Now showing items 1-10 of 10

    • Luis Ignacio Becerra Chávez (Universidad de Chile, 2023)
      Durante la última década, se ha observado que la enfermedad del hígado graso no alcohólico (EHGNA) en el embarazo se ha triplicado, constituyendo un problema de salud pública, ya que aumenta el riesgo de desarrollar ...
    • Luarte Navarro, Alejandro; Henzi, Roberto; Fernández, Anllely; Gaete, Diego; Cisternas, Pablo; Pizarro, Matías; Batiz, Luis Federico; Villalobos, Isabel; Masalleras, Matías; Vergara, Rodrigo; Varas Godoy, Manuel; Abarzúa Catalán, Lorena; Herrera Molina, Rodrigo; Lafourcade, Carlos; Wyneken, Úrsula (MDPI, 2020)
      In the last few decades, it has been established that astrocytes play key roles in the regulation of neuronal morphology. However, the contribution of astrocyte-derived small extracellular vesicles (sEVs) to morphological ...
    • Di Genova, Alex; Nardocci, Gino; Maldonado Agurto, Rodrigo Alejandro; Hodar Quiroga, Christian Eduardo; Valdivieso, Camilo; Morales, Pamela; Gajardo, Felipe; Marina, Raquel; Gutiérrez, Rodrigo A.; Orellana, Ariel; Cambiazo Ayala, Liliana Verónica; González Canales, Mauricio Alejandro; Glavic Maurer, Alvaro Alberto; Mendez Torres, Marco Antonio; Maass Sepúlveda, Alejandro Eduardo; Allende Connelly, Miguel Luis; Montecino, Martin A. (Academic Press Inc Elsevier Science, 2021)
      Orestias ascotanensis (Cyprinodontidae) is a teleost pupfish endemic to springs feeding into the Ascotan saltpan in the Chilean Altiplano (3,700 m.a.s.l.) and represents an opportunity to study adaptations to high-altitude ...
    • Matamala, José Manuel; Arias Carrasco, Raul; Sánchez, Carolina; Uhrig, Markus; Bargsted, Leslie; Matus, Soledad; Maracaja Coutinho, Vinicius; Abarzua, Sebastián; Van Zundert, Brigitte; Verdugo Latorre, Renato; Manque, Patricio; Hetz Flores, Claudio (Elsevier, 2018)
      The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...
    • Tittarelli, Andrés; Navarrete, Mariela; Lizana, Marcelo; Hofmann Vega, Francisca; Salazar Onfray, Flavio (MDPI, 2020)
      Alterations in microRNA (miRNA) profiles, induced by tumor microenvironment stressors, like hypoxia, allow cancer cells to acquire immune-resistance phenotypes. Indeed, hypoxia-induced miRNAs have been implicated in cancer ...
    • Duroux Richard, Isabelle; Cuenca, Jimena; Ponsolles, Clara; Badilla Piñeiro, Alejandro; Gonzalez, Fernando; Roubert, Christine; Areny, Roser; Chea Vine, Rosa; Pefaur, Jacqueline; Pers, Yves-Marie; Figueroa, Fernando E.; Jorgensen, Christian; Khoury, Maroun; Apparailly, Florence (MDPI AG, 2015)
      MicroRNAs control the differentiation and function of B cells, which are considered key elements in the pathogenesis of systemic lupus erythematosus (SLE). However, a common micro(mi)RNA signature has not emerged since ...
    • López, Paulina; Castro, Andrea; Florez, M.; Miranda, Karen; Aranda, Pilar; Sánchez-González, Cristina; Llopis, Juan; Arredondo Olguin, Miguel Armando (Frontiers Media S.A., 2018-05-29)
      Obesity is characterized by mild chronic inflammation that is linked with impaired iron homeostasis. Studies in human and murine show that there is a transgenerational epigenetic inheritance via the gametes in obesity; ...
    • Daniela Paz Jara Araya (Universidad de Chile, 2023)
      El síndrome de Sjögren (SS) es una enfermedad autoinmune e inflamatoria que afecta principalmente a las glándulas salivales (GS). Se caracteriza por una sobreactivación de la vía de interferones de tipo I (IFNs I), citoquinas ...
    • Varela Figueroa, Nelson; Lanas, Fernando; Salazar, Luis; Zambrano Coloma, Tomás (Frontiers Media, 2020)
      In-stent restenosis corresponds to the diameter reduction of coronary vessels following percutaneous coronary intervention (PCI), an invasive procedure in which a stent is deployed into the coronary arteries, producing ...