Browsing by Author "Varela Figueroa, Nelson"
Now showing items 1-8 of 8
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As3MT and GST Polymorphisms Influencing Arsenic Metabolism in Human Exposure to Drinking Groundwater (MDPI, 2020)The urinary arsenic metabolites may vary among individuals and the genetic factors have been reported to explain part of the variation. We assessed the influence of polymorphic variants of Arsenic-3-methyl-transferase and ...
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(Universidad de Chile, 2020)La tuberculosis es una enfermedad infectocontagiosa producida principalmente por la bacteria Mycobaterium tuberculosis. Actualmente, según la OMS, tiene a un tercio de la población mundial contagiada. En Chile, se estima ...
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(Elsevier, 2001)CYP1A1, CYP2E1 and GSTM1 polymorphisms were evaluated in Chilean healthy controls and lung cancer patients. In the Chilean healthy group, frequencies of CYP1A1 variant alleles for MspI (m2 or CYP1A1*2A) and ile/val (val ...
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(Universidad de Chile, 2019)Cuando ocurre un daño tisular o infeccioso en el corazón se inicia un conjunto de respuestas que llevarán a la reparación del tejido dañado. En esta situación, adquiere protagonismo un tipo celular cardiaco llamado fibroblasto ...
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(Elsevier, 1999)Many investigators have reported an association between genetic polymorphisms of cytochromes P-450 CYP2E1, CYP1A1 or glutathione S-transferase Mu (GSTM1) and susceptibility to lung cancer. However, pronounced interethnic ...
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(2006)Pharmacogenetics is the study of genetically determined variations in the response to drugs and toxic agents, and their implications on disease. Recently, the discipline has acquired great relevancy due to the development ...
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(Sociedad Médica de Santiago, 2017)Pharmacogenomics is an emergent field aimed at tailoring pharmacological therapy. Genetic polymorphisms can modify the expression and function of enzymes and proteins involved in drug metabolism, affecting absorption, ...
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(2010)Changes in bioavailability of anticonvulsant drugs such as topiramate may cause loss of or worsened seizure control. Thus, the purpose of this study was to evaluate, in a double-blind crossover design, the bioavailability ...
