Browsing by Subject "Innate immunity"

Now showing items 1-8 of 8

    • Desired immune response characteristics in an RSV vaccine: What infants tell us 
      Reed, Jennifer L.; Avendaño, Luis; Velozo, Luis; Welliver, Robert C. (Elsevier, 2009)
      Respiratory syncytial virus (RSV) represents an important target for vaccine development. The design of an effective vaccine for infants is hindered by a lack of knowledge of the nature of the protective immune response ...
    • Determinants of Periodontal/Periapical Lesion Stability and Progression 
      Cavalla Ruiz, Franco; Letra, A.; Silva, R. M.; Garlet, G. P. (SAGE, 2020)
      Periodontal and periapical lesions are infectious inflammatory osteolitytic conditions in which a complex inflammatory immune response mediates bone destruction. However, the uncertainty of a lesion's progressive or stable ...
    • Innate immune cells' contribution to systemic lupus erythematosus 
      Herrada, Andrés A.; Escobedo, Noelia; Iruretagoyena, Mirentxu; Valenzuela, Rodrigo A.; Burgos, Paula I.; Cuitino, Loreto; Llanos, Carolina (Frontiers Media S.A., 2019)
      Copyright © 2019 Herrada, Escobedo, Iruretagoyena, Valenzuela, Burgos, Cuitino and Llanos.Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of autoantibodies against nuclear ...
    • Intestinal Inflammation Induced by Soybean Meal Ingestion Increases Intestinal Permeability and Neutrophil ... 
      Solis, Camila J.; Hamilton, M. Kristina; Caruffo, Mario; García López, Juan P.; Navarrete Wallace, Paola; Guillemin, Karen; Feijoo, Carmen G. (Frontiers Media, 2020)
      Intestinal inflammation is a condition shared by several intestinal chronic diseases, such as Crohn's disease and ulcerative colitis, with severely detrimental consequences in the long run. Current mammalian models have ...
    • Macrophages skew towards M1 profile through reduced CD163 expression in symptomatic apical periodontitis 
      Veloso Matta, Pablo; Fernández, Alejandra; Terraza, Claudia; Álvarez Rivas, Carla; Vernal Astudillo, Rolando; Escobar Álvarez, Alejandro; Hernández Ríos, Emma (Springer, 2020)
      Objectives To explore the macrophage profiles in symptomatic and asymptomatic forms of AP through phenotypic and functional analyses. Material and methods Cross-sectional study. Apical tissue/lesion samples were collected ...
    • Stage-specific role of interferon-gamma in experimental autoimmune encephalomyelitis and multiple sclerosis 
      Arellano, Gabriel; Ottum, Payton A.; Reyes, Lilian I.; Burgos, Paula; Naves, Rodrigo (Frontiers Media, 2015)
      The role of interferon (IFN)-gamma in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), has remained as an enigmatic paradox for more than 30 years. Several studies attribute ...
    • The damage signals hypothesis of Alzheimer's disease pathogenesis 
      Fernández, Jorge A.; Rojo, Leonel; Kuljis, Rodrigo O.; Maccioni Baraona, Ricardo (IOS Press, 2008)
      Virtually none of the hypotheses on Alzheimer's disease (AD) pathogenesis address the earliest events that trigger the molecular alterations that precede cerebral degeneration and account for the diversity of risk factors ...
    • Toll-like receptors are key participants in innate immune responses 
      Arancibia, Sergio A.; Beltrán, Caroll J.; Aguirre, Isabel M.; Silva, Paulina; Peralta, Alexis L.; Malinarich, Frano; Hermoso Ramello, Marcela (Society of Biology of Chile, 2007)
      During an infection, one of the principal challenges for the host is to detect the pathogen and activate a rapid defensive response. The Toll-like family of receptors (TLRs), among other pattern recognition receptors (PRR), ...