourished young-adult rats is maintained by tonic reciprocal paraventricu ... 
      Cayupe, Bernardita; Morgan, Carlos; Puentes, Gustavo; Valladares Boasi, Luis Emilio; Burgos, Héctor; Castillo, Amparo; Hernández, Alejandro; Constandil, Luis; Ríos, Miguel; Sáez Briones, Patricio; Barra, Rafael (MDPI, 2021)
      Prenatally malnourished rats develop hypertension in adulthood, in part through increased alpha(1)-adrenoceptor-mediated outflow from the paraventricular nucleus (PVN) to the sympathetic system. We studied whether both ...
    • Influence of protonation on substrate and inhibitor interactions at the active site of human monoamine oxidase-A 
      Zapata Torres, Gerald; Fierro, Angelica; Miranda Rojas, Sebastián; Guajardo, Carlos; Sáez Briones, Patricio; Salgado, J. Cristian; Celis Barros, Cristian (2012)
      Although substrate conversion mediated by human monoaminooxidase (hMAO) has been associated with the deprotonated state of their amine moiety, data regarding the influence of protonation on substrate binding at the active ...
    • Preference for high-fat diet is developed by young Swiss CD1 mice after short-term feeding and is prevented ... 
      Buttigieg, Angie; Flores, Osvaldo; Hernández, Alejandro; Sáez Briones, Patricio; Burgos, Héctor; Morgan Sabat, Carlos (Elsevier, 2014)
      Obesity is a worldwide epidemic that is increasing at an alarming rate. One of its causes is the increased availability and consumption of diets rich in fat. In the present study, we investigated the effects of ...
    • β2-Adrenoceptor stimulation restores frontal cortex plasticity and improves visuospatial performance in ... 
      Sáez Briones, Patricio; Soto Moyano, Rubén; Burgos, Héctor; Castillo, Amparo; Valladares Boasi, Luis; Morgan, Carlos; Pérez, Hernán; Barra, Rafael; Constandil, Luis; Laurido, Claudio; Hernández, Alejandro (Academic Press Inc., 2015)
      © 2014 Elsevier Inc.Moderate reduction in dietary protein composition of pregnant rats from 25% to 8% casein, calorically compensated by carbohydrates, has been described as a "hidden malnutrition" because it does not alter ...