Browsing by Author "Urzúa Tobar, Ulises"

Now showing items 1-10 of 10

    • Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated ... 
      Bahamondes, Verónica; Albornoz, Amelina; Aguilera, Sergio; Alliende, Cecilia; Molina, Claudio; Castro, Isabel; Urzúa Tobar, Ulises; Quest, Andrew F. G.; Barrera, María José; González, Sergio; Sánchez, Marianela; Härtel, Steffen; Hermoso Ramello, Marcela; Leyton Martínez, Cecilia; González Burgos, María Julieta (WILEY-BLACKWELL, 2011-10)
      Objective. Oral and ocular dryness are frequent and serious symptoms of Sjogren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
    • Development and validation of a microarray for the confirmation and typing of norovirus RT-PCR products 
      Mattison, Kirsten; Corneau, Nathalie; Berg, Ingvild; Bosch, Albert; Duizer, Erwin; Gutiérrez-Aguirre, Ion; L'Homme, Yvan; Lucero, Yalda; Luo, Zhiyao; Martyres, Alexander; Myrmel, Mette; O'Ryan Gallardo, Miguel; Pagotto, Franco; Sano, Daisuke; Svraka, Sanela; Urzúa Tobar, Ulises; Bidawi (2011)
      Noroviruses are implicated in many worldwide institutional, food and waterborne outbreaks each year. Genetic typing of isolates is valuable for monitoring outbreak spread as well as variation in circulating strains. ...
    • Mechanotransduction and epigenetic control in autoimmune diseases 
      González, Sergio; Aguilera, Sergio; Urzúa Tobar, Ulises; Quest, Andrew F. G.; Molina, Claudio; Alliende, Cecilia; Hermoso Ramello, Marcela; González Burgos, María Julieta (Elsevier, 2011)
      Differentiation of epithelial cells is required to define tissue architecture and appropriate function of these cells is associated with a specific pattern of gene expression. DNA methylation, post-translational modification ...
    • MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome 
      Sung Hsieh, Hsiao; Castro, I.; González, S.; Aguilera, S.; Smorodinsky, N. I.; Quest, Andrew F. G.; Bahamondes Lorca, Verónica; Alliende, Cecilia; Cortés, J.; Molina, Claudio; Urzúa Tobar, Ulises; Barrera, María José; Hermoso Ramello, Marcela; Herrera Cisterna, Luisa; Leyton Martínez, Cecilia; González Burgos, María Julieta (Wiley-Blackwell, 2015)
      OBJECTIVES: To evaluate the expression and localization of MUC1/SEC and MUC1/Y isoforms in labial salivary glands (LSG) from Sj€ogren’s syndrome patients (SS patients), as well as their in vitro expression induced by ...
    • Parity dependent hemosiderin and lipofuscin accumulation in the reproductively aged mouse ovary 
      Urzúa Tobar, Ulises; Chacón, Carlos; Espinoza, Renato; Martínez, Sebastián; Hernández, Nicole (Hindawi, 2018)
      The progressive decline of the ovarian follicle pool leads to reproductive ageing. The latter is accompanied by age-related disorders, including various types of cancer. In fact, the highest rates of ovarian cancer (OC) ...
    • Parity modulates the ovarian transcriptome and systemic inflammatory markers in estropausal mice 
      Urzúa Tobar, Ulises; Chacón, C.; Sarmiento, S.; Lizama, L.; Ampuero, S.; Marcelain Cubillos, Katherine; Villalobos, P.; González, M. J.; Romero Osses, Carmen (Lippincott Williams & Wilkins, 2015)
    • Pro-inflammatory cytokines enhance ERAD and ATF6 alpha pathway activity in salivary glands of Sjogren's ... 
      Barrera, María José; Aguilera, Sergio; Castro, Isabel; Cortés Araya, Juan Eliecer; Bahamondes Lorca, Verónica; Quest, Andrew F. G.; Molina, Claudio; González, Sergio; Hermoso Ramello, Marcela; Urzúa Tobar, Ulises; Leyton, Cecilia; González Burgos, María Julieta (Elsevier, 2016)
      Salivary gland (SG) acinar-cells are susceptible to endoplasmic reticulum (ER) stress related to their secretory activity and the complexity of synthesized secretory products. SGs of Sji5gren's syndrome patients (SS)-patients ...
    • Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular ... 
      Barrera, María José; Aguilera, Sergio; Veerman, Enno; Quest, Andrew F. G.; Díaz Jiménez, David; Urzúa Tobar, Ulises; Cortés Araya, Juan Eliecer; González, Sergio; Castro, Isabel; Molina, Claudio; Bahamondes, Verónica; Leyton, Cecilia; Hermoso Ramello, Marcela; González Burgos, María Julieta (Oxford Univ Press, 2015)
      Objectives. A hallmark characteristic of SS patients is the ectopic presence of the mucins MUC5B and MUC7 in the extracellular matrix of salivary glands that have lost apical basolateral acinar-cell polarity. This study ...
    • Sjögren’s syndrome and the epithelial target: A comprehensive review 
      Barrera, M. J.; Bahamondes Cornejo, Valeria Cristina; Sepúlveda, D.; Quest, Andrew F. G.; Castro, I.; Cortés, J.; Aguilera, S.; Urzúa Tobar, Ulises; Molina, C.; Pérez, P.; Ewert, P.; Alliende, C.; Hermoso Ramello, Marcela; González, S.; Leyton Blanca, Cristina; González, M. J. (Elsevier, 2013)
      The most difficult component in our understanding of human autoimmunity remains a rigorous dissection of etiological events. Indeed, the vast literature on autoimmune diseases focuses on the inflammatory response, with ...
    • Small RNA expression profiling reveals hsa-miR-181d-5p downregulation associated with TNF-α overexpression ... 
      Castro Masso, Isabel Verónica; Carvajal Garcés, Patricia Alejandra; Jara, Daniela; Aguilera, Sergio; Heathcote Pérez, Benjamín Norman; Barrera, María José; Aliaga Tobar, Víctor Manuel; Maracaja Coutinho, Vinicius; Urzúa Tobar, Ulises; Quest, Andrew Frederick Geoffery; González, Sergio; Claudio, Molina; Hermoso, Marcela Alejandra; González Burgos, María Julieta (Frontiers Media, 2022)
      MicroRNAs (miRNAs) are small non-coding RNAs (sRNA), that alter gene expression by binding to target messenger RNAs (mRNAs) and repressing translation. Dysregulated miRNA expression has been implicated in the pathogenesis ...