Browsing by Subject "CD73"
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(Frontiers Media, 2021)CD39 and CD73 are ectoenzymes that dephosphorylate ATP into its metabolites; ADP, AMP, and adenosine, and thus are considered instrumental in the development of immunosuppressive microenvironments. We have previously shown ...
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(Frontiers Media, 2021)Ecto-5 '-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is ...
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Rol de CD73 en el fenotipo y la producción de citoquinas de células NK murinas expandidas in vitro (Universidad de Chile, 2022)Las células NK son linfocitos innatos que son muy relevantes en la respuesta inmune antitumoral ya que pueden reconocer y eliminar directamente las células tumorales, sin una estimulación previa. Dentro del microambiente ...