Now showing items 1-20 of 27

    • Maza León, Verónica de la; Simian, Daniela; Castro, Magdalena; Torres, Juan Pablo; Lucero, Yudeth; Sepúlveda, Fanny; Mazquiaran, Soraya; Salazar, Carolina; Segovia, Lorena; Santolaya de Pablo, María Elena (Lippicott Williams & Wilkins, 2015)
      Background: Early administration of antimicrobial (AM) is relevant in children with cancer, fever and neutropenia (FN). The recommendation is to administer the first dose of AM within the first hour of hospital admission. ...
    • Solís, Yanahara; Álvarez, Ana M.; Fuentes, David; de la Barra, Daniela; Avilés, Carmen L.; Becker, Ana; Salgado, Carmen; Silva, Pamela; Topelberg, Santiago; Tordecilla, Juan; Varas, Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela; Aedo Monsalve, Sócrates; Santolaya de Pablo, María Elena (2012)
      Introduction: To determine the etiology of invasive bacterial infection in high risk febrile neutropenia (HRFN) episodes in children with cancer is essential because of the favorable impact on mortality of the early empiric ...
    • Izquierdo Copiz, Giannina; Santolaya de Pablo, María Elena (Sociedad Chilena de Infectología, 2014)
      Invasive fungal infections have become an increasingly common problem in neonatal intensive care units (NICU). Invasive candidiasis (IC) is associated with substantial morbidity and mortality rates, especially in ...
    • Ducasse, Karen; Fernández, José P.; Salgado Muñoz, Carmen; Álvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; Topelberg, Santiago; Tordecilla Cadiu, Juan; Varas P., Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela; Santolaya de Pablo, María Elena (Sociedad Chilena de Infectología, 2014)
      Leukemia is the most common cancer in Chilean children. Acute lymphoblastic leukemia (ALL) is more prevalent and longer survival compared to acute myeloid leukemia (AML). Aims: To describe episodes of febrile neutropenia ...
    • Farfán, Mauricio J.; Torres Torretti, Juan Pablo; Vergara A., Alejandra; Donoso W., Gloria; Alba G., Andrea; Paris D., Claudia; Santolaya de Pablo, María Elena (SOC CHILENA INFECTOLOGIA, 2011-04)
      Background: Cytomegal virus (CMV) infections are an important cause of morbidity and mortality in transplant recipient. To date, the antigenemia assay is the most used technique for diagnostic and management of CMV ...
    • Rüttimann, Ricardo Walter; Gentile, Ángela; Macías Parra, Mercedes; Sáez Llorens, Xavier; Palazzi Safadi, Marco Aurelio; Santolaya de Pablo, María Elena (Lippincott Williams & Wilkins, 2014)
      Invasive meningococcal disease is a serious infection that occurs worldwide. Neisseria meningitidis remains one of the leading causes of bacterial meningitis in all ages. Despite the availability of safe and effective vaccines ...
    • Paris, Claudia; Kopp, Katherine; King, Alejandra; Santolaya de Pablo, María Elena; Zepeda, Ana J.; Palma, Julia (2009)
      Background. Cytomegalovirus (CMV) infection remains as an important cause of morbidity and mortality in children undergoing hematopoietic stem cell transplantation (HSCT). Our aim was to assess the incidence, risk factors, ...
    • Santolaya de Pablo, María Elena; Alvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; Cofré, José; Cumsille Garib, Miguel; O'Ryan Gallardo, Miguel; Payá, Ernesto; Salgado, Carmen; Silva, Pamela; Tordecilla, Juan; Varas P., Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela (2004-09-15)
      Purpose To compare outcome and cost of ambulatory versus hospitalized management among febrile neutropenic children at low risk for invasive bacterial infection (IBI). Patients and Methods Children presenting with ...
    • Nucci, Marcio; Queiroz Telles, Flavio; Alvarado Matute, Tito; Tiraboschi, Iris Nora; Cortés, Jorge; Zurita, Jeannete; Guzmán Blanco, Manuel; Santolaya de Pablo, María Elena; Thompson, Luis; Sifuentes Osornio, José; Echevarría, Juan I.; Colombo, Arnaldo L. (Plos One, 2013-03)
      Background: The epidemiology of candidemia varies depending on the geographic region. Little is known about the epidemiology of candidemia in Latin America. Methods: We conducted a 24-month laboratory-based survey of ...
    • Zúñiga Contreras, Marcela Alejandra; Hauck, Isabel Noemí; Valenzuela Cortés, Romina; Barraza Olivares, Marlon; Santolaya de Pablo, María Elena (Sociedad Chilena de Infectología, 2021)
      Toxoplasma gondii es un protozoo que afecta a un tercio de la población mundial y cuya seroprevalencia actualizada en niños con cáncer en nuestro medio, se desconoce. Objetivo: Describir la seroprevalencia de IgG anti-T. ...
    • Torres, Juan P.; Labraña, Yenis; Ibañez, Carolina; Kasaneva, Pilar; Farfán, Mauricio J.; Maza León, Verónica de la; Villarroel, Milena; Vergara, Ivonne; Piemonte, Paula; Zubieta, Marcela; Salgado, Carmen; Tordecilla, Juan; Topelberg, Santiago; O'Ryan Gallardo, Miguel; Santolaya de Pablo, María Elena (Lippincott Williams and Wilkins, 2012)
      Background: The role of respiratory viral infections (RVIs) as a cause of overall fever and neutropenia (FN) episodes in children with cancer has been less characterized than bacterial infections. We conducted a study aimed ...
    • Abad, Raquel; Martinón-Torres, Federico; Santolaya de Pablo, María Elena; Banzhoff, Angelika; González-Inchausti, Carmen; Graña, Maria Gabriela; Vázquez, Julio A. (Sociedad Espanola de Quiminoterapia, 2019)
      © 2019, Sociedad Espanola de Quiminoterapia. All rights reserved.Invasive meningococcal disease (IMD), caused by the bacterium Neisseria meningitidis, entails significant mortality and morbidity. Disease incidence is highest ...
    • Lehrnbecher, Thomas; Phillips, Robert; Alexander, Sarah; Alvaro, Frank; Carlesse, Fabianne; Fisher, Brian; Hakim, Hana; Santolaya de Pablo, María Elena; Castagnola, Elio; Davis, Bonnie L.; Lee Dupuis, L.; Gibson, Faith; Groll, Andreas H.; Gaur, Aditya; Gupta, Ajay; Kebudi, Rejin; Petri (American Society of Clinical Oncology, 2012)
      Purpose: To develop an evidence-based guideline for the empiric management of pediatric fever and neutropenia (FN). Methods: The International Pediatric Fever and Neutropenia Guideline Panel is a multidisciplinary and ...
    • Santolaya de Pablo, María Elena; O'Ryan Gallardo, Miguel; Valenzuela Bravo, María Teresa; Prado Jiménez, Valeria; Vergara, Rodrigo C.; Muñoz, Alma; Toneatto, Daniela; Graña, Gabriela; Wang, Huajun; Clemens, Ralf; Dull, Peter M. (Elsevier, 2012-02-18)
      Background Effective glycoconjugate vaccines against Neisseria meningitidis serogroups A, C, W-135, and Y have been developed, but serogroup B remains a major cause of severe invasive disease in infants and adolescents ...
    • Rivacoba Rojas, María Carolina; Cofré Guerra, José; Santolaya de Pablo, María Elena (Sociedad Chilena de Infectología, 2016)
      Invasive pneumococcal disease (IPD) remains as an important cause of morbidity in the world and in our country, while in Chile the incidence has decreased after the incorporation of the 10 valent pneumococcal conjugate vaccine, ...
    • Conca Minaeff, Natalia; Yenis Labraña, C.; Bercovich W., Mariana; Cienfuegos, Guillermo; Santolaya de Pablo, María Elena (2011)
      Herpes simplex encephalitis is an infrequent infection with high mortality and morbidity. Antiviral therapies decrease mortality but long term sequelae are still high, so early diagnosis is important for opportune treatment. ...
    • Santolaya de Pablo, María Elena; Alvarez, Ana M.; Aviles, Carmen L.; Becker, Ana; King, Alejandra; Mosso, Claudio; O'Ryan Gallardo, Miguel; Paya, Ernesto; Salgado, Carmen; Silva, Pamela; Topelberg, Santiago; Tordecilla, Juan; Varas, Monica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marc (Lippincott Williams and Wilkins, 2008)
      Background: Severe sepsis is not clinically apparent during the first 24 hours of hospitalization in most children with cancer and febrile neutropenia (FN), delaying targeted interventions that could impact mortality. The ...
    • Farfán Urzúa, Mauricio Javier; Salas, Carolina; Canales López, Cristina; Silva, Felipe; Villarroel, Milena; Kopp, Katherine; Torres Torretti, Juan Pablo; Santolaya de Pablo, María Elena; Morales, Jorge (BioMed Central, 2014)
      Background: Mercaptopurine (6-MP) plays a pivotal role in treatment of childhood acute lymphoblastic leukemia (ALL); however, interindividual variability in toxicity of this drug due to genetic polymorphism in 6-MP ...
    • Santolaya de Pablo, María Elena; Alvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; Cofré, José; Enríquez, N.; O'Ryan Gallardo, Miguel; Payá, Ernesto; Salgado, Carmen; Silva, Pamela; Tordecilla, Juan; Varas P., Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela (2002)
      A risk prediction model for invasive bacterial infection (IBI) was prospectively evaluated among children presenting with cancer, fever, and neutropenia. The model incorporated assessment of 5 previously identified risk ...
    • Santolaya de Pablo, María Elena; Alvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; Venegas, Marcela; O'Ryan Gallardo, Miguel; Salgado, Carmen; Topelberg, Santiago; Tordecilla, Juan; Varas, Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela; Maza León, Verónica de la; Vergara, Alejandra; Farfán, Mauricio J.; Torres Torretti, Juan Pablo (Lippincott Williams & Wilkins, 2013)
      Background: We previously created a risk prediction model for severe sepsis not clinically apparent during the first 24 hours of hospitalization in children with high-risk febrile neutropenia (HRFN), which identified 3 ...