Browsing by Author "Smith, P. C."

Now showing items 1-5 of 5

    • Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E-2 production in human ... 
      Romero, A.; Cáceres, M.; Arancibia, R.; Silva, D.; Couve, E.; Martínez, C.; Martínez, J.; Smith, P. C. (Wiley-Blackwell, 2015)
      Background: Granulation tissue remodeling and myofibroblastic differentiation are critically important events during wound healing. Tobacco smoking has a detrimental effect in gingival tissue repair. However, studies ...
    • Differential uPA expression by TGF-beta 1 in gingival fibroblasts 
      Smith, P. C.; Martínez, J. (INT AMER ASSOC DENTAL RESEARCHI A D R/A A D R, 2006-02)
      Transforming Growth Factor-beta 1 (TGF-beta 1) plays a key role in connective tissue remodeling and inflammation. Under pathological conditions, like periodontal disease, fibroblasts may display an altered response to this ...
    • Gingival Wound Healing: An Essential Response Disturbed by Aging? 
      Smith, P. C.; Cáceres Lluch, Mónica; Martínez, C.; Oyarzún, A.; Martínez, J. (International & American Associations for Dental Research, 2015)
      Gingival wound healing comprises a series of sequential responses that allow the closure of breaches in the masticatory mucosa. This process is of critical importance to prevent the invasion of microbes or other agents ...
    • Involvement of MT1-MMP and TIMP-2 in human periodontal disease 
      Oyarzún, A.; Arancibia, R.; Hidalgo Acosta, Rodrigo; Peñafiel, C.; Cáceres, M.; González, M. J.; Martínez, J.; Smith, P. C. (John Wiley, 2010)
      OBJECTIVES: Periodontal disease is characterized by an increased collagen metabolism. Although membrane type-1 matrix metalloproteinase (MT1-MMP) plays a critical role in collagen degradation, its involvement in human ...
    • Tumor necrosis factor-astimulated membrane type 1-matrix metalloproteinase production is modulated by ... 
      Smith, P. C.; Guerrero, J.; Tobar, N.; Cáceres, M.; González Burgos, María Julieta; Martínez Winkler, Jorge (Blackwell Munksgaard, 2007-12-11)
      Membrane type 1-matrix metalloproteinase (MT1- MMP) is a collagenolytic enzyme involved in connective tissue remodeling. In periodontal tissues, either cytokines or growth factors regulate the production of proteolytic ...