Browsing by Subject "UNFOLDED PROTEIN RESPONSE"

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    • BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1 alpha 
      Lisbona, Fernanda; Rojas Rivera, Diego; Thielen, Peter; Zamorano, Sebastián; Todd, Derrick; Martinon, Fabio; Glavic Maurer, Álvaro; Kress, Christina; Lin, Jonathan H.; Walter, Peter; Reed, John C.; Glimcher, Laurie H.; Hetz Flores, Claudio (CELL PRESS, 2009-03-27)
      Adaptation to endoplasmic reticulum (ER) stress depends on the activation of an integrated signal transduction pathway known as the unfolded protein response (UPR). Bax inhibitor-1 (BI-1) is an evolutionarily conserved ...