Browsing by Subject "Alzheimer"

Now showing items 1-11 of 11

    • Alicia 
      Aracena Benavente, Valeska Carmen; Chacana Pérez, Constanza Belén; Madariaga Quiroz, Ramón Gustavo; Riffo Lizana, Alexander Philip (2016)
      Alicia (60) trabaja cuidando a una anciana que sufre de Alzheimer en un departamento de Providencia. Su rutina diaria se compone en los cuidados que le da a la señora y el ver las telenovelas brasileñas.Un día la señora ...
    • Alzheimer: El Chile olvidado 
      Labra, Nicolás; Pulgar, Nicole (Universidad de Chile, 2014-05)
      Chile se encuentra en una etapa de cambios socioculturales, económicos y demográficos, y es justamente en este último punto donde se entrelazan dos situaciones de gran relevancia para el presente y para el futuro del país. ...
    • Dementia in Latin America: Epidemiological Evidence and Implications for Public Policy 
      Custodio, Nilton; Wheelock, Ana; Thumala Dockendorff, Daniela Cecilia; Slachevsky Chonchol, Andrea (Frontiers media SA, 2017)
      Population aging is among the most important global transformations. Today, 12% of the world population is of age 60 and over and by the middle of this century this segment will represent 21.5%. The increase in population ...
    • Experiencias de mujeres cuidadoras de familiares mayores en situación de dependencia: Trayectorias de ... 
      Barría Zurita, Isidora (Universidad de Chile, 2021)
      La siguiente Memoria de Título se orienta a conocer la problemática del cuidado en Chile, a partir de las transformaciones que se han observado en torno al envejecimiento y a la organización de la familia en los últimos ...
    • GERO cohort protocol, Chile, 2017–2022: community-based cohort of functional decline in subjective cognitive ... 
      Slachevsky Chonchol, Andrea; Zitko, Pedro; Martínez Pernía, David; Forno, Gonzalo; Court, Felipe A.; Lillo, Patricia; Villagra Castro, Roque; Durán Aniotz, Claudia Andrea; Parrao, Teresa; Assar, Rodrigo; Orellana, Paulina; Toledo, Carolina; Rivera, Rodrigo; Ibáñez, Agustín; Parra, Mario A.; González Billault, Christian; Amieva, Helena; Thumala, Daniela (BMC, 2020)
      Background: With the global population aging and life expectancy increasing, dementia has turned a priority in the health care system. In Chile, dementia is one of the most important causes of disability in the elderly ...
    • Heterocyclic curcumin derivatives of pharmacological interest: Recent progress 
      Martínez Cifuentes, Maximiliano; Weiss López, Boris; Santos, Leonardo S.; Araya Maturana, Ramiro (Bentham Science Publishers B.V., 2015)
      © 2015, Bentham Science Publishers. Curcumin, a natural yellow polyphenol, is isolated from the herb Curcuma longa L. (turmeric), a member of the ginger family. It has been extensively studied due to their multiple ...
    • Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia ... 
      Ponce, Daniela P.; Salech Morales, Felipe; San Martín Rovirosa, Carol; Silva, Monica; Xiong, Chengjie; Roe, Catherine M.; Henríquez, Mauricio; Quest, Andrew F. G.; Behrens Pellegrino, María Isabel (Bentham Science Publishers B.V., 2014)
      © 2014 Bentham Science Publishers.We previously reported on enhanced susceptibility to death of lymphocytes from Alzheimer’s disease (AD) patients when exposed to hydrogen peroxide (H2O2)-induced oxidative stress and an ...
    • Inverse susceptibility to oxidative death of lymphocytes obtained from Alzheimer's patients and skin cancer ... 
      Behrens Pellegrino, María Isabel; Silva, Monica; Salech Morales, Felipe; Ponce, Daniela P.; Merino, Daniela; Sinning, Mariana; Xiong, Chengjie; Roe, Catherine M.; Quest, Andrew F. G. (2012)
      A paucity of cancer in individuals with Alzheimer's disease (AD) and low rates of AD in cancer survivors has been reported in epidemiological studies. Deregulation in opposite directions of biological mechanisms, such as ...
    • Overexpression of amyloid precursor protein increases copper content in HEK293 cells 
      Suazo, Miriam; Hodar, Christian; Morgan, Carlos; Cerpa, Waldo; Cambiazo, Verónica; Inestrosa, Nibaldo C.; Gonzalez, Mauricio (2009)
      Amyloid precursor protein (APP) is a transmembrane glycoprotein widely expressed in mammalian tissues and plays a central role in Alzheimer's disease. However, its physiological function remains elusive. Cu2+ binding and ...
    • Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents 
      Mosnaim, Aron D.; Ranade, Vasant V.; Wolf, Marion E.; Puente, Javier; Antonieta Valenzuela, M. (2006)
      The chemical structure of phenothiazine provides a most valuable molecular template for the development of agents able to interact with a wide variety of biological processes. Synthetic phenothiazines (with aliphatic, ...
    • UHPLC-MS metabolomic fingerprinting, antioxidant, and enzyme inhibition activities of himantormia lugubris ... 
      Areche Medina, Carlos Alberto; Romero Parra, Javier Hernán; Sepúlveda, Beatriz; García Beltrán, Olimpo; Simirgiotis, Mario J. (MDPI, 2022)
      Himantormia lugubris is a Chilean native small lichen shrub growing in the Antarctica region. In this study, the metabolite fingerprinting and the antioxidant and enzyme inhibitory potential from this species and its four ...