Browsing by Subject "p35"

Now showing items 1-3 of 3

    • Evidence for the participation of the neuron-specific CDK5 activator p35 during laminin-enhanced axonal growth 
      Paglini, Gabriela; Pigino, Gustavo; Kunda, Patricia; Morfini, Gerardo; Maccioni Baraona, Ricardo; Quiroga, Santiago; Ferreira, Adriana; Cáceres, Alfredo (1998)
      Cultures of cerebellar macroneurons were used to study the pattern of expression, subcellular localization, and function of the neuronal cdk5 activator p35 during laminin-enhanced axonal growth. The results obtained indicate ...
    • p35 and Rac1 underlie the neuroprotection and cognitive improvement induced by CDK5 silencing 
      Posada Duque, Rafael; López Tobon, Alejandro; Piedrahita, Diego; González Billault, Christian; Cardona Gómez, Gloria (Wiley & Sons, 2015)
      CDK5 plays an important role in neurotransmission and synaptic plasticity in the normal function of the adult brain, and dysregulation can lead to Tau hyperphosphorylation and cognitive impairment. In a previous study, we ...
    • TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells 
      Utreras Puratich, Elías; Prochazkova, Michaela; Terse, Anita; Gross, Jacklyn; Keller, Jason; Iadarola, Michael J.; Kulkarni, Ashok B. (2013)
      Background: Odontoblasts are specialized cells that form dentin and they are believed to be sensors for tooth pain. Transforming growth factor-β1 (TGF-β1), a pro-inflammatory cytokine expressed early in odontoblasts, plays ...