Browsing by Author "Machens, Hans Günther"

Now showing items 1-6 of 6

    • Enhanced Collateral Growth by Double Transplantation of Gene-Nucleofected Fibroblasts in Ischemic Hindlimb of Rats 
      Zhang, Ziyang; Slobodianski, Alex; Ito, Wulf D.; Arnold, Astrid; Nehlsen, Jessica; Weng, Shaoxiang; Lund, Natalie; Liu, Jihong; Egaña, José T; Lohmeyer, Jörn A.; Müller, Daniel F.; Machens, Hans Günther (PUBLIC LIBRARY SCIENCE, 2011-04-25)
      Background: Induction of neovascularization by releasing therapeutic growth factors is a promising application of cell-based gene therapy to treat ischemia-related problems. In the present study, we have developed a new ...
    • A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo 
      Schenck, Thilo L.; Chávez, Myra N.; Condurache, Alexandru P.; Hopfner, Úrsula; Rezaeian, Farid; Machens, Hans Günther; Egaña, José T. (JOURNAL OF VISUALIZED EXPERIMENTS, 2014)
      Insufficient vascularization is considered to be one of the main factors limiting the clinical success of tissue-engineered constructs. In order to evaluate new strategies that aim at improving vascularization, reliable ...
    • In Vitro Evaluation of Scaffolds for the Delivery of Mesenchymal Stem Cells to Wounds 
      Wahl, Elizabeth A.; Fierro, Fernando A.; Peavy, Thomas R.; Hopfner, Úrsula; Dye, Julian F.; Machens, Hans Günther; Egaña, José T.; Schenck, Thilo L. (Hindawi, 2015)
      Mesenchymal stemcells (MSCs) have been shown to improve tissue regeneration in several preclinical and clinical trials. These cells have been used in combination with three-dimensional scaffolds as a promising approach in ...
    • Photosynthetic biomaterials: A pathway towards autotrophic tissue engineering 
      Schenck, Thilo Ludwig; Hopfner, Úrsula; Chávez, Myra Noemi; Machens, Hans Günther; Somlai Schweiger, Ian Andreas; Giunta, Riccardo Enzo; Viola Bohne, Alexandra; Nickelsen, Jörg; Allende Connelly, Miguel; Egaña, José Tomás (Elsevier, 2015)
      Engineered tissues are highly limited by poor vascularization in vivo, leading to hypoxia. In order to overcome this challenge, we propose the use of photosynthetic biomaterials to provide oxygen. Since photosynthesis is ...
    • The role of single cell derived vascular resident endothelial progenitor cells in the enhancement of ... 
      Zhang, Ziyang; Ito, Wulf D.; Hopfner, Úrsula; Böhmert, Björn; Kremer, Mathias; Reckhenrich, Ann K.; Harder, Yves; Lund, Natalie; Kruse, Charli; Machens, Hans Günther; Egaña, José T. (Elsevier, 2011)
      Increasing evidence suggests that vascular resident endothelial progenitor cells (VR-EPCs) are present in several organs, playing an important role in postnatal neovascularization. Here, we isolated and characterized VR-EPCs ...
    • Towards Autotrophic Tissue Engineering: Photosynthetic Biomaterials for Tissue Regeneration 
      Rosas, M. N. C.; Schenck, Thilo L.; Hopfner, Úrsula; Centeno, C.; Machens, Hans Günther; Somlai Schweiger, Ian Andreas; Heikenwaelder, M.; Bono Merino, María Rosa; Schwarz, C.; Nickelsen, Jörg; Allende Connelly, Miguel; Egaña, J. T. (Mary Ann Liebert, 2015)