Browsing by Author "Soto Moyano, Rubén"
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Pérez, Hernán; Soto Moyano, Rubén; Ruiz, Samuel; Hernández, Alejandro; Sierralta, Walter; Olivares, Ricardo; Núñez, Héctor; Flores, Osvaldo; Morgan, Carlos; López Valladares, Luis; Gatica, Arnaldo; Flores, Francisco J. (2010)Prenatal undernutrition induces hypertension later in life, possibly by disturbing the hypothalamo-pituitary-adrenal axis through programming decreased expression of hypothalamic glucocorticoid receptors. We examined the ...
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Pelissier Serrano, Teresa; Paeile, Carlos; Soto Moyano, Rubén; Saavedra, Hernán; Hernández, Alejandro (1990)The antinociceptive activity of the selective k opioid agonist U-50,488H, given intrathecally (i.t.) against chemically induced cutaneous pain in rats, was assessed from cumulative dose-response experiments and the formalin ...
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Pelissier Serrano, Teresa; Hernández, Alejandro; Mestre, Christine; Eschalier, Alain; Laurido, Claudio; Paeile, Carlos; Alvarez, Pedro; Soto Moyano, Rubén (2001)The antinociceptive effect of clomipramine was studied in monoarthritic rats by using the paw pressure test and the C-fiber-evoked reflex. Monoarthritis was produced by intra-articular injection of complete Freund's adjuvant ...
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Sáez Briones, Patricio; Soto Moyano, Rubén; Burgos, Héctor; Castillo, Amparo; Valladares Boasi, Luis; Morgan Sabat, Carlos; Pérez, Hernán; Barra, Rafael; Constandil, Luis; Laurido, Claudio; Hernández, Alejandro (Elsevier, 2015)Moderate reduction in dietary protein composition of pregnant rats from 25% to 8% casein, calorically compensated by carbohydrates, has been described as a ‘‘hidden malnutrition’’ because it does not alter body and brain ...
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Olivares Pérez-Montt, Ricardo; Soto Moyano, Rubén; Hernández, A.; Gil, J.; Gimeno, M.; Laborda, J.; Aboitiz Domínguez, Francisco Javier (2007)Adult rats malnourished prenatally with a low-protein, isocaloric diet showed smaller median fiber diameter of myelinated and unmyelinated fibers and a higher axonal density in the callosal splenium than controls. These ...
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Flores Bastías, Osvaldo Andrés (Universidad de Chile, 2004)Existen evidencias que el propanolol inhibe la potenciación sináptica de largo plazo en rebanadas de hipocampo, sugiriendo que este compuesto deprime la transducción de señales dependiente de la activación del receptor ...
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Laurido, Claudio; Pelissier Serrano, Teresa; Soto Moyano, Rubén; López Valladares, Luis; Flores, Francisco; Hernández, Alejandro (Lippincott Williams and Wilkins, 2002)Melatonin has been shown to exert potent antinociception but the sites and mechanisms of action underlying this effect have not yet been clarified. The effect of melatonin on spinal cord nociceptive transmission was studied ...
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Olivares Pérez-Montt, Ricardo; Soto Moyano, Rubén; Hernández, A.; Gil, J.; Gimeno, M.; Laborda, J.; Aboitiz, F. (Universidad de la Frontera, 2007)Adult rats malnourished prenatally with a low-protein, isocaloric diet showed smaller median fiber diameter of myelinated and unmyelinated fibers and a higher axonal density in the callosal splenium than controls. These ...
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Hernández, Alejandro; Soto Moyano, Rubén (1986)Bioelectrical responses evoked in the ventrolateral funiculus (VLF) of the spinal cord by electrical stimulation of the contralateral hind limb were studied following topical application of 1% morphine solution to the ...
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Hernández, Alejandro; Burgos, Héctor; Mondaca, Mauricio; Barra, Rafael; Núñez, Héctor; Pérez, Hernán; Soto Moyano, Rubén; Sierralta, Walter; Fernández, Victor; Olivares, Ricardo; López Valladares, Luis (Hindawi Publishing Corporation, 2008)Reduction of the protein content from 25 to 8% casein in the diet of pregnant rats results in impaired neocortical long-term potentiation (LTP) of the offspring together with lower visuospatial memory performance. The ...
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Arriagada, Osvaldo; Constandil, Luis; Hernández, Alejandro; Barra, Rafael; Soto Moyano, Rubén; Laurido, Claudio (2007)To investigate the contribution of glial cells in the spinal cord nociceptive transmission, the effect of intrathecally administered interleukin-1β (IL-1β) was studied in rats treated with the glial cell inactivator ...
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Soto Moyano, Rubén; Fernández, Victor; Sanhueza, Miguel; Belmar, Jorge; Kusch, Claudia; Pérez, Hernán; Ruiz, Samuel; Hernández, Alejandro (1999)There is evidence that severe malnutrition started during gestation and continued through lactation affects adversely the morphologic development of the neocortex leading to increased neuronal cell packing density and ...
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Núñez, Héctor; Ruiz, Samuel; Soto Moyano, Rubén; Navarrete, Mario; Valladares Boasi, Luis; White Ortiz, Allan; Pérez, Hernán (ELSEVIER IRELAND LTD, 2008-12-19)Prenatal undernutrition induces a variety of cardiovascular alterations inmammalswhenadults, including hypertension and hypercortisolism, which are thought to be caused by decreased glucocorticoid feedback control of the ...
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Soto Moyano, Rubén; Hernández, A.; Pérez, H.; Ruiz, S.; Carreño, P.; Belmar, J. (1993)It is known that nutritional restriction during gestation affects the growth of the corpus callosum. The present study was designed to evaluate whether prenatal malnutrition may alter, in the rat, the normal pattern of ...
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Constandil, Luis; Pelissier Serrano, Teresa; Soto Moyano, Rubén; Mondaca, Mauricio; Sáez, Hernán; Laurido, Claudio; Muñoz, Carlos; López, Nandy; Hernández, Alejandro (Elsevier Ireland Ltd, 2003)Cytokines produced by spinal cord glia after peripheral inflammation, infection or trauma have a relevant role in the maintenance of pain states. The effect of intrathecally administered interleukin-1β (IL-1β) on spinal ...
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Hernández, Alejandro; Laurido, Claudio; Mondaca, Mauricio; Pelissier Serrano, Teresa; Burgos, Hector; Soto Moyano, Rubén (2001)Desipramine-induced inhibition of spinal cord nociceptive transmission was studied in rats with or without lesion of the bulbospinal noradrenergic system by recording the C-fiber evoked nociceptive reflex from a hind limb. ...
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Pérez,; Ruiz, Daniela; Hernández, Alejandro; Soto Moyano, Rubén (1984)Cortical reactivity of the parietal association area was studied in undernourished rats after short and long rehabilitation periods. Undernutrition was induced during lactation by increasing litter size from 8 to 18 pups ...
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Belmar, Jorge; Carreño, Paz; Hernández, Alejandro; Soto Moyano, Rubén (Elsevier Inc., 1996)Experimental studies have shown that malnutrition early in life results in enhanced release of noradrenaline (NA) in the brain. The disturbed mechanism underlying this neurochemical disorder is poorly understood. To test ...
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Pérez, Hernán; Ruiz, Samuel; Hernández, Alejandro; Soto Moyano, Rubén (1985)Susceptibility to strychnine of somatosensory responses evoked in the prefrontal cortex was studied in normal and protein-malnourished rats in three groups. (a) The normal group was from mothers fed a 21% casein diet. (b) ...
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Soto Moyano, Rubén; Burgos, Héctor; Flores, Francisco; Valladares Boasi, Luis; Sierralta, Walter; Fernández Hidalgo, Víctor; Pérez, Hernán; Hernández, Paula; Hernández, Alejandro (PERGAMON-ELSEVIER SCIENCE LTD, 2006-10)Melatonin has been shown to inhibit long-term potentiation (LTP) in hippocampal slices of rats. Since LTP may be one of the main mechanisms by which memory traces are encoded and stored in the central nervous system, it ...