Browsing by Author "Verdejo, Hugo E."

Now showing items 1-6 of 6

    • Atrial Function Assessed by Speckle Tracking Echocardiography Is a Good Predictor of Postoperative Atrial ... 
      Verdejo, Hugo E.; Becerra, Elia; Zalaquett Sepúlveda, Ricardo; Campo, Andrea del; García Nannig, Lorena; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Marín, Arnaldo; Castro, Pablo F.; Lavandero González, Sergio; Gabrielli, Luigi A.; Corbalán, Ramón (Wiley & Sons, 2016)
      ObjectiveAdvanced age is an independent predictor of postoperative atrial fibrillation (POAF) in patients undergoing coronary artery bypass surgery. We evaluated whether left atrial (LA) dysfunction assessed by strain ...
    • Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy 
      Westermeier, Francisco; Navarro Márquez, Mario F.; López Crisosto, Camila; Bravo Sagua, Roberto; Quiroga Lagos, Clara; Bustamante, Mario; Verdejo, Hugo E.; Zalaquett Sepúlveda, Ricardo; Ibacache, Mauricio; Parra Ortíz, María Valentina; Castro, Pablo F.; Rothermel, Beverly A.; Hill, Joseph A.; Lavandero González, Sergio (Elsevier, 2015)
      Diabetic cardiomyopathy (DCM) is a common consequence of longstanding type 2 diabetes mellitus (T2DM) and encompasses structural, morphological, functional, and metabolic abnormalities in the heart.Myocardial energy metabolism ...
    • Effects of Trimetazidine in Nonischemic Heart Failure: A Randomized Study 
      Winter, José Luis; Castro, Pablo F.; Quintana, Juan Carlos; Altamirano, Rodrigo; Enriquez, Andrés; Verdejo, Hugo E.; Jalil Milad, Jorge; Mellado, Rose Marie; Concepción, Roberto; Sepúlveda, Pablo; Rossel Mariángel, Víctor; Sepúlveda Morales, Luis; Chiong Lay, Mario; García Nannig, Lorena; Lavandero González, Sergio (Elsevier, 2014)
      Objectives: Heart failure (HF) is associated with changes in myocardial metabolism that lead to impairment of contractile function. Trimetazidine (TMZ) modulates cardiac energetic efficiency and improves outcomes in ...
    • Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases ... 
      Bravo Méndez, Roberto; Vicencio Bustamante, José Miguel; Parra Ortíz, María Valentina; Troncoso, Rodrigo; Muñoz, Juan Pablo; Bui, Michael; Quiroga Lagos, Clara; Rodríguez Villarroel, Andrea Elizabeth; Verdejo, Hugo E.; Ferreira Parker, Jorge; Iglewski, Miriam; Chiong Lay, Mario; Simmen, Thomas; Zorzano, Antonio; Hill, Joseph A.; Rothermel, B. A.; Szabadkai, Gyorgy; Lavandero González, Sergio (COMPANY OF BIOLOGISTS LTD., 2011-07-15)
      Increasing evidence indicates that endoplasmic reticulum (ER) stress activates the adaptive unfolded protein response (UPR), but that beyond a certain degree of ER damage, this response triggers apoptotic pathways. The ...
    • Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through ... 
      Campo Sfeir, Andrea Estefanía del; Parra Ortíz, María Valentina; Vásquez Trincado, César Alonso; Gutiérrez, Tomás; Morales, Pablo E.; López Crisosto, Camila; Bravo Sagua, Roberto; Navarro Márquez, Mario F.; Verdejo, Hugo E.; Contreras Ferrat, Ariel Eduardo; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Lavandero González, Sergio (American Physiological Society, 2014)
      Insulin is a major regulator of glucose metabolism, stimulating its mitochondrial oxidation in skeletal muscle cells. Mitochondria are dynamic organelles that can undergo structural remodeling in order to cope with these ...
    • Xanthine-oxidase inhibitors and statins in chronic heart failure: Effects on vascular and functional parameters 
      Greig, Douglas; Alcaíno Gálvez, Hernán Alejandro; Castro Gálvez, Pablo; García Nannig, Lorena; Verdejo, Hugo E.; Navarro, Mario; López, Rafael; Mellado, Rose Marie; Tapia Mamani, Fabiola Karina; Gabrielli, Luigi A.; Nogerol, Camilo; Chiong Lay, Mario; Godoy, Iván; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2011-04)
      Increased oxidative stress in heart failure (HF) leads to inflammation and endothelial dysfunction (ED). Both statins and allopurinol have known anti-oxidant properties, but their utility in HF has not been fully assessed.