Browsing by Author "Soto Rifo, Ricardo Andrés"

Now showing items 1-15 of 15

    • Early versus deferred anti-SARS-CoV-2 convalescent plasma in patients admitted for COVID-19: A randomized ... 
      Balcells, María Elvira; Rojas, Luis; Le Corre, Nicole; Martínez Valdebenito, Constanza; Ceballos, María Elena; Ferrés, Marcela; Chang, Mayling; Vizcaya, Cecilia; Mondaca, Sebastián; Huete, Álvaro; Castro, Ricardo; Sarmiento, Mauricio; Villarroel, Luis; Pizarro, Alejandra; Ross, Patricio; Santander, Jaime; Lara, Bárbara; Ferrada, Marcela; Vargas Salas, Sergio Sebastián; Beltrán Pavez, Carolina Alejandra; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés; Caglevic, Christian; Mahave, Mauricio; Selman, Carolina; Gazitua, Raimundo; Briones, José Luis; Villarroel Espíndola, Franz; Balmaceda, Carlos; Espinoza, Manuel A.; Pereira, Jaime; Nervi, Bruno (Public Library Science, 2021)
      Background Convalescent plasma (CP), despite limited evidence on its efficacy, is being widely used as a compassionate therapy for hospitalized patients with COVID-19. We aimed to evaluate the efficacy and safety of ...
    • Identificación de ARNs no codificantes largos que forman parte de los complejos ribonucleoprotéicos del ... 
      Aguilera Cortés, Paulina Andrea (Universidad de Chile., 2021)
      Durante las etapas tardías del ciclo replicativo, el ARN genómico (ARNg) del Virus de la Inmunodeficiencia Humana de tipo 1 (VIH-1) se ensambla en complejos ribonucleoprotéicos (mRNPs) específicos cuya composición determina ...
    • Impacto de la metilación de adenosinas en el destino citoplásmico del ARN genómico de VIH-1 
      Pereira Montecinos, Camila Andrea (Universidad de Chile, 2020)
      El virus de la inmunodeficiencia humana tipo-1 (VIH-1) es el principal agente causal del síndrome de la inmunodeficiencia adquirida (SIDA). Su genoma corresponde a una molécula de ARN de simple hebra con polaridad positiva ...
    • Insights into neutralizing antibody responses in individuals exposed to SARS-CoV-2 in Chile 
      Beltrán Pavez, Carolina Alejandra; Riquelme Barrios, Sebastian Andres; Oyarzún Arrau, Aarón; Gaete Argel, Aracelly Janis; González Stegmaier, Roxana; Cereceda Solis, Karina; Aguirre, Adam; Travisany Flores, Dante Felipe; Palma Vejares, Ricardo Fernando; Barriga Pinto, Gonzalo Andrés; Gaggero Brillouet, Aldo Andres; Martínez Valdebenito, Constanza; Le Corre, Nicole; Ferres Garrido, Marcela Viviana; Balcells, María Elvira; Fernández, Jorge; Ramírez, Eugenio; Villarroel, Franz; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo Andrés (American Association for the Advancement of Science, 2021)
      Chile has one of the worst numbers worldwide in terms of SARS-CoV-2 positive cases and COVID-19-related deaths per million inhabitants; thus, characterization of neutralizing antibody (NAb) responses in the general population ...
    • N-6 -methyladenosine negatively regulates human respiratory syncytial virus replication 
      Figueroa, Fabián; Vega Gibson, Alonso Gonzalo; Catrileo, Joseline; Gaete Argel, Aracelly Janis; Riquelme Barrios, Sebastián Andrés; Alonso Palomares, Luis Antonio; Tapia Faúndes, Lorena; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo Andrés; Acevedo Acevedo, Mónica Loreto (Frontiers Media, 2021)
      N 6 -methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV). Here, we evaluated the impact of m6A writers, ...
    • Neutralizing antibody titers elicited by CoronaVac and BNT162b2 vaccines in health care workers with and ... 
      Wolff Reyes, Marcelo José; Acevedo Acevedo, Mónica Loreto; Núñez, María Antonieta; Lafourcade, Mónica; Gaete Argel, Aracelly Janis; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Oxford University Press, 2022)
      We report neutralizing antibody titers (NAbTs) elicited by CoronaVac and BNT162b2 vaccines in healthcare workers with and without prior SARS-CoV-2 infection using both a pseudotype-based assay and a commercial kit. NAbTs ...
    • Performance of SARS-CoV-2 rapid antigen test compared with real-time RT-PCR in asymptomatic individuals 
      Peña, Mónica; Ampuero Martínez, Manuel Andrés; Garcés, Carlos; Gaggero Brillouet, Aldo Andres; García, Patricia; Velásquez, María Soledad; Luza, Ricardo; Álvarez, Pía; Paredes, Fabio; Acevedo, Johanna; Farfán Urzúa, Mauricio Javier; Solari, Sandra; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Elsevier, 2021)
      Screening, testing and contact tracing plays a pivotal role in control of the COVID-19 pandemic. To enable this it is necessary to increase the testing capacity. This study compared a SARS-CoV-2 rapid antigen test (RAT) ...
    • Rol de la proteína Rev en el reclutamiento de factores celulares que promueven la síntesis de Gag del Virus ... 
      Rojas Araya, Bárbara Valeria (Universidad de Chile, 2023)
      Durante la infección causada por el virus de la inmunodeficiencia humana del tipo 1 (VIH-1), el ADN proviral es integrado en el genoma celular y luego la ARN polimerasa II sintetiza un único transcrito de 9-kb denominado ...
    • Role of epitranscriptomic and epigenetic modifications during the lytic and latent phases of herpesvirus infections 
      Soto, Abel A.; Ortiz, Gerardo; Contreras, Sofía; Soto Rifo, Ricardo Andrés; González, Pablo A. (MDPI, 2022)
      Herpesviruses are double-stranded DNA viruses occurring at a high prevalence in the human population and are responsible for a wide array of clinical manifestations and diseases, from mild to severe. These viruses are ...
    • Role of the human immunodeficiency virus type-1 (HIV-1) Rev protein in mitochondrial function of HEK293T cells 
      Saavedra Alarcón, Vicente Efraín (Universidad de Chile, 2022)
      It has been described that both antiretroviral therapy and infection by the human immunodeficiency virus type-1 (HIV-1) causes mitochondrial dysfunction in CD4+ T cells. In large-scale proteomics studies, the HIV-1 Rev ...
    • Serological study of CoronaVac vaccine and booster doses in Chile: immunogenicity and persistence of ... 
      Vargas, Leonardo; Valdivieso Berríos, Nicolás Alejandro; Tempio, Fabián; Simon Zegers, María Valeska; Sauma Mahaluf, Daniela Macarena; Valenzuela Pérez, Lucía Teresita; Beltrán Muñoz, Caroll Jenny; Castillo Delgado, Loriana Cecilia; Contreras Benavides, Ximena Stella; Acevedo Acevedo, Mónica Loreto; Acevedo, Johanna; González, Rafael I.; Valiente Echeverría, Fernando Andres; Soto Rifo, Ricardo Andrés; Rosemblatt Silber, Mario César; López Nitsche, Mercedes Natalia; Osorio Olivares, Fabiola Beatriz; Bono Merino, María Rosa (BMC, 2022)
      Background Chile was severely affected by COVID19 outbreaks but was also one of the first countries to start a nationwide program to vaccinate against the disease. Furthermore, Chile became one of the fastest countries to ...
    • Sertralina revierte diferencialmente sintomatología tipo depresiva inducida por estrés crónico en ratas ... 
      Aguayo Abarca, Felipe Ignacio (Universidad de Chile, 2023)
      La depresión mayor es una enfermedad mental que afecta aproximadamente a 5% de la población mundial. En Chile la cifra asciende a un 6.2%, sin embargo, se observa que la prevalencia es aproximadamente 5 veces mayor en ...
    • Surveillance of seasonal respiratory viruses among chilean patients during the COVID-19 pandemic 
      Alonso-Palomares, Luis A.; Cáceres, C. Joaquín; Tapia, Rodrigo; Aguilera Cortés, Paulina Andrea; Valenzuela, Santiago; Valiente Echeverría, Fernando; Soto Rifo, Ricardo Andrés; Gaggero Brillouet, Aldo Andrés; Barriga Pinto, Gonzalo Andrés (Wiley, 2021)
    • Tellurite promotes stress granules and nuclear SG-like assembly in response to oxidative stress and DNA damage 
      Gaete Argel, Aracelly Janis; Velásquez, Felipe; Márquez Badilla, Chantal Loretto; Rojas Araya, Bárbara; Bueno Nieto, Constanza Francisca; Marín Rojas, Josefina; Cuevas Zúñiga, Miguel; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Frontiers Media, 2021)
      Tellurium oxyanion, tellurite (TeO3-2), is a highly toxic compound for many organisms. Its presence in the environment has increased over the past years due to industrial manufacturing processes and has been associated ...
    • The landscape of IFN/ISG signaling in HIV-1-infected macrophages and its possible role in the HIV-1 latency 
      Rojas, Masyelly; Luz Crawford, Patricia; Soto Rifo, Ricardo Andrés; Reyes Cerpa, Sebastián; Toro Ascuy, Daniela (MDPI, 2021)
      A key characteristic of Human immunodeficiency virus type 1 (HIV-1) infection is the generation of latent viral reservoirs, which have been associated with chronic immune activation and sustained inflammation. Macrophages ...