Browsing by Author "Abarzúa Catalán, Lorena"

Now showing items 1-8 of 8

    • A Circadian Clock Entrained by Melatonin Is Ticking in the Rat Fetal Adrenal 
      Torres Farfán, Claudia; Méndez, N.; Abarzúa Catalán, Lorena; Vilches, N.; Valenzuela, G. J.; Serón Ferré, María (ENDOCRINE SOC, 2011-05)
      The adrenal gland in the adult is a peripheral circadian clock involved in the coordination of energy intake and expenditure, required for adaptation to the external environment. During fetal life, a peripheral circadian ...
    • Circadian rhythms in the fetus 
      Serón Ferré, María; Méndez, Natalia; Abarzúa Catalán, Lorena; Vilches, Nelson; Valenzuela, Francisco J.; Reynolds, Henry E.; Llanos Mansilla, Jorge; Rojas, Auristela; Valenzuela, Guillermo J.; Torres Farfán, Claudia (Elsevier, 2012)
      Throughout gestation, the close relationship between mothers and their progeny ensures adequate development and a successful transition to postnatal life. By living inside the maternal compartment, the fetus is inevitably ...
    • Cryptochrome 2 expression level is critical for adrenocorticotropin stimulation of cortisol production in ... 
      Torres Farfán, Claudia; Abarzúa Catalán, Lorena; Valenzuela, F. J.; Mendez, N.; Richter, H. G.; Valenzuela, G. J.; Serón Ferré, María (2009)
      Timely production of glucocorticoid hormones in response to ACTH is essential for survival by coordinating energy intake and expenditure and acting as homeostatic regulators against stress. Adrenal cortisol response to ...
    • Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: ... 
      Kato, Sumie; Abarzúa Catalán, Lorena; Trigo, César; Delpiano, Ana; Sanhueza, Cristóbal; García, Karen; Ibáñez, Carolina; Hormazábal, Katherine; Díaz, Daniela; Brañes, Jorge; Castellón Vera, Enrique; Bravo, Erasmo; Owen, Gareth; Cuello, Mauricio (Impact Journals LLC, 2015)
      The evidence linking obesity with ovarian cancer remains controversial. Leptin is expressed at higher levels in obese women and stimulates cell migration in other epithelial cancers. Here, we explored the clinical impact ...
    • Melatonin exerts direct inhibitory actions on ACTH responses in the human adrenal gland 
      Campino, C.; Valenzuela, F. J.; Torres Farfán, Claudia; Reynolds, H. E.; Abarzúa Catalán, Lorena; Arteaga, E.; Trucco, C.; Guzmán, S.; Valenzuela, G. J.; Serón Ferré, María (2011)
      In nonhuman primates and rodents, melatonin acting directly on the adrenal gland, inhibits glucocorticoid response to ACTH. In these species, an intrinsic adrenal circadian clock is involved in ACTH-stimulated glucocorticoid ...
    • Neuronal rubicon represses extracellular APP/amyloid beta deposition in Alzheimer's disease 
      Espinoza, Sandra; Grunenwald, Felipe; Gomez, Wileidy; García, Felipe; Abarzúa Catalán, Lorena; Oyarce Pezoa, Sebastián; Hernández, María Fernanda; Cortés, Bastián I.; Uhrig, Markus; Ponce de la Vega, Daniela Paz; Durán Aniotz, Claudia; Hetz Flores, Claudio Andres; San Martín Rovirosa, Carol Dazil; Cornejo Corona, Víctor Hugo; Ezquer, Fernando; Parra Ortiz, Valentina María; Behrens Pellegrino, María Isabel Ofelia; Manque, Patricio A.; Rojas Rivera, Diego; Vidal, René L.; Woehlbier, Ute; Nassif, Melissa (MDPI, 2022)
      Alzheimer's disease (AD) is the most prevalent age-associated neurodegenerative disease. A decrease in autophagy during aging contributes to brain disorders by accumulating potentially toxic substrates in neurons. Rubicon ...
    • Rhythmic expression of functional MT1 melatonin receptors in the rat adrenal gland 
      Richter, Hans G.; Torres Farfán, Claudia; García Sesnich, Jocelyn; Abarzúa Catalán, Lorena; Henríquez Luna, Mauricio; Alvarez Felmer, Mauro; Gaete, Fernando; Rehren, Germán E.; Serón Ferré, María (ENDOCRINE SOC, 2008-03)
      We previously demonstrated that melatonin is involved in the regulation of adrenal glucocorticoid production in diurnal primates through activation of MT1 membrane-bound melatonin receptors. However, whether melatonin ...
    • Timed maternal melatonin treatment reverses circadian disruption of the fetal adrenal clock imposed by ... 
      Méndez, Natalia; Abarzúa Catalán, Lorena; Vilches, Nelson; Galdames, Hugo A.; Spichiger, Carlos; Richter, Hans G.; Valenzuela, Guillermo J.; Serón Ferré, María; Torres Farfán, Claudia (2012)
      Surprisingly, in our modern 24/7 society, there is scant information on the impact of developmental chronodisruption like the one experienced by shift worker pregnant women on fetal and postnatal physiology. There are ...