Rotavirus Serum IgA Immune Response in Children Receiving Rotarix Coadministered With bOPV or IPV
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2016Metadata
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Ramani, Sasirekha
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Rotavirus Serum IgA Immune Response in Children Receiving Rotarix Coadministered With bOPV or IPV
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Abstract
Background: Vaccine schedules including bivalent oral and inactivated
poliovirus vaccines will replace trivalent oral poliovirus vaccines in 2016.
Methods: We evaluated rotavirus immunoglobulin A seroresponses when
the second dose of Rotarix at 16 weeks was given concomitantly with inactivated
or bivalent oral poliovirus vaccines.
Results: Rotavirus immunoglobulin A seroresponse rate at week 28 was
15% lower in recipients of bivalent oral poliovirus vaccines compared with
inactivated poliovirus vaccines.
Conclusion: Bivalent oral poliovirus vaccine decreases rotavirus IgA
seroresponse rates when coadministered at 16 weeks of age.
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Pediatric Infectious Disease Journal. Volumen: 35 Número: 10 Páginas: 1137-1139
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