Browsing by Title Facultad de Medicina

Now showing items 10682-10701 of 12946

    • RUNX2 promueve la progresión tumor en osteosarcoma 
      Vega Villa, Óscar Andrés (Universidad de Chile, 2011)
      El Osteosarcoma (OS) es el tumor sólido maligno más frecuente en la infancia y la adolescencia, corresponde al 20% de todos los tumores óseos y al 5% de los cánceres pediátricos. Los tratamientos actuales logran tasas ...
    • Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors 
      Teplyuk, Nadiya M.; Galindo, Mario A.; Teplyuk, Viktor I.; Pratap, Jitesh; Young, Daniel W.; Lapointe, David; Javed, Amjad; Stein, Janet L.; Lian, Jane B.; Stein, Gary S.; Van Wijnen, Andre J. (2008)
      Runt-related transcription factor 2 (Runx2) controls lineage commitment, proliferation, and anabolic functions of osteoblasts as the subnuclear effector of multiple signaling axes (e.g. transforming growth factor-β/BMP-SMAD, ...
    • Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation ... 
      Pereira, Barry P.; Zhou, Yefang; Gupta, Anurag; Leong, David T.; Aung, Khin Zarchi; Ling, Ling; Pho, Robert W.H.; Galindo, Mario A.; Salto-Tellez, Manuel; Stein, Gary S.; Cool, Simon M.; Van Wijnen, Andre J.; Nathan, Saminathan S. (2009)
      Osteosarcomas are the most prevalent primary bone tumors found in pediatric patients. To understand their molecular etiology, cell culture models are used to define disease mechanisms under controlled conditions. Many ...
    • Ruptured subscapular liver hematoma in context of HELLP syndrome Hematoma subcapsular hepático roto en ... 
      Henríquez-Villaseca, María Paz; Catalán-Barahona, Alejandra; Lattus-Olmos, José; Vargas-Valdebenito, Karina; Silva-Ruz, Solange (Sociedad Medica de Santiago, 2018)
      © 2018, Sociedad Medica de Santiago. All rights reserved. Background: Ruptured subscapular liver hematoma in context of HELLP syndrome is a rare complication with high mortality. Clinical presentation is nonspecific: ...
    • RvE1 Impacts the gingival inflammatory infiltrate by inhibiting the t cell response in experimental periodontitis 
      Álvarez, Carla; Abdalla, Henrique; Sulliman, Salwa; Rojas, Paola; Wu, Yu-Chiao; Almarhoumi, Rawan; Huang, Ren-Yeong; Galindo Díaz, Mario Alex; Vernal Astudillo, Rolando Marcelo; Kantarci, Alpdogan (Frontiers Media, 2021)
      Periodontitis is a chronic inflammatory disease associated with the formation of dysbiotic plaque biofilms and characterized by the progressive destruction of the alveolar bone. The transition from health to disease is ...
    • Ryanodine receptor-mediated Ca2+ release underlies iron-induced mitocondrial fission and stimulates ... 
      San Martín Rovirosa, Carol; Paula Lima, Andrea; García, Alejandra; Barattini, Pablo; Hartel, Steffen; Núñez González, Marco; Hidalgo Tapia, María Cecilia (2014)
      Mounting evidence indicates that iron accumulation impairs brain function. We have reported previously that addition of sub-lethal concentrations of iron to primary hippocampal neurons produces Ca2+ signals and promotes ...
    • RyR1-mediated Ca2+ Leak and Ca2+ Entry Determine Resting Intracellular Ca2+ in Skeletal Myotubes 
      Eltit Ortega, José Miguel; Yang, Tianzhong; Li, Hongli; Molinski, Tadeusz F.; Pessah, Isaac N.; Allen, Paul D.; López, José R. (American Society for Biochemistry and Molecular Biology, Inc., 2010-04-30)
      The control of resting free Ca2+ in skeletal muscle is thought to be a balance of channels, pumps, and exchangers in both the sarcolemma and sarcoplasmic reticulum. We explored these mechanisms using pharmacologic and ...
    • S-glutathionylation decreases Mg2+ inhibition and S-nitrosylation enhances Ca2+ activation of RyR1 channels 
      Aracena Parks, Paula; Sánchez, Gina; Donoso Laurent, Paulina; Hamilton, Susan L.; Hidalgo Tapia, María Cecilia (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2003-10-31)
      We have analyzed the effects of the endogenous redoxactive agents S-nitrosoglutathione and glutathione disulfide, and the NO donor NOR-3, on calcium release kinetics mediated by ryanodine receptor channels. Incubation of ...
    • SAC phosphoinositide phosphatases at the tonoplast mediate vacuolar function in Arabidopsis 
      Nováková, Petra; Hirsch, Sibylle; Feraru, Elena; Tejos, Ricardo; Van Wijk, Ringo; Viaene, Tom; Heilmann, Mareike; Lerche, Jennifer; De Rycke, Riet; Feraru, Mugurel I.; Grones, Peter; Van Montagu, Marc; Heilmann, Ingo; Munnik, Teun; Frimla, Jirí (2014)
      Phosphatidylinositol (PtdIns) is a structural phospholipid that can be phosphorylated into various lipid signaling molecules, designated polyphosphoinositides (PPIs). The reversible phosphorylation of PPIs on the 3, 4, or ...
    • Sacadas repetidas y estimulación táctil bilateral, formas de afectar procesos atencionales 
      Peñafiel Poblete, Claudio Antonio (Universidad de Chile, 2017)
      Se encuentra establecido que la cognición ejerce efectos en el movimiento, pero no se encuentra completamente si el movimiento tiene efectos sobre la cognición. El “Eye Movement Desensitation and Reproccesing“ (E.M.D.R.) ...
    • Saccade-related modulations of neuronal excitability support synchrony of visually elicited spikes 
      Ito, Junji; Maldonado Arbogast, Pedro; Singer, Wolf; Grün, Sonja (2011)
      During natural vision, primates perform frequent saccadic eye movements, allowing only a narrow time window for processing the visual information at each location. Individual neurons may contribute only with a few spikes ...
    • Saccadic modulation of cell discharges in the lateral geniculate nucleus 
      Montero, Vicente M.; Robles, Luis (1971)
      The effect of fast phases of vestibular nystagmus on evoked and spontaneous discharges of neurons in the lateral geniculate nucleus of the rat have been studied. In order to determine the central influence of saccadic ...
    • Saccharin consumption and the effect of a long-term exposure to a sweetened alcoholic solution in high- ... 
      Tampier de Jong, Lutske; Quintanilla González, María Elena (2006)
      An association between saccharin consumption and alcohol intake has been observed in rodent lines genetically developed for alcohol preference or alcohol avoidance. It has also been proposed that a sweetened alcohol solution ...
    • Saccharin consumption and the effect of a long-term exposure to a sweetened alcoholic solution in high- ... 
      Tampier de Jong, Lutske; Quintanilla González, María Elena (PERGAMON-ELSEVIER SCIENCE LTD, 2005-08)
      An association between saccharin consumption and alcohol intake has been observed in rodent lines genetically developed for alcohol preference or alcohol avoidance. It has also been proposed that a sweetened alcohol ...
    • Safeguarding vaccine production and supply strategies for polio eradication endgame 
      Bandyopadhyay, Ananda S.; O'Ryan Gallardo, Miguel (Elsevier, 2021)
    • Safety and effectiveness of progressive moderate-to-vigorous intensity elastic resistance training on ... 
      Calatayud, Joaquín; Pérez Alenda, Sofía; Carrasco, Juan J.; Cruz Montecinos, Carlos; Andersen, Lars L.; Bonanad, Santiago; Querol, Felipe; Megías Vericat, Juan E.; Casaña, José (Oxford Univ Press Inc, 2020)
      Objective. Strength training is recommended for people with hemophilia; however, published data are anecdotal and have methodological limitations. The purpose of this study was to evaluate the safety and effectiveness ...
    • Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis 
      Ruiz Palacios, Guillermo M.; Pérez Schael, Irene; Velázquez, F. Raúl; Abate, Héctor; Breuer, Thomas; Costa Clemens, SueAnn; Cheuvart, Brigitte; Espinoza, Félix; Gillard, Paul; Innis, Bruce L.; Cervantes, Yolanda; Linhares, Alexandre C.; López, Pío; Macías Parra, Mercedes; Ortega Barría, Eduardo; Richardson, Vesta; Rivera Medina, Doris Maribel; Rivera, Luis; Salinas, Belén; Pavia Ruz, Noris; Salmerón, Jorge; Rüttimann, Ricardo; Tinoco, Juan Carlos; Rubio, Pilar; Núñez, Ernesto; Guerrero, Lourdes; Yarzábal, Juan Pablo; Damaso, Silvia; Tornieporth, Nadia; Sáez Llorens, Xavier; Vergara, Rodrigo F.; Vesikari, Timo; Bouckenooghe, Alain; Clemens, Ralf; De Vos, Béatrice; O'Ryan Gallardo, Miguel (Massachusetts Medical Soc, 2006-01-05)
      BACKGROUND: The safety and efficacy of an attenuated G1P[8] human rotavirus (HRV) vaccine were tested in a randomized, double-blind, phase 3 trial. METHODS: We studied 63,225 healthy infants from 11 Latin American ...
    • Safety and efficacy of vildagliptin in real life chilean diabetic patients Evaluación del perfil de eficacia ... 
      Gonzalo Godoy, J.; Gutiérrez, Vicente; Montecinos, Mario; Yenes, Alejandro (Sociedad Medica de Santiago, 2015)
      © 2015, Sociedad Medica de Santiago. All rights reserved. Background: Vildagliptin is a dipeptidyl peptidase IV inhibitor (DPP4i). Its efficacy and safety of DPP4i in Chilean real life type 2 diabetic (T2D) patients is not ...
    • Safety and efficacy of vildagliptin in real life chilean diabetic patients Evaluación del perfil de eficacia ... 
      Gonzalo Godoy, J.; Gutiérrez, Vicente; Montecinos, Mario; Yenes, Alejandro (Sociedad Medica de Santiago, 2015)
      © 2015, Sociedad Medica de Santiago. All rights reserved. Background: Vildagliptin is a dipeptidyl peptidase IV inhibitor (DPP4i). Its efficacy and safety of DPP4i in Chilean real life type 2 diabetic (T2D) patients is not ...
    • Safety and hemodynamic response of regadenoson stress cardiovascular magnetic resonance imaging in heart ... 
      Sáenz Diez, J. Muniz; Luque González, M.; Martínez León, A.; Ibero Valencia, J.; Iglesias Colino, E.; Riesgo García, A.; Shangutov Kulichok, O.; Torre Carazo, F. de la; Rodríguez Junquera, M.; Irazusta Olloquiegui, X.; Soriano Aguadero, I.; Caballeros, M.; Salterain González, N.; Rábago G., Juan Aracil; Bastarrika, G. (Oxford Univ Press, 2020)