Browsing by Author "Lavandero González, Sergio"

Now showing items 1-3 of 3

    • Methods for studying primary cilia in heart tissue after ischemia-reperfusion injury 
      Kretschmar, Catalina; Hernández Cáceres, María Paz; Reyes Rojas, Montserrat; Peña Oyarzún, Daniel; García Navarrete, Camila; Troncoso Cotal, Rodrigo Hernán; Díaz Castro, Francisco; Budini Budini, Mauricio Fernando; Morselli, Eugenia; Riquelme Meléndez, Jaime Andrés; Hill, Joseph A.; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Elsevier, 2023)
      Cardiovascular diseases are the leading cause of death and disability worldwide. After heart injury triggered by myocardial ischemia or myocardial infarction, extensive zones of tissue are damaged and some of the tissue ...
    • New emerging roles of Polycystin-2 in the regulation of autophagy 
      Peña Oyarzún, Daniel; Batista González, Ana; Kretschmar, Catalina; Burgos, Paulina; Lavandero González, Sergio; Morselli, Eugenia; Criollo Céspedes, Alfredo (Elsevier, 2020)
      Polycystin-2 (PC2) is a calcium channel that can be found in the endoplasmic reticulum, the plasmatic membrane, and the primary cilium. The structure of PC2 is characterized by a highly ordered C-terminal tail with an ...
    • PKD2/polycystin-2 induces autophagy by forming a complex with BECN1 
      Peña Oyarzún, Daniel; Rodríguez Peña, Marcelo; Burgos Bravo, Francesca; Vergara, Ángelo; Kretschmar Montecinos, Catalina; Sotomayor Flores, Cristián; Ramírez Sarmiento, César A.; De Smedt, Humbert; Reyes Rojas, Montserrat; Pérez, William; Torres Gómez, Vicente; Morselli, Eugenia; Altamirano, Francisco; Wilson, Christian; Hill, Joseph A.; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Taylor & Francis, 2020)
      Macroautophagy/autophagy is an intracellular process involved in the breakdown of macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 (polycystin 2, transient receptor potential cation channel), a ...