Browsing by Title Facultad de Medicina

Now showing items 3626-3645 of 12946

    • Dyspnoea and respiratory muscle ultrasound to predict extubation failure 
      Dres, Martin; Similowski, Thomas; Goligher, Ewan C.; Pham, Tai; Sergenyuk, Liliya; Telias, Irene; Grieco, Domenico Luca; Ouechani, Wissale; Junhasavasdikul, Detajin; Sklar, Michael C.; Damiani, L. Felipe; Melo, Luana; Santis, César; Degravi, Lauriane; Decavele, Maxens; Brochard, Laurent; Demoule, Alexandre (European Respiratory Soc, 2021)
      Background This study investigated dyspnoea intensity and respiratory muscle ultrasound early after extubation to predict extubation failure. Methods The study was conducted prospectively in two intensive care units in ...
    • Dysregulated immune responses in COVID-19 patients correlating with disease severity and invasive oxygen ... 
      García González, Paulina; Tempio Sepúlveda, Fabián Ignacio; Fuentes, Camila; Merino, Consuelo; Vargas, Leonardo; Simon, Valeska; Ramírez Pereira, Mirliana; Rojas, Verónica; Tobar Almonacid, Eduardo Andres; Landskron Ramos, Glauben Tamara; Araya, Juan Pablo; Navarrete, Mariela; Bastías Oñate, Carla Belén; Tordecilla Fernández, Rocío Pilar; Varas, Macarena A.; Maturana, Pablo; Marcoleta Caldera, Andrés Esteban; Allende Connelly, Miguel Luis; Naves Pichuante, Rodrigo Antonio; Hermoso, Marcela Alejandra; Salazar Onfray, Flavio Andrés; López Nitsche, Mercedes Natalia; Bono Merino, María Rosa; Osorio Olivares, Fabiola Beatriz (Frontiers Media, 2021)
      The prognosis of severe COVID-19 patients has motivated research communities to uncover mechanisms of SARS-CoV-2 pathogenesis also on a regional level. In this work, we aimed to understand the immunological dynamics of ...
    • Dysregulation of in vitro cytokine production by monocytes during sepsis 
      Munoz, Carlos; Carlet, Jean; Fitting, Catherine; Misset, Benoit; Blériot, Jean Pierre; Cavaillon, Jean Marc (The American Society for Clinical Investigation, 1991)
      The production by monocytes of interleukin-1α (IL-1α), interleukin-β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNFα) in intensive care unit (ICU) patients with sepsis syndrome (n = 23) or noninfectious ...
    • Dysregulation of mitotic machinery genes precedes genome instability during spontaneous pre-malignant ... 
      Urzúa, Ulises; Ampuero Llanos, Sandra; Roby, Katherine F.; Owens, Garrison A.; Munroe, David J. (BioMed Central Ltd., 2016)
      © 2016 The Author(s). Background: Based in epidemiological evidence, repetitive ovulation has been proposed to play a role in the origin of ovarian cancer by inducing an aberrant wound rupture-repair process of the ovarian ...
    • E Prostanoid-1 receptor regulates renal medullary aENaC in rats infused with angiotensin II 
      González, Alexis A.; Céspedes, Carlos; Villanueva, Sandra; Michea Acevedo, Luis; Vio, Carlos P. (Elsevier Inc., 2009)
      E Prostanoid (EP) receptors play an important role in urinary Na+ excretion. In the kidney, the epithelial sodium channel (ENaC) is the rate-limiting-step for Na+ reabsorption. We hypothesized that activation of EP1/EP3 ...
    • E-cadherin determines Caveolin-1 tumor suppression or metastasis enhancing function in melanoma cells 
      Lobos González, Lorena; Aguilar, Lorena; Díaz Jara, Jorge; Díaz, Natalia; Urra, Hery; Torres Gómez, Vicente; Silva, Verónica; Fitzpatrick, Christopher; Lladser, Álvaro; Hoek, Keith S.; Leyton Campos, Lisette; Quest, Andrew F. G. (2013)
      Theroleofcaveolin-1(CAV1)incancerishighlycontroversial.CAV1suppressesgenesthatfavortumordevelopment, yet also promotes focal adhesion turnover and migration of metastatic cells. How these contrasting observations relate ...
    • The E180splice Mutation in the GHR Gene Causing Laron Syndrome: Witness of a Sephardic Jewish Exodus from ... 
      Goncalves, Fernanda T.; Fridman, Cintia; Pinto, Emília M.; Guevara Aguirre, Jaime; Shevah, Orit; Rosembloom, Arlan L.; Hwa, Vivian; Cassorla Goluboff, Fernando; Rosenfeld, Ron G.; Lins, Theresa; Damiani, Durval; Arnhold, Ivo; Laron, Zvi; Jorge, Alexander (Wiley, 2014)
      Laron syndrome(LS) is a genetic disorder caused by mutations in the growth hormone receptor (GHR) gene. The most frequent GHR mutation is E180splice (rs121909360), which was initially found in an inbred population of ...
    • E180splice mutation in the growth hormone receptor gene in a Chilean family with growth hormone insensitivity: ... 
      Espinosa, Claudia; Sjoberg, Marcela; Salazar, Teresa; Rodriguez, Adrian; Cassorla Goluboff, Fernando; Mericq, Verónica; Carvallo, Pilar (Freund Publishing House Ltd, 2008)
      Mutations in the GH receptor gene have been identified as the cause of growth hormone insensitivity syndrome (GHIS), a rare autosomal recessive disorder. We studied the clinical and biochemical characteristics and the ...
    • Earlier immunomodulatory treatment is associated with better visual outcomes in a subset of patients with ... 
      Urzúa Salinas, Cristhian; Velásquez Rojas, Víctor; Sabat Opazo, Pedro; Berger, Osvaldo; Ramírez, Sebastián; Goecke Sariego, Irmgadt; Vásquez, Darío H.; Gatica, Héctor; Guerrero, Julia (Wiley-Blackwell, 2015)
      Purpose: To evaluate clinical outcomes of first-line immunomodulatory therapy (IMT) and prednisone alone or late IMT in Vogt-Koyanagi-Harada disease. Methods: Retrospective cohort study of 152 patients with ...
    • Early acquisition of pneumocystis jirovecii colonization and potential association with respiratory distress ... 
      Rojas, Pilar; Friaza, Vicente; García, Elisa; Horra, Carmen de la; Vargas Munita, Sergio; Calderon, Enrique J.; Pavon, Antonio (Oxford University Press, 2017)
      Background. Pneumocystis pneumonia is a well-recognized lung disease of premature and malnourished babies. Even though serologic studies have shown that children are exposed to Pneumocystis jirovecii early in life, the ...
    • Early and late results of the acid suppression and duodenal diversion operation in patients with Barrett's ... 
      Csendes Juhasz, Attila; Burdiles, Patricio; Braghetto Miranda, Italo; Korn Bruzzone, Owen; Díaz, Juan Carlos; Rojas, Jorge (2002)
      The usual surgical treatment for patients with Barrett's esophagus (BE) is a classic Nissen fundoplication or posterior gastropexy with cardial calibration. However, some surgical reports as well as our experience suggest ...
    • Early behavioral risks of childhood and adolescent daytime urinary incontinence and nocturnal enuresis 
      Vasconcelos, Monica M.A.; East, Patricia; Blanco, Estela; Lukacz, Emily S.; Caballero, Gabriela; Lozoff, Betsy; Gahagan, Sheila (Lippincott Williams and Wilkins, 2017)
      Copyright 2017 Wolters Kluwer Health, Inc. All rights reserved.Objective: To investigate whether infant temperament and childhood internalizing, externalizing, and inattention symptoms increase the likelihood of daytime ...
    • Early Blood Pressure Lowering Does Not Reduce Growth of Intraventricular Hemorrhage following Acute ... 
      Chan, Edward; Anderson, Craig S.; Wang, Xia; Arima, Hisatomi; Saxena, Anubhav; Moullaali, Tom J.; Delcourt, Candice; Wu, Guojun; Wang, Jinchao; Chen, Guofang; Lavados Germain, Pablo Manuel; Stapf, Christian; Robinson, Thompson; Chalmers, John (S. Karger AG, 2016)
      © 2016 The Author(s). Background: Intraventricular hemorrhage (IVH) extension is common following acute intracerebral hemorrhage (ICH) and is associated with poor prognosis. Aim: To determine whether intensive blood pressure ...
    • Early detection in saliva of polypeptides associated to isoproterenol-induced mouse parotid hypertrophy 
      López Solís, Remigio; Puente Díaz, Margarita; Morales Bozo, Irene; Kemmerling Weis, Ulrike; Rojas Díaz, Francisco Rafael (2003)
      Chronic administration of isoproterenol (IPR) results in a marked hypertrophy and in the induction of a group of putative proline-rich polypeptides in the mouse parotid glands. Some of these polypeptides (pps C-G) have ...
    • Early diagnosis of phenylketonuria. Follow up of 2 cases Diagnostico precoz de fenilquetonuria. Seguimiento ... 
      Raimann,; Cornejo Cornejo, Jacqueline Alejandra; Perales,; Barros,; Moraga,; Colombo, (1992)
      A screening program for the early diagnosis of phenylketonuria was initiated 24 months ago in the Servicio de Salud Metropolitano Central. Since then, 2 cases with phenylketonuria have been early diagnosed. These patients ...
    • Early discoid lupus erythematosus protects against renal disease in patients with systemic lupus erythematosus: ... 
      Pons Estel, Guillermo; Aspey, L. D.; Bao, G.; Pons-Estel, Bernardo A.; Wojdyla, D.; Saurit, V.; Alvarellos, A.; Caeiro, F.; Haye Salinas, M. J.; Sato, E. I.; Soriano, E. R.; Costallat, L. T.L.; Neira, O.; Iglesias Gamarra, Antonio J.; Gil Reyes, Llerena; Cardiel, M. H.; Acevedo Vásquez, Eduardo (SAGE Publications Ltd, 2017)
      © SAGE Publications. Objectives The objective of this study was to examine whether early discoid lupus erythematosus (DLE) would be a protective factor for further lupus nephritis in patients with systemic lupus erythematosus ...
    • Early evaluation of Alzheimer's disease: Biomarkers and neuropsychological tests Evaluación de la enfermedad ... 
      Renzo Lanfranco, G.; Manríquez-Navarro, Paula; Leyla Avello, G.; Canales-Johnson, Andrés (2012)
      Alzheimer disease is a neurodegenerative condition that affects cognitive, behavioral and global functioning of patients. Currently and due to the lack of conclusive biological testing, Alzheimer's disease diagnosis is ...
    • Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced ... 
      Copaja Soto, Miguel; Valenzuela, Rodrigo; Saldaña, Adiela; Ocaranza, María Paz; Jalil Milad, Jorge; Vio, Carlos; Lijnen, Paul; Ordenes, Gamaliel; Vivar Sánchez, Raúl; Lavandero González, Sergio; Díaz Araya, Guillermo (SAGE PUBLICATIONS LTD, 2008-09)
      Introduction. Isoproterenol treatment of Brown Norway Lewis rats (high and low plasma angiotersin-I-converting enzyme activity., respectively) results in similar cardiac hypertrophy but higher cardiac fibrosis in Brown ...
    • Early gallbladder cancer: Is further treatment necessary? 
      Aretxabala, Xabier de; Roa, Iván; Hepp, Juan; Maluenda, Fernando; Mordojovich, Gerardo; Leon, Jorge; Roa, Juan (2009)
      Background and Objectives: The goal of this study was to evaluate a series of patients with early gallbladder cancer, focusing on the selection of treatment and the role of Rokitansky Aschoff sinus infiltration. Methods: ...
    • Early histological and functional effects of chronic copper exposure in rat liver 
      Cisternas, Felipe A.; Tapia Opazo, Gladys; Arredondo, Miguel; Cartier Ugarte, Denise; Romanque, Pamela; Sierralta, Walter D.; Vial, María T.; Videla Cabrera, Luis; Araya, Magdalena (2005)
      Cu is an essential trace element capable of producing toxic effects in animals and man when ingested acutely or chronically in excess. Although chronic Cu exposure is increasingly recognized as a public health issue, its ...