Browsing by Subject "Macrophage"

Now showing items 1-3 of 3

    • The effects of immunomodulation by macrophage subsets on osteogenesis in vitro 
      Loi, Florence; Córdova Jara, Luis; Zhang, Ruth; Pajarinen, Jukka; Lin, Tzu-hua; Goodman, Stuart B.; Yao, Zhenyu (BioMed Central, 2016)
      Background: Bone formation and remodeling are influenced by the inflammatory state of the local microenvironment. In this regard, macrophages are postulated to play a crucial role in modulating osteogenesis. However, the ...
    • Innate Phagocyte Polarization in the Oral Cavity 
      Metcalfe, Sarah; Anselmi, Natalie; Escobar Álvarez, Alejandro Felipe; Visser, Michelle B.; Kay, Jason G. (Frontiers Media, 2022)
      The oral cavity is a complex environment constantly exposed to antigens from food and the oral microbiota. Innate immune cells play an essential role in maintaining health and homeostasis in the oral environment. However, ...
    • Mutant CCL2 protein coating mitigates wear particle-induced bone loss in a murine continuous polyethylene ... 
      Nabeshima, Akira; Pajarinen, Jukka; hua Lin, Tzu; Jiang, Xinyi; Gibon, Emmanuel; Córdova, Luis; Loi, Florence; Lu, Laura; Jämsen, Eemeli; Egashira, Kensuke; Yang, Fan; Yao, Zhenyu; Goodman, Stuart (Elsevier Ltd, 2017)
      Wear particle-induced osteolysis limits the long-term survivorship of total joint replacement (TJR). Monocyte/macrophages are the key cells of this adverse reaction. Monocyte Chemoattractant Protein-1 (MCP-1/CCL2) is the ...