Browsing by Title Facultad de Medicina
Now showing items 10662-10681 of 12961
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Role of the RhoA/ROCK pathway in high-altitude associated neonatal pulmonary hypertension in lambs (Amer Physiological Soc, 2016)Exposure to high-altitude chronic hypoxia during pregnancy may cause pulmonary hypertension in neonates, as a result of vasoconstriction and vascular remodeling. We hypothesized that susceptibility to pulmonary hypertension, ...
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(Wiley, 2017)BackgroundIntrathecal/intracisternal BDNF in rodents produces long-lasting hyperalgesia/allodynia, which implies BDNF plays a role in the establishment and maintenance of central sensitization. Both self-regeneration of ...
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(BioScientifica Ltd., 2010)Fifty to seventy percent of patients with polycystic ovary syndrome (PCOS) present hyperinsulinemia. On the other hand, reports indicate that forkhead box class O 1 (FOXO1) and peroxisome proliferator-activated receptor-g ...
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(2013)The endoplasmic reticulum (ER) is a key subcellular compartment involved in the folding and maturation of around one-third of the total proteome. Accumulation of misfolded proteins in the ER lumen engages a signal transduction ...
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(2011)Using an integrative approach at the whole animal, isolated vessels, and molecular levels, we tested the hypothesis that the llama, a species that undergoes pregnancy under the influence of the chronic hypoxia of high ...
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(SOC BIOLGIA CHILE, 2006)Thyroid hormone (TH; 3,3,,5-triiodothyronine, T-3) is required for the normal function of most tissues, with major effects on O-2 consumption and metabolic rate. These are due to transcriptional activation of respiratory ...
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(Universidad de la Frontera, 2016)© 2016, Universidad de la Frontera. All rights reserved. Sonic hedgehog (SHH) is an essential morphogen for the development of neural tube, members and somites. Variations in expression can cause abnormalities in the nervous ...
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(HINDAWI PUBLISHING CORPORATION, 2006)Alzheimer's disease is the principal cause of dementia throughout the world and the fourth cause of death in developed economies. This brain disorder is characterized by the formation of brain protein aggregates, namely, ...
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(Elsevier, 2014)One of the properties of bacteria is their capacity to acquire large fragments of genomic DNA from other bacteria or to loose important parts of their own genome. Such fragments include genomic islands (GIs); nine GIs ...
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(2012)The genomic island 3 (GI-3) shared by Brucella melitensis and Brucella abortus contains 29 genes encoding mostly unknown proteins. Within this island, the open reading frames (ORFs) BAB1_0278 and BAB1_0263 are present, ...
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(2012)In Latin America, there are about 10-12 million people infected with Trypanosoma cruzi, the agent of Chagas' disease, one of the most important neglected tropical parasitism. Identification of molecular targets, specific ...
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(Cell Press, 2016)
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(Public Library Science, 2015)During exercise, skeletal muscle produces reactive oxygen species (ROS) via NADPH oxidase (NOX2) while inducing cellular adaptations associated with contractile activity. The signals involved in this mechanism are still a ...
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(Public Library of Science, 2015)© 2015 Díaz-Vegas et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
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(American Society for Nutrition, 2017)Background: Rosa mosqueta (RM) oil is characterized by high concentrations of antioxidants and alpha-linolenic acid (ALA; 18: 3n-3). We have previously demonstrated in male C57BL/6J mice that RM decreases hepatic steatosis, ...
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(Universidad de Chile, 2018)La resistencia a la insulina es un estado fisiopatológico altamente prevalente que antecede la aparición de diabetes tipo II. La obesidad como factor predisponente a estas patologías, se asocia a un estado de lipotoxicidad ...
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(2011)Rotarix® was first licensed in 2004 and rapidly introduced into private and public markets worldwide. In a previous 2009 article, we reviewed the impact of rotavirus-associated disease, the rationale for different vaccines, ...
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(2007)Rotavirus is the most common cause of severe gastroenteritis in children younger than 3 years of age worldwide. New rotavirus vaccine candidates were required to confer early protection against the most common rotavirus ...
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(1983)We studied the involvement of the cholinergic system in the contralateral head-eye-body turning induced in the cat through stimulation of the pulvinar-lateralis posterior nucleus complex (P-LP). In 17 cats through a cannula ...