Browsing by Title Facultad de Medicina

Now showing items 8178-8197 of 12942

    • Myocardial infarction with non-obstructive coronary artery disease. Diagnostic value of intravascular imaging ... 
      Cataldo, VP; Verdugo, FJ; Dauvergne, C; Garcia, A; Antileo, P; Monsalve, R; Pineda, F; Mendez, M; Uriarte, P; Araya, HM; Llerena, P; Nauhm, Y; Pereira, G; Ramos, C; Coello, VM; Garrido, GC; Delgado, AT; Gonzalez, S; Sandoval, BJ (Sociedad Medica de Santiago, 2020)
    • Myocardial ischemia in patients older than 70 years of age. Clinical and angiographic aspects Cardiopatía ... 
      Ramírez Ramírez, Andrea; Araya Araya, Fernando; Aramburu,; Ayala,; Chamorro, G.; Silva Silva, Laura (1991)
      We studied 77 patients with clinical suspicion of ischemic heart disease whose age ranged from 70 to 84 years. Patients with atypical angina had mostly normal coronary arteries, while those with unstable angina usually had ...
    • Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure ... 
      Winter, José Luis; Castro, Pablo; Meneses, Luis; Chalhub, Mónica; Verdejo, Hugo; Greig, Douglas; Gabrielli, Luigi; Chiong Lay, Mario; Concepción, Roberto; Mellado, Rosemarie; Hernández, Claudia; Uribe, Sergio; Lavandero González, Sergio (2010)
      Background: Heart failure (HF) is characterized, among other features, by the development of alterations in myocardial energy metabolism, involving a decrease in glucose utilization and increased free fatty acid uptake by ...
    • Myotonic dystrophy in a female with myasthenia gravis 
      Avaria, María de los Angeles; Kleinsteuber Saa, Karin; Novoa, Fernando; Faúndez, Paola; Carvallo, Pilar (2007)
      The likelihood of coexistence in the same patient of myasthenia gravis and myotonic dystrophy has been estimated at I in 40 million. The case of a patient in whom both diagnoses were made is reported here. A 13-year-old ...
    • Myotube depolarization generates reactive oxygen species through NAD(P)H oxidase; ROS-elicited Ca2+ stimulates ... 
      Espinosa, Alejandra; Leiva, Aída; Peña, Marisol; Müller, Mariolly; Debandi Cuadra, Aníbal; Hidalgo Tapia, María Cecilia; Carrasco Friz, María Angélica; Jaimovich Pérez, Enrique (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2006-11)
      Controlled generation of reactive oxygen species (ROS) may contribute to physiological intracellular signaling events. We determined ROS generation in primary cultures of rat skeletal muscle after field stimulation (4001-ms ...
    • Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport 
      Mardones, Pablo; Rubinsztein, David; Hetz Flores, Claudio (AAAS, 2016)
      Although vertebrates cannot synthesize the natural disaccharide trehalose, exogenous administration of trehalose to mammalian cells may be beneficial for protein misfolding disorders. In this issue, DeBosch et al. show ...
    • n-3 LCPUFA in the reversal of hepatic steatosis: the role of ACOX and CAT-1 
      Tapia, G. S.; González Manan, D.; D'Espessailles Tapia, Amanda; Dossi, C. G. (2016)
      The aim of this study was to investigate the roles of the Acyl co-enzyme A oxidase (ACOX), carnitine acyl transferase I (CAT-1) and activating protein 1 (AP-1) in the reversal of hepatic steatosis with dietary change and ...
    • N-3 Long-Chain Polyunsaturated Fatty Acid Supplementation Significantly Reduces Liver Oxidative Stress in ... 
      Valenzuela, Rodrigo; Espinosa, Alejandra; González Mañán, Daniel Alonso; D'Espessailles Tapia, Amanda; Fernández Arancibia, Virginia; Videla Cabrera, Luis; Tapia Opazo, Gladys (2012)
      Omega-3 (n-3) long-chain polyunsaturated fatty acids (n-3 LCPUFA) are associated with several physiological functions, suggesting that their administration may prevent non transmissible chronic diseases. Therefore, we ...
    • N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation ... 
      Tapia Opazo, Gladys; Valenzuela Báez, Rodrigo; Espinosa Escalona, Berta; Romanque Ulloa, Pamela; Dossi Muñoz, Camila; González Mañán, Daniel Alonso; Videla Cabrera, Luis; D'Espessailles Tapia, Amanda (WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2014)
      Scope: Dietary n-3 long-chain PUFAs (n-3 LCPUFAs) supplementation was studied in an HFD-induced (HFD is high-fat diet) steatosis and inflammation in relation to peroxisome proliferator-activated receptor alpha (PPAR- ) ...
    • N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation ... 
      Tapia Opazo, Gladys; Valenzuela, Rodrigo; Espinosa, Alejandra; Romanque, Pamela; Dossi, Camila; González Mañán, Daniel Alonso; Videla Cabrera, Luis; D'Espessailles Tapia, Amanda (Wiley-VCH Verlag, 2014)
      Scope: Dietary n-3 long-chain PUFAs (n-3 LCPUFAs) supplementation was studied in an HFD-induced (HFD is high-fat diet) steatosis and inflammation in relation to peroxisome proliferator-activated receptor alpha (PPAR-α) and ...
    • N-3 Polyunsaturated Fatty Acids and Their Lipid Mediators as A Potential Immune-Nutritional Intervention: ... 
      Herrera Vielma, Francisca; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis Alberto; Zúñiga Hernández, Jéssica (MDPI, 2021)
      In recent years, the beneficial effect of n-3 polyunsaturated fatty acids (n-3 PUFAs) intake on human health has been widely accepted in the field of immunonutrition. Today, we find a diversity of supplements based on n-3 ...
    • N-3 PUFA supplementation triggers PPAR-α activation and PPAR-α/NF-κB interaction: Anti-inflammatory ... 
      Zúñiga, Jessica; Cancino, Milena; Medina, Fernando; Varela, Patricia; Vargas, Romina; Tapia Opazo, Gladys; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2011)
      Dietary supplementation with the n-3 polyunsaturated fatty acids (n-3 PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to rats preconditions the liver against ischemia-reperfusion (IR) injury, with reduction ...
    • N-6 -methyladenosine negatively regulates human respiratory syncytial virus replication 
      Figueroa, Fabián; Vega Gibson, Alonso Gonzalo; Catrileo, Joseline; Gaete Argel, Aracelly Janis; Riquelme Barrios, Sebastián Andrés; Alonso Palomares, Luis Antonio; Tapia Faúndes, Lorena; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo Andrés; Acevedo Acevedo, Mónica Loreto (Frontiers Media, 2021)
      N 6 -methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV). Here, we evaluated the impact of m6A writers, ...
    • N-Acetylcysteine and Acetylsalicylic Acid Inhibit Alcohol Consumption by Different Mechanisms: Combined Protection 
      Quintanilla González, María Elena; Ezquer, Fernando; Morales Retamales, Paola; Ezquer, Marcelo; Olivares, Belén; Santapau, Daniela; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Frontiers Media, 2020)
      Chronic ethanol intake results in brain oxidative stress and neuroinflammation, which have been postulated to perpetuate alcohol intake and to induce alcohol relapse. The present study assessed the mechanisms involved in ...
    • N-Acetylcysteine Reduces Skeletal Muscles Oxidative Stress and Improves Grip Strength in Dysferlin-Deficient ... 
      García Campos, Paz; Báez Matus, Ximena; Jara Gutiérrez, Carlos; Paz Araos, Marilyn; Astorga, César; Cea, Luis A.; Rodríguez, Viviana; Bevilacqua, Jorge A.; Caviedes, Pablo; Cárdenas, Ana M. (MDPI, 2020)
      Dysferlinopathy is an autosomal recessive muscular dystrophy resulting from mutations in the dysferlin gene. Absence of dysferlin in the sarcolemma and progressive muscle wasting are hallmarks of this disease. Signs of ...
    • N-Acetylcysteine, a glutathione precursor, reverts vascular dysfunction and endothelial epigenetic programming ... 
      Herrera, Emilio A.; Cifuentes Zúñiga, Francisca; Figueroa, Esteban; Villanueva, Cristian; Hernández, Cherie; Alegría, René; Arroyo Jousse, Viviana; Peñaloza, Estefania; Farías, Marcelo; Uauy Dagach-Imbarack, Ricardo; Casanello, Paola; Krause, Bernardo J. (Blackwell Publishing Ltd, 2017)
      © 2016 The Authors. The Journal of Physiology © 2016 The Physiological SocietyKey points: Intrauterine growth restriction (IUGR) is associated with vascular dysfunction, oxidative stress and signs of endothelial epigenetic ...
    • N-Methyl-d-Aspartate receptor modulation by Nicotinamide Adenine Dinucleotide Phosphate Oxidase type 2 ... 
      Plaza Briceño, Wladimir; Estay, Sebastián; Fuente Ortega, Erwin de la; Gutiérrez, Camilo; Sánchez Vergara, Gina; Hidalgo Tapia, María Cecilia; Chávez, Andrés; Haeger, Paola (Mary Ann Liebert, 2020)
      Aims: Pre- and/or early postnatal ethanol exposure (prenatal alcohol exposure [PAE]) impairs synaptic plasticity as well as memory formation, but the mechanisms underlying these effects remain unclear. Both long-term ...
    • N-methylaspartate-activated calcium channels in rat brain cortex slices. Effect of calcium channel blockers ... 
      Riveros, Felipe; Orrego, (1986)
      N-Methyl-dl-aspartate, l-glutamate, kainate and dl-homocysteate were found to increase the initial rate and the maximal uptake of 45Ca into the non-inulin space of rat brain cortex slices incubated in vitro. The ...
    • Na+, K+-ATPase and Ca2+-ATPase activities in basal and microvillous syncytiotrophoblast membranes from ... 
      Abad, Cilia; Vallejos, Catalina; De Gregorio, Nicole; Paredes Díaz, Paula Andrea; Chiarello, Delia I.; Contreras Mendoza, Mariana; Piñero, Sandy; Proverbio, Teresa; Botana, Desirée; Rojas, Próspero; Riquelme, Gloria; Proverbio, Fulgencio; Marín, Reinaldo (Informa Healthcare, 2015)
      Objective: The aim of this study is to evaluate the effect of preeclampsia on the level of lipid peroxidation, activity and expression of both plasma membrane Ca2+- and Na+, K+-ATPases in syncytiotrophoblast. Methods: The ...
    • Nacimiento anómalo de las arterias coronarias en 10.000 pacientes adultos sometidos a coronariografía 
      Ugalde Prieto, Héctor; Ramírez, Alfredo; Ugalde, Diego; Farías, Eric; Silva, Ana María (2010)
      Background: Between 0.3 and 1.3% of coronary arteries have anomalous origins. Circumflex artery has the higher frequency of anomalies. Aim: To study the frequency of congenital anomalous origins of coronary arteries among ...