Browsing by Subject "MicroRNAs"

Now showing items 1-8 of 8

    • Astrocyte-derived small extracellular vesicles regulate dendritic complexity through miR-26a-5p activity 
      Luarte Navarro, Alejandro; Henzi, Roberto; Fernández, Anllely; Gaete, Diego; Cisternas, Pablo; Pizarro, Matías; Batiz, Luis Federico; Villalobos, Isabel; Masalleras, Matías; Vergara, Rodrigo; Varas Godoy, Manuel; Abarzúa Catalán, Lorena; Herrera Molina, Rodrigo; Lafourcade, Carlos; Wyneken, Úrsula (MDPI, 2020)
      In the last few decades, it has been established that astrocytes play key roles in the regulation of neuronal morphology. However, the contribution of astrocyte-derived small extracellular vesicles (sEVs) to morphological ...
    • Genome sequencing and transcriptomic analysis of the andean killifish orestias ascotanensis reveals adaptation ... 
      Di Genova, Alex; Nardocci, Gino; Maldonado Agurto, Rodrigo Alejandro; Hodar Quiroga, Christian Eduardo; Valdivieso, Camilo; Morales, Pamela; Gajardo, Felipe; Marina, Raquel; Gutiérrez, Rodrigo A.; Orellana, Ariel; Cambiazo Ayala, Liliana Verónica; González Canales, Mauricio Alejandro; Glavic Maurer, Alvaro Alberto; Mendez Torres, Marco Antonio; Maass Sepúlveda, Alejandro Eduardo; Allende Connelly, Miguel Luis; Montecino, Martin A. (Academic Press Inc Elsevier Science, 2021)
      Orestias ascotanensis (Cyprinodontidae) is a teleost pupfish endemic to springs feeding into the Ascotan saltpan in the Chilean Altiplano (3,700 m.a.s.l.) and represents an opportunity to study adaptations to high-altitude ...
    • Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral ... 
      Matamala, José Manuel; Arias Carrasco, Raul; Sánchez, Carolina; Uhrig, Markus; Bargsted, Leslie; Matus, Soledad; Maracaja Coutinho, Vinicius; Abarzua, Sebastián; Van Zundert, Brigitte; Verdugo Latorre, Renato; Manque, Patricio; Hetz Flores, Claudio (Elsevier, 2018)
      The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...
    • Hypoxic Melanoma Cells Deliver microRNAs to Dendritic Cells and Cytotoxic T Lymphocytes through Connexin-43 ... 
      Tittarelli, Andrés; Navarrete, Mariela; Lizana, Marcelo; Hofmann Vega, Francisca; Salazar Onfray, Flavio (MDPI, 2020)
      Alterations in microRNA (miRNA) profiles, induced by tumor microenvironment stressors, like hypoxia, allow cancer cells to acquire immune-resistance phenotypes. Indeed, hypoxia-induced miRNAs have been implicated in cancer ...
    • MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers 
      Duroux Richard, Isabelle; Cuenca, Jimena; Ponsolles, Clara; Badilla Piñeiro, Alejandro; Gonzalez, Fernando; Roubert, Christine; Areny, Roser; Chea Vine, Rosa; Pefaur, Jacqueline; Pers, Yves-Marie; Figueroa, Fernando E.; Jorgensen, Christian; Khoury, Maroun; Apparailly, Florence (MDPI AG, 2015)
      MicroRNAs control the differentiation and function of B cells, which are considered key elements in the pathogenesis of systemic lupus erythematosus (SLE). However, a common micro(mi)RNA signature has not emerged since ...
    • MicroRNAs and response to statins in patients with hypercholesterolemia: from basic research to precision medicine 
      Zambrano Coloma, Tomás; Salazar, Luis A. (Future Medicine, 2018-06)
    • MiR-155 and miR-122 expression of spermatozoa in obese subjects 
      López, Paulina; Castro, Andrea; Florez, M.; Miranda, Karen; Aranda, Pilar; Sánchez-González, Cristina; Llopis, Juan; Arredondo Olguin, Miguel Armando (Frontiers Media S.A., 2018-05-29)
      Obesity is characterized by mild chronic inflammation that is linked with impaired iron homeostasis. Studies in human and murine show that there is a transgenerational epigenetic inheritance via the gametes in obesity; ...
    • The Current state of MicroRNAs as restenosis biomarkers 
      Varela Figueroa, Nelson; Lanas, Fernando; Salazar, Luis; Zambrano Coloma, Tomás (Frontiers Media, 2020)
      In-stent restenosis corresponds to the diameter reduction of coronary vessels following percutaneous coronary intervention (PCI), an invasive procedure in which a stent is deployed into the coronary arteries, producing ...