Browsing by Author "Sepúlveda Rivas, Sabrina"
Now showing items 1-4 of 4
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Sepúlveda Rivas, Sabrina; Fritz, Hans F.; Valenzuela, Camila; Santiviago, Carlos A.; Morales, Javier O. (MDPI AG, 2019)The number of biologic drugs has increased in the pharmaceutical industry due to their high therapeutic efficacy and selectivity. As such, safe and biocompatible delivery systems to improve their stability and efficacy are ...
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Sepúlveda Rivas, Sabrina; Leal, Matías S.; Pedrozo Cibils, Zully Rocío Evangelina; Kogan, Marcelo Javier; Ocaranza Jeraldino, María Paz Alejandra; Morales Montecinos, Javier Octavio (MDPI, 2021)Ang-(1-9) peptide is a bioactive vasodilator peptide that prevents cardiomyocyte hypertrophy in vitro and in vivo as well as lowers blood pressure and pathological cardiovascular remodeling; however, it has a reduced ...
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Sepúlveda Rivas, Sabrina (Universidad de Chile, 2019)En esta tesis se formularon y desarrollaron nanopartículas poliméricas que fueron cargadas con el péptido angiotensina Ang-(1-9) y nanoesferas de oro. Ang-(1-9) corresponde a un péptido vasodilatador el cual contrarresta ...
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Morales Montecinos, Javier; Sepúlveda Rivas, Sabrina; Oyarzún Ampuero, Felipe; Lavandero González, Sergio; Kogan Bocian, Marcelo (Bentham, 2015)Applications of polymeric nanotechnologies for enabling therapies for cardiovascular diseases have shown recent success. Both intravenous and oral administration have been investigated and achieved different degrees of ...