Browsing by Subject "Nifurtimox"
Now showing items 1-12 of 12
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(BioMed Central, 2015)Background: Outbreaks of acute Chagas disease associated with oral transmission are easily detected nowadays with trained health personnel in areas of low endemicity, or in which the vector transmission has been interrupted. ...
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(Universidad de ChileCyberDocs, 2010)
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(Society of Biology of Chile, 2010)There are approximately 7.8 million people in Latin America, including Chile, who suffer from Chagas disease and another 28 million who are at risk of contracting it. Chagas is caused by the flagellate protozoan Trypanosoma ...
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(2010)Chagas disease must be treated in all its stages: acute, indeterminate, chronic, and initial and middle determinant chronic, due to the fact that DNA of the parasite can be demonstrated by PCR in chronic cases, where optical ...
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(Society of Biology of Chile, 2002)The aim of the present study was to study the trypanocidal activity of nanoparticles loaded with nifurtimox in comparison with the free drug against Trypanosoma cruzi, responsible for Chagas' disease. Ethylcyanoacrylate ...
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(Society of Biology of Chile, 2004)Proteins rich in sulfhydryl groups, such as metallothionein, are present in several strains of the parasite Trypanosoma cruzi, the etiological agent of Chagas' disease. Metallothionein-like protein concentrations ranged ...
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(Universidad de Chile, 2010)La enfermedad de Chagas persiste como un problema de salud pública en Latinoamérica. Es producida por el protozoo flagelado Trypanosoma cruzi, el cual ha sido clasificado en 6 Unidades de Tipificación Discreta (DTUs), Tc ...
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(Elsevier, 1995)The cyclic voltammetric (CV) behaviour of nifurtimox was studied. The addition of aprotic solvent (DMF) to nifurtimox in an aqueous citrate buffer system was examined. Qualitatively this results in separation of the initial ...
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(Korean Society for Parasitology and Tropical Medicine, 2019)In the indeterminate chronic period of Chagas disease (ChD) the treatment has not been conclusive, because the serological negativization requires many years. This study aims to evaluate the efficacy of nifurtimox (NF) in ...
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(Springer-Verlag, 1992)The pharmacokinetics of nifurtimox, a drug used in the treatment of Trypanosoma cruzi infections, has been studied in seven patients with chronic renal failure undergoing haemodialysis, and in seven healthy subjects. Each ...
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(Elsevier, 2014)Nifurtimox (Nfx) and Benznidazole (Bnz) are the only available drugs in use for the treatment of Chagas disease. These drugs are recommended but not fully validated in evidence-based medicine and reports about the ...
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(Elsevier, 2017)Although Chagas disease has existed for at least 9000 years, its treatment is recent: the internationally accepted drugs nifurtimox and benznidazole date from the 1970s. Both drugs are effective in acute cases, in congenital ...